2-Ethyl-5-methoxy-''N'',''N''-dimethyltryptamine (EMDT) is a tryptamine derivative which is used in

scientific research The scientific method is an empirical method for acquiring knowledge that has characterized the development of science since at least the 17th century (with notable practitioners in previous centuries; see the article history of scientific ...

. It acts as a selective 5-HT₆ receptor agonist, with a K_i of 16 nM, and was one of the first selective agonists developed for this receptor. EMDT inhibits both short- and long-term memory formation in animal studies, and this effect can be reversed by the selective 5-HT₆ antagonist SB-399,885. Additionally, it is active in the tail suspension test, suggesting that it could be an effective

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References

{{DEFAULTSORT:Ethyl-5-methoxy-N, N-dimethyltryptamine 5-HT6 agonists Tryptamines Phenol ethers Dimethylamino compounds Methoxy compounds

See also

References