Einar Hammarsten
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Einar Hammarsten (4 January 1889 in
Norrköping Norrköping ( , ) is a city in the province of Östergötland in eastern Sweden and the seat of Norrköping Municipality, Östergötland County, about 160 km southwest of the national capital Stockholm, 40 km east of county seat Lin ...
- 16 February 1968 in
Solna Solna ( or , ), also known as Solna Municipality, is a municipality in central Stockholm County, Sweden, located just north of Stockholm City Centre. Its seat is located in the town of Solna, which is a part of the Stockholm urban area. Solna i ...
) was a Swedish physician and professor of pharmacy and chemistry at the
Karolinska Institute The Karolinska Institute (KI; ; sometimes known as the (Royal) Caroline Institute in English) is a research-led medical university in Solna within the Stockholm urban area of Sweden and one of the foremost medical research institutes globally ...
from 1928 to 1957. His area of research was the chemistry of the
cell nucleus The cell nucleus (; : nuclei) is a membrane-bound organelle found in eukaryote, eukaryotic cell (biology), cells. Eukaryotic cells usually have a single nucleus, but a few cell types, such as mammalian red blood cells, have #Anucleated_cells, ...
, in particular
nucleic acid Nucleic acids are large biomolecules that are crucial in all cells and viruses. They are composed of nucleotides, which are the monomer components: a pentose, 5-carbon sugar, a phosphate group and a nitrogenous base. The two main classes of nuclei ...
s.


Career

Hammarsten was the first to discover that
RNA Ribonucleic acid (RNA) is a polymeric molecule that is essential for most biological functions, either by performing the function itself (non-coding RNA) or by forming a template for the production of proteins (messenger RNA). RNA and deoxyrib ...
, at that time called the
tetranucleotide Nucleotides are organic molecules composed of a nitrogenous base, a pentose sugar and a phosphate. They serve as monomeric units of the nucleic acid polymers – deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), both of which are essent ...
of yeast nucleic acid, is present in animal organs, or more specifically in the
pancreas The pancreas (plural pancreases, or pancreata) is an Organ (anatomy), organ of the Digestion, digestive system and endocrine system of vertebrates. In humans, it is located in the abdominal cavity, abdomen behind the stomach and functions as a ...
. Before Hammarsten's discovery, only
guanylic acid Guanosine monophosphate (GMP), also known as 5′-guanidylic acid or guanylic acid (conjugate acid, conjugate base guanylate), is a nucleotide that is used as a monomer in RNA. It is an ester of phosphoric acid with the nucleoside guanosine. GMP c ...
had been found there. His doctoral dissertation in 1924 was concerned with purification of
DNA Deoxyribonucleic acid (; DNA) is a polymer composed of two polynucleotide chains that coil around each other to form a double helix. The polymer carries genetic instructions for the development, functioning, growth and reproduction of al ...
, at the time called thymonucleic acid, its
ionization Ionization or ionisation is the process by which an atom or a molecule acquires a negative or positive Electric charge, charge by gaining or losing electrons, often in conjunction with other chemical changes. The resulting electrically charged at ...
and
osmotic pressure Osmotic pressure is the minimum pressure which needs to be applied to a Solution (chemistry), solution to prevent the inward flow of its pure solvent across a semipermeable membrane. It is also defined as the measure of the tendency of a soluti ...
. Hammarsten was elected to the
Royal Swedish Academy of Sciences The Royal Swedish Academy of Sciences () is one of the Swedish Royal Academies, royal academies of Sweden. Founded on 2 June 1739, it is an independent, non-governmental scientific organization that takes special responsibility for promoting nat ...
in 1937. He was a member of the
Nobel Committee for Physiology or Medicine The Nobel Committee for Physiology or Medicine is the Nobel Committee responsible for proposing laureates for the Nobel Prize in Physiology or Medicine.
, and was himself nominated for a
Nobel Prize in Physiology or Medicine The Nobel Prize in Physiology or Medicine () is awarded yearly by the Nobel Assembly at the Karolinska Institute for outstanding discoveries in physiology or medicine. The Nobel Prize is not a single prize, but five separate prizes that, acco ...
in 1941. In 1918, Hammarsten married Greta Norrbin, a clinical chemist and medical doctor at the
Karolinska Institute The Karolinska Institute (KI; ; sometimes known as the (Royal) Caroline Institute in English) is a research-led medical university in Solna within the Stockholm urban area of Sweden and one of the foremost medical research institutes globally ...
in Stockholm. As the uncle of the future author and illustrator
Tove Jansson Tove Marika Jansson (; 9 August 1914 – 27 June 2001) was a Swedish-speaking Finnish author, novelist, painter, illustrator and comic strip author. Brought up by artistic parents, Jansson studied art from 1930 to 1938 in Helsinki, Stockholm, ...
, he is credited with inventing the name "
Moomintroll A large number of characters appear in the ''Moomin'' series by Tove Jansson. The original Swedish names are given with the etymologies and word associations suggested by Yvonne Bertills in her 2003 dissertation. Main characters Moomintroll ...
", telling his niece that one of these little monsters lived in the pantry, in an attempt to stop her from pilfering food.


References

{{DEFAULTSORT:Hammarsten, Einar 1889 births 1968 deaths Swedish physicians Swedish chemists Academic staff of the Karolinska Institute Members of the Royal Swedish Academy of Sciences People from Norrköping