''Dysosmobacter'' is a genus of strictly

anaerobic Anaerobic means "living, active, occurring, or existing in the absence of free oxygen", as opposed to aerobic which means "living, active, or occurring only in the presence of oxygen." Anaerobic may also refer to: *Adhesive#Anaerobic, Anaerobic ad ...

, non-spore-forming, rod-shaped bacteria in the family

Oscillospiraceae Oscillospiraceae, also commonly called Ruminococcaceae, is a family of bacteria in the class Clostridia. All Oscillospiraceae are obligate anaerobes. However, members of the family have diverse shapes, with some rod-shaped and others cocci. With ...

, order

Eubacteriales The Eubacteriales are an order of bacteria placed within the class Clostridia. Phylogeny The currently accepted taxonomy is based on the List of Prokaryotic names with Standing in Nomenclature (LPSN) and National Center for Biotechnology Informa ...

. Members of this genus are part of the

gut microbiota Gut microbiota, gut microbiome, or gut flora are the microorganisms, including bacteria, archaea, fungi, and viruses, that live in the digestive tracts of animals. The gastrointestinal metagenome is the aggregate of all the genomes of the g ...

of humans and other animals and are of interest for their potential health-related properties, particularly their production of short-chain fatty acids such as

butyrate The conjugate acids are in :Carboxylic acids. {{Commons category, Carboxylate ions, Carboxylate anions Carbon compounds Anions ...

Taxonomy

The genus ''Dysosmobacter'' was first described in 2020 by Le Roy et al., who isolated the type species, '' Dysosmobacter welbionis'', from the

feces Feces (also known as faeces American and British English spelling differences#ae and oe, or fæces; : faex) are the solid or semi-solid remains of food that was not digested in the small intestine, and has been broken down by bacteria in the ...

of a healthy human subject. Two additional species have since been validly published: * '' Dysosmobacter hominis'', isolated from human feces and described in 2021 by Liu et al. as part of a comprehensive culturomics study of the human gut microbiome. * * '' Dysosmobacter acutus'', isolated from

monkey Monkey is a common name that may refer to most mammals of the infraorder Simiiformes, also known as simians. Traditionally, all animals in the group now known as simians are counted as monkeys except the apes. Thus monkeys, in that sense, co ...

feces and described in 2022 by Li et al.

Etymology

The name ''Dysosmobacter'' derives from the Greek "dysosme" meaning "bad smell" and Latin "bacter" meaning "rod", referring to the strong odor produced by the type strain in culture and its rod-shaped morphology.

Morphology and physiology

Species of ''Dysosmobacter'' are: * Strictly anaerobic * Non-motile * Non-spore-forming * Rod-shaped * Gram-negative in staining, although phylogenetically related to Gram-positive clades They are mesophilic and fermentative, producing SCFAs such as

butyrate The conjugate acids are in :Carboxylic acids. {{Commons category, Carboxylate ions, Carboxylate anions Carbon compounds Anions ...

Ecology

''Dysosmobacter'' species have been isolated from human and non-human primate feces. They are detected in healthy individuals and are considered part of the core

Functional significance

''Dysosmobacter welbionis'' has been shown to exert health-promoting effects in mouse models, including: * Prevention of diet-induced obesity * Improvement of glucose metabolism * Reduction of adipose tissue inflammation These effects were not observed with heat-inactivated cells, indicating that live bacteria are necessary for activity.

Species

As of 2025, the genus ''Dysosmobacter'' includes the following validly published species: * '' Dysosmobacter welbionis'' Le Roy et al. 2020 * '' Dysosmobacter hominis'' Liu et al. 2021 * '' Dysosmobacter acutus'' Li et al. 2022

References

External links

LPSN entry for ''Dysosmobacter''

NCBI Taxonomy Browser: ''Dysosmobacter''

BacDive entry for ''Dysosmobacter welbionis''
{{Taxonbar, from=Q115846915 Oscillospiraceae Bacteria described in 2020 Gut flora bacteria Anaerobes Bacteria genera