DOB-NDEPA is a
chemical compound
A chemical compound is a chemical substance composed of many identical molecules (or molecular entities) containing atoms from more than one chemical element held together by chemical bonds. A molecule consisting of atoms of only one element ...
of the
phenethylamine
Phenethylamine (PEA) is an organic compound, natural monoamine alkaloid, and trace amine, which acts as a central nervous system stimulant in humans. In the brain, phenethylamine regulates monoamine neurotransmission by binding to trace ami ...
,
DOx, and
NDEPA
Partial or simplified ergolines and lysergamides are analogues of ergolines and lysergamides like LSD in which one or more atoms or bonds, for instance within the ergoline ring system, have been removed. Additional substitutions may also be adde ...
families.
It is the ''N''-(''N'',''N''-diethylpropylamide) (NDEPA)
derivative
In mathematics, the derivative is a fundamental tool that quantifies the sensitivity to change of a function's output with respect to its input. The derivative of a function of a single variable at a chosen input value, when it exists, is t ...
of the
psychedelic drug
Psychedelics are a subclass of hallucinogenic drugs whose primary effect is to trigger non-ordinary mental states (known as psychedelic experiences or "trips") and a perceived "expansion of consciousness". Also referred to as classic halluc ...
DOB
DOB or Dob often refers to date of birth.
DOB or Dob may also refer to:
Biochemistry
* 2,5-dimethoxy-4-bromoamphetamine, Bromo-DMA, a psychedelic drug
** Meta-DOB, related substance
** Methyl-DOB, related substance
* HLA-DOB, human gene
Organiz ...
.
The drug can also be thought of as a derivative of DOB with an
LSD
Lysergic acid diethylamide, commonly known as LSD (from German ; often referred to as acid or lucy), is a semisynthetic, hallucinogenic compound derived from ergot, known for its powerful psychological effects and serotonergic activity. I ...
-like ''N'',''N''-diethylamide
moiety
Moiety may refer to:
__NOTOC__ Anthropology
* Moiety (kinship), either of two groups into which a society is divided
** A division of society in the Iroquois societal structure in North America
** An Australian Aboriginal kinship group
** Native Ha ...
.
A
quantitative structure–activity relationship
Quantitative structure–activity relationship models (QSAR models) are regression or classification models used in the chemical and biological sciences and engineering. Like other regression models, QSAR regression models relate a set of "predi ...
(QSAR) predicted that DOB-NDEPA would bind with high
affinity
Affinity may refer to:
Commerce, finance and law
* Affinity (law), kinship by marriage
* Affinity analysis, a market research and business management technique
* Affinity Credit Union, a Saskatchewan-based credit union
* Affinity Equity Pa ...
to the
serotonin
Serotonin (), also known as 5-hydroxytryptamine (5-HT), is a monoamine neurotransmitter with a wide range of functions in both the central nervous system (CNS) and also peripheral tissues. It is involved in mood, cognition, reward, learning, ...
5-HT2A receptor.
Its predicted affinity (K
i) was 4.6nM.
DOB-NDEPA was first described in the
scientific literature
Scientific literature encompasses a vast body of academic papers that spans various disciplines within the natural and social sciences. It primarily consists of academic papers that present original empirical research and theoretical ...
by 1999.
See also
*
Substituted methoxyphenethylamine
Methoxyphenethylamines (MPEAs), as well as methoxyamphetamines (MAs) in the case of the amphetamine (α-methylphenethylamine) homologues, are substituted phenethylamines with one or more methoxy groups. In some cases, one or more of the methoxy ...
*
Partial lysergamide
Partial or simplified ergolines and lysergamides are analogues of ergolines and lysergamides like LSD in which one or more atoms or bonds, for instance within the ergoline ring system, have been removed. Additional substitutions may also be ad ...
*
DOI-NDEPA
DOI-NDEPA is a chemical compound of the phenethylamine, DOx, and NDEPA families. It is the ''N''-(''N'',''N''-diethylpropylamide) (NDEPA) derivative of the psychedelic drug DOI. The drug can also be thought of as a derivative of DOI with an LSD ...
*
DOTFM-NDEPA
DOTFM-NDEPA is a chemical compound of the phenethylamine, DOx, and NDEPA families. It is the ''N''-(''N'',''N''-diethylpropylamide) (NDEPA) derivative of the psychedelic drug DOTFM. The drug can also be thought of as a derivative of DOTFM with ...
*
25D-NM-NDEAOP
25D-NM-NDEAOP, or 25D-NM-NDEPA, is a chemical compound of the substituted phenethylamine, phenethylamine and 2C (psychedelics), 2C families. It is a partial lysergamide, simplified or partial lysergamide and is a chemical derivative, derivative o ...
*
''N''-DEAOP-NMPEA
*
DEMPDHPCA-2C-D
DEMPDHPCA-2C-D is a possible serotonergic psychedelic of the phenethylamine and 2C families. It is a cyclized phenethylamine and a partial or simplified lysergamide. More specifically, the compound is a derivative of 2C-D in which the β positi ...
References
Amides
Bromobenzene derivatives
Diethylamino compounds
DOx (psychedelics)
Partial ergolines
Propyl compounds
Secondary amines
{{Hallucinogen-stub