Emcure Pharmaceuticals Limited (Emcure) is an Indian multinational

pharmaceutical Medication (also called medicament, medicine, pharmaceutical drug, medicinal product, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease. Drug therapy ( pharmacotherapy) is an important part of the ...

company, headquartered in

Pune Pune ( ; , ISO 15919, ISO: ), previously spelled in English as Poona (List of renamed Indian cities and states#Maharashtra, the official name until 1978), is a city in the state of Maharashtra in the Deccan Plateau, Deccan plateau in Western ...

. Emcure's product portfolio includes tablets, capsules (both softgel capsules and hard-gel capsules) and injectables. The company produces

gynaecology Gynaecology or gynecology (see American and British English spelling differences) is the area of medicine concerned with conditions affecting the female reproductive system. It is often paired with the field of obstetrics, which focuses on pre ...

cardiovascular In vertebrates, the circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the body. It includes the cardiovascular system, or vascular system, that consists of the heart a ...

oncology Oncology is a branch of medicine that deals with the study, treatment, diagnosis, and prevention of cancer. A medical professional who practices oncology is an ''oncologist''. The name's Etymology, etymological origin is the Greek word ὄγ ...

and

blood Blood is a body fluid in the circulatory system of humans and other vertebrates that delivers necessary substances such as nutrients and oxygen to the cells, and transports metabolic waste products away from those same cells. Blood is com ...

therapeutic drugs Pharmacology is the science of drugs and medications, including a substance's origin, composition, pharmacokinetics, pharmacodynamics, therapeutic use, and toxicology. More specifically, it is the study of the interactions that occur between ...

HIV The human immunodeficiency viruses (HIV) are two species of '' Lentivirus'' (a subgroup of retrovirus) that infect humans. Over time, they cause acquired immunodeficiency syndrome (AIDS), a condition in which progressive failure of the im ...

antivirals Antiviral drugs are a class of medication used for treating viral infections. Most antivirals target specific viruses, while a broad-spectrum antiviral is effective against a wide range of viruses. Antiviral drugs are a class of antimicrobials ...

and other anti-infectives, and vitamins and minerals.

History

Emcure Pharmaceuticals was established in 1981 by Satish Mehta, who began the company with a bank loan of 3

lakh A lakh (; abbreviated L; sometimes written lac) is a unit in the Indian numbering system equal to one hundred thousand (100,000; scientific notation: 105). In the Indian 2, 2, 3 convention of digit grouping, it is written as 1,00,000. F ...

(about US$35,000 then) after graduating from IIM-A. In the 1990s, the company transitioned from being a

contract manufacturing organization A contract manufacturing organization (CMO), more recently referred to (and more commonly used now) as a contract development and manufacturing organization (CDMO) to avoid the acronym confusion of Chief Medical Officer or Clinical Monitoring Organ ...

to a producer of

generic drug A generic drug is a pharmaceutical drug that contains the same chemical substance as a drug that was originally protected by chemical patents. Generic drugs are allowed for sale after the patents on the original drugs expire. Because the active ch ...

s. In 2006, Emcure signed license agreements with

Bristol-Myers Squibb The Bristol-Myers Squibb Company, doing business as Bristol Myers Squibb (BMS), is an American multinational pharmaceutical company. Headquartered in Princeton, New Jersey, BMS is one of the world's largest pharmaceutical companies and consist ...

for Atazanavir and

Gilead Sciences Gilead Sciences, Inc. () is an American biopharmaceutical company headquartered in Foster City, California, that focuses on researching and developing antiviral drugs used in the treatment of HIV/AIDS, hepatitis B, hepatitis C, influenza, and CO ...

for

Tenofovir Tenofovir disoproxil, sold under the brand name Viread among others, is a medication used to treat chronic hepatitis B and to prevent and treat HIV/AIDS. It is generally recommended for use with other antiretrovirals. It may be used for pr ...

as part of their Global Access Programs. In 2012,

Roche F. Hoffmann-La Roche AG, commonly known as Roche (), is a Switzerland, Swiss multinational corporation, multinational holding healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics. Its holding company, ...

signed a deal with Emcure for manufacturing its blockbuster anticancer drugs

Herceptin Trastuzumab, sold under the brand name Herceptin among others, is a monoclonal antibody used to treat breast cancer and stomach cancer. It is specifically used for cancer that is HER2 receptor positive. It may be used by itself or together w ...

and Mabthera in India. Under this programme the cancer drugs shall be made available to the developing world at an affordable 'cut-price' version. In 2013, Emcure established a health foods venture in partnership with cricketer

MS Dhoni Mahendra Singh Dhoni (; born 7 July 1981) is an Indian professional cricketer who plays as a right-handed batter and a wicket-keeper. Widely regarded as one of the most prolific wicket-keeper batsmen and captains and one of the greatest O ...

, and Dhoni was signed up as Emcure's brand ambassador. In 2014, Blackstone sold its 13% stake in Emcure to

Bain Capital Bain Capital, LP is an American Investment company, private investment firm based in Boston, Massachusetts, Boston, Massachusetts, with around $185 billion of assets under management. It specializes in private equity, venture capital, credit, p ...

. In 2021, Emcure demerged its US-based business, including subsidiary Heritage Pharmaceuticals, into a new company called Avet Lifesciences. In 2024, Emcure launched its

initial public offering An initial public offering (IPO) or stock launch is a public offering in which shares of a company are sold to institutional investors and usually also to retail (individual) investors. An IPO is typically underwritten by one or more investm ...

, and listed on NSE and BSE.

Operations

Indian plants

This is the list of manufacturing facilities based in India: *Solid Dosage facility at Hinjawadi - In 2006, Emcure received US FDA approval for its solid dosages facility at

Hinjawadi Hinjawadi (also incorrectly spelt Hinjewadi) is a suburb in Pune, India. It houses the Rajiv Gandhi Infotech Park, a large technology park, tech and business park spread over 2,800 acres, which was built by the Maharashtra Industrial Development ...

, Pune. The plant manufactures solid oral formulations for the international regulated markets, but currently under

FDA warning letter An FDA warning letter is an official message from the United States Food and Drug Administration (FDA) to a manufacturer or other organization that has violated some rule in a federally regulated activity. The FDA defines an FDA warning letter as: ...

*Small volume parenteral facility at Hinjawadi - US FDA, UK MHRA approved. Has lyophilization and pfs capability, but currently under

*Oncology injectable facility at Hinjawadi, but currently under

*Solid Orals facilities at

Jammu Jammu () is a city in Indian-administered Jammu and Kashmir (union territory), Jammu and Kashmir in the disputed Kashmir region.The application of the term "administered" to the various regions of Kashmir and a mention of the Kashmir dispute ...

and

Bhosari Bhosari (IAST: Bhosarī), historically known as Bhojapur, is a suburb in the city of Pune, India. It is well known for its cultural and sports activities like Wrestling and Kabaddi. History Bhosari village has a history dating to Gautam Buddha' ...

*API facility at Kurkumbh- US FDA approved *Biotech facility at Hinjawadi * R&D Center at

Gandhinagar Gandhinagar () is the capital of the state of Gujarat in India. Gandhinagar is located approximately 23 km north of Ahmedabad, on the west central point of the industrial corridor between the megacities of Delhi and Mumbai. Gandhinagar ...

and plant at

Sanand Sanand is a city and a municipality in Ahmedabad district in the Indian States and territories of India, state of Gujarat. It is a major industrial hub of Western India, with manufacturing plants of major domestic and foreign companies. History ...

Ahmedabad Ahmedabad ( ), also spelled Amdavad (), is the most populous city in the Indian state of Gujarat. It is the administrative headquarters of the Ahmedabad district and the seat of the Gujarat High Court. Ahmedabad's population of 5,570,585 ...

.- Sanand facility is

US FDA The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food ...

approved

US plant

USA - The company has a manufacturing facility and R&D center in

East Brunswick, New Jersey East Brunswick is a Township (New Jersey), township in Middlesex County, New Jersey, Middlesex County, in the U.S. state of New Jersey. The suburban bedroom community is part of the New York metropolitan area and is located on the southern sho ...

, USA.

AIDS initiative

Emcure runs the "Let's fight AIDS together" initiative and supplies

antiretroviral The management of HIV/AIDS normally includes the use of multiple antiretroviral drugs as a strategy to control HIV infection. There are several classes of antiretroviral agents that act on different stages of the HIV life-cycle. The use of mu ...

drugs to Africa, Asia Pacific and CIS. As a part of its

corporate social responsibility Corporate social responsibility (CSR) or corporate social impact is a form of international private business industry self-regulation, self-regulation which aims to contribute to societal goals of a philanthropy, philanthropic, activist, or chari ...

, it supports 'Taal', a pharmacy for HIV/AIDS patients run by HIV/AIDS patients.

Controversies and recalls

In 2016, two former executives of Heritage Pharmaceuticals, an erstwhile division of Emcure, were among multiple entities charged by the

United States Department of Justice The United States Department of Justice (DOJ), also known as the Justice Department, is a United States federal executive departments, federal executive department of the U.S. government that oversees the domestic enforcement of Law of the Unite ...

(DOJ) with

price fixing Price fixing is an anticompetitive agreement between participants on the same side in a market to buy or sell a product, service, or commodity only at a fixed price, or maintain the market conditions such that the price is maintained at a given ...

an antibiotic and an antidiabetic drug. In 2019, the company entered into a

deferred prosecution agreement A deferred prosecution agreement (DPA), which is very similar to a non-prosecution agreement (NPA), is a voluntary alternative to adjudication in which a prosecutor agrees to grant amnesty in exchange for the defendant agreeing to fulfill certain ...

with the DOJ. Under the terms of the settlement, Heritage agreed to pay over $7 million in penalty to the DOJ's Civil Division. In 2022, HDT Bio Corp alleged that Emcure (through its subsidiary Gennova) stole the trade secrets of COVID-19 vaccine production in breach of its contract. The lawsuit was dismissed in 2024. In 2016, the USFDA gave a warning letter to Emcure for data integrity problems at Emcure plants. In 2010,

Pfizer Pfizer Inc. ( ) is an American Multinational corporation, multinational Pharmaceutical industry, pharmaceutical and biotechnology corporation headquartered at The Spiral (New York City), The Spiral in Manhattan, New York City. Founded in 184 ...

recalled three batches of an anti-bacterial product from the US market due to presence of ''Bacillus anthracis'', ''Penicillium chrysogenum'' & ''E. coli'' in some samples. Teva recalled several batches of two products due to white tablets showing presence of ''Yersinia pestis'' in 2011. In 2022, Maharashtra FDA issued a circular to recall all the injections (500 mg /10 ml) manufactured by Emcure Pharmaceuticals, from across the country. In 2019, two injected drugs manufactured by Emcure were recalled because of microbial contamination. The drugs were both manufactured by Emcure Pharmaceuticals but were distributed in the US by Heritage Pharmaceuticals (now renamed Avet).FDA asks Emcure to recall contaminated injectable drugs
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References

External links

Emcure website
{{Authority control Manufacturing companies based in Pune Pharmaceutical companies of India Pharmaceutical companies established in 1983 Indian companies established in 1983 Indian brands 1983 establishments in Maharashtra Bain Capital companies Companies listed on the National Stock Exchange of India Companies listed on the Bombay Stock Exchange 2024 initial public offerings