De novo (Latin, , used in English to mean 'from the beginning', 'anew') may refer to:
Science and computers
*
''De novo'' mutation, a new germline mutation not inherited from either parent
* ''De novo''
protein design, the creation of a protein sequence that is not based on existing, natural sequences
*
''De novo'' protein structure prediction, the prediction of a protein's 3D structure, based only on its sequence
*
''De novo'' synthesis of complex molecules from simple molecules in chemistry
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''De novo'' transcriptome assembly, the method of creating a transcriptome without a reference genome, using
de novo sequence assembly
*
''De novo'' gene birth, the emergence of genes from non-coding sequence
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''De novo'' domestication, the domestication of new species for human use
* ''De novo'' assembly in
genomics
Genomics is an interdisciplinary field of molecular biology focusing on the structure, function, evolution, mapping, and editing of genomes. A genome is an organism's complete set of DNA, including all of its genes as well as its hierarchical, ...
* ''De Novo'' classification, a pathway to classify new medical devices provided by the US
Federal Food, Drug, and Cosmetic Act
The United States Federal Food, Drug, and Cosmetic Act (abbreviated as FFDCA, FDCA, or FD&C) is a set of laws passed by the United States Congress in 1938 giving authority to the U.S. Food and Drug Administration (FDA) to oversee the food safety ...
* Denovo, a supercomputer project that simulates nuclear reactions; see
Other
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''De novo'' review, an appellate standard of review for legal issues
*
Trial ''de novo'', or a new trial in the legal system
* ''De novo'' bank, a
state bank
In Australia and the United States, a state bank in a federated state is usually a financial institution that is chartered by the government of that state, as opposed to one regulated at the federal or national level.
In British English, the ter ...
that has been in operation for five years or less
* De Novo, a
public housing estate in Kai Tak, Hong Kong
*
Denovo (band), a 1980s Italian new wave group
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Latin words and phrases