Dupuytren
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Guillaume Dupuytren, Baron Dupuytren (, , ; 5 October 1777 – 8 February 1835) was a French
anatomist Anatomy () is the branch of morphology concerned with the study of the internal structure of organisms and their parts. Anatomy is a branch of natural science that deals with the structural organization of living things. It is an old scien ...
and military surgeon. Although he gained much esteem for treating
Napoleon Bonaparte Napoleon Bonaparte (born Napoleone di Buonaparte; 15 August 1769 – 5 May 1821), later known by his regnal name Napoleon I, was a French general and statesman who rose to prominence during the French Revolution and led Military career ...
's
hemorrhoids Hemorrhoids (or haemorrhoids), also known as piles, are vascular structures in the anal canal. In their normal state, they are cushions that help with stool control. They become a disease when swollen or inflamed; the unqualified term ''he ...
he is best known today for his description of Dupuytren's contracture, which is named after him and on which he first operated in 1831 and published in ''
The Lancet ''The Lancet'' is a weekly peer-reviewed general medical journal, founded in England in 1823. It is one of the world's highest-impact academic journals and also one of the oldest medical journals still in publication. The journal publishes ...
'' in 1834.


Birth and education

Guillaume Dupuytren was born in the town of Pierre-Buffière in the present-day department of
Haute-Vienne Haute-Vienne (; , ; Upper Vienne) is a département in the Nouvelle-Aquitaine region in southwest-central France. Named after the Vienne River, it is one of the twelve départements that together constitute Nouvelle-Aquitaine. The prefecture an ...
. He studied
medicine Medicine is the science and Praxis (process), practice of caring for patients, managing the Medical diagnosis, diagnosis, prognosis, Preventive medicine, prevention, therapy, treatment, Palliative care, palliation of their injury or disease, ...
at the newly established École de Médecine in Paris and was appointed prosector, by competition, when only eighteen years of age. His early studies were directed chiefly to
anatomical pathology Anatomical pathology (''Commonwealth'') or anatomic pathology (''U.S.'') is a medical specialty that is concerned with the diagnosis of disease based on the macroscopic, microscopic, biochemical, immunologic and molecular examination ...
. In 1803 he was appointed assistant surgeon at the
Hôtel-Dieu In French-speaking countries, a hôtel-Dieu () was originally a hospital for the poor and needy, run by the Catholic Church. Nowadays these buildings or institutions have either kept their function as a hospital, the one in Paris being the oldest an ...
in Paris, and in 1811 he became professor of operative
surgery Surgery is a medical specialty that uses manual and instrumental techniques to diagnose or treat pathological conditions (e.g., trauma, disease, injury, malignancy), to alter bodily functions (e.g., malabsorption created by bariatric surgery s ...
in succession to Raphael Bienvenu Sabatier. In 1816 he was appointed to the chair of clinical surgery and became head surgeon at the Hôtel-Dieu, a post he held until his death. He is buried in the
Père Lachaise Cemetery Père Lachaise Cemetery (, , formerly , ) is the largest cemetery in Paris, France, at . With more than 3.5 million visitors annually, it is the most visited necropolis in the world. Buried at Père Lachaise are many famous figures in the ...
.


Practice

Dupuytren visited the Hôtel-Dieu morning and evening, each time performing several operations, lectured to vast throngs of students, gave advice to his outpatients and fulfilled the duties consequent upon one of the largest practices of modern times. By his indefatigable activity he amassed a fortune, the bulk of which he bequeathed to his daughter, with the deduction of considerable sums for the endowment of the anatomical chair in the École de Médecine and the establishment of a benevolent institution for distressed physicians. The most important of Dupuytren's writings is his ''Treatise on Accidental Anus'', in which he applied the principles laid down by John Hunter. In his operations he was remarkable for his skill and dexterity and for his great readiness of resource. Dupuytren was one of the first surgeons to drain a
brain abscess The brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals. It consists of nervous tissue and is typically located in the head ( cephalization), usually near organs for special sense ...
successfully using
trepanation Trepanning, also known as trepanation, trephination, trephining or making a burr hole (the verb ''trepan'' derives from Old French from Medieval Latin from Ancient Greek, Greek , literally "borer, auger"), is a surgical intervention in which a ...
, in which a hole is cut in the skull, and he also used the method to treat
seizure A seizure is a sudden, brief disruption of brain activity caused by abnormal, excessive, or synchronous neuronal firing. Depending on the regions of the brain involved, seizures can lead to changes in movement, sensation, behavior, awareness, o ...
s. He claimed credit for originally describing melanoma and claimed Laennec stole the idea from his lectures. He reported a case of breast cancer spontaneous remission in which, after the patient refused surgery, the tumour becoming enlarged, rupturing and becoming infected, it began to shrink and disappeared after a few weeks. He died in Paris and there with his bequest established the Musée Dupuytren. He was a brilliant teacher, an astute diagnostician and a gifted surgeon. On the other hand, he was extremely critical of students and colleagues who failed to live up to his exacting professional standards. This, along with his desire to be the best of the best, won him numerous critics, not all of them objective. He was described by such colourful epithets as 'The Brigand of Hôtel-Dieu' by Jacques Lisfranc and 'First among surgeons, least among men' by
Pierre-François Percy Pierre-François Percy (28 October 1754 – 18 February 1825) was a French medical doctor and surgeon. He was surgeon-in-chief of Napoleon's ''Grande Armée'' during the Napoleonic campaigns in Germany and Poland, and present at the Battles of B ...
.


In fiction

*The surgeon Desplein in Balzac's short story 'The Atheist's Mass' is based on Dupuytren. *Dupuytren's success at draining a cerebral abscess is referred to in
Gustave Flaubert Gustave Flaubert ( , ; ; 12 December 1821 – 8 May 1880) was a French novelist. He has been considered the leading exponent of literary realism in his country and abroad. According to the literary theorist Kornelije Kvas, "in Flaubert, realis ...
's ''
Madame Bovary ''Madame Bovary: Provincial Manners'' (; ), commonly known as simply ''Madame Bovary'', is the début novel by France, French writer Gustave Flaubert, originally published in 1856 and 1857. The eponymous character, Emma Bovary, lives beyond he ...
'': "not Dupuytren, about to open up an abscess through a thick encephalic layer" (Part Two, Chapter 11). *Reference is made in
Victor Hugo Victor-Marie Hugo, vicomte Hugo (; 26 February 1802 – 22 May 1885) was a French Romanticism, Romantic author, poet, essayist, playwright, journalist, human rights activist and politician. His most famous works are the novels ''The Hunchbac ...
's ''
Les Misérables ''Les Misérables'' (, ) is a 19th-century French literature, French Epic (genre), epic historical fiction, historical novel by Victor Hugo, first published on 31 March 1862, that is considered one of the greatest novels of the 19th century. '' ...
'': "Dupuytren and Recamier entered into a quarrel in the amphitheatre of the School of Medicine, and threatened each other with their fists on the subject of the divinity of Jesus Christ."Excerpt From: Hugo, Victor. "Les Misérables." Bookbyte Digital. iBooks. * In Diana Gabaldon's fifth book of the Outlander series, ''The Fiery Cross'', pp. 1227–1229, Claire balances her future knowledge with current medical notes since the Baron Dupuytren has yet to be born. *
Stephen Maturin Stephen Maturin () is a fictional character in the Aubrey–Maturin series of novels by Patrick O'Brian. The series portrays his career as a physician, naturalist and spy in the Royal Navy during the Napoleonic Wars, and the long pursuit of ...
of the
Aubrey–Maturin series The Aubrey–Maturin series is a sequence of nautical historical novels—20 completed and one unfinished—by English author Patrick O'Brian, set during the Napoleonic Wars and centring on the friendship between Captain Jack Aubrey of the R ...
received some of his medical training in Paris, conceding to have "dissected with Dupuytren" while there.


References


Sources

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External links


Catholic Encyclopedia article


WhoNamedIt.

History of Surgeons – surgeons.org.uk
On the injuries and diseases of bones by Guillaume Dupuytren
(1847)
Lesions of the Vascular System, Diseases of the Rectum, and other surgical complaints by Guillaume Dupuytren
(1854) {{DEFAULTSORT:Dupuytren, Guillaume 1777 births 1835 deaths People from Haute-Vienne French surgeons French anatomists 19th-century French physicians 18th-century French physicians French pathologists French military doctors Members of the French Academy of Sciences Burials at Père Lachaise Cemetery