''N'',''N''-Diallyltryptamine (DALT) is a
tryptamine
Tryptamine is an indolamine metabolite of the essential amino acid tryptophan. The chemical structure is defined by an indole—a fused benzene and pyrrole ring, and a 2-aminoethyl group at the second carbon (third aromatic atom, with the firs ...
derivative
In mathematics, the derivative is a fundamental tool that quantifies the sensitivity to change of a function's output with respect to its input. The derivative of a function of a single variable at a chosen input value, when it exists, is t ...
which has been identified as a new psychoactive substance.
It has been used as an intermediate in the preparation of
radiolabeled diethyltryptamine
DET, also known under its chemical name ''N'',''N''-diethyltryptamine and as T-9, is a psychedelic drug closely related to DMT and 4-HO-DET.
DET, alongside DMT, was placed into the UN Schedule 1 list of illegal drugs in the 1970s, and is unco ...
.
Use and effects
According to
Alexander Shulgin
Alexander Theodore "Sasha" Shulgin (June 17, 1925 – June 2, 2014) was an American biochemist, broad researcher of synthetic psychoactive compounds, and author of works regarding these, who independently explored the organic chemistry and ph ...
in ''
TiHKAL
''TiHKAL: The Continuation'' is a 1997 book written by Alexander Shulgin and Ann Shulgin about a family of psychoactive drugs known as tryptamines. A sequel to '' PiHKAL: A Chemical Love Story'', ''TiHKAL'' is an acronym that stands for "Trypt ...
'', the dosage of DALT is >40mg
orally and its
duration is unknown.
Its effects have not been described.
According to
Stephen Szara and colleagues however, DALT and other extended ''N'',''N''-dialkyltryptamines produce similar effects to
dimethyltryptamine
Dimethyltryptamine (DMT), also known as ''N'',''N''-dimethyltryptamine (''N'',''N''-DMT), is a Psychedelic drug, serotonergic hallucinogen and Investigational New Drug, investigational drug of the substituted tryptamine, tryptamine family tha ...
(DMT) but are longer-lasting, with durations of up to 3hours.
Pharmacology
The
receptor
Receptor may refer to:
* Sensory receptor, in physiology, any neurite structure that, on receiving environmental stimuli, produces an informative nerve impulse
*Receptor (biochemistry), in biochemistry, a protein molecule that receives and respond ...
interactions of DALT have been studied.
The drug produces the
head-twitch response
The head-twitch response (HTR), also sometimes known as wet dog shakes (WDS) in rats, is a rapid side-to-side head movement that occurs in mice and rats in association with serotonin 5-HT2A receptor activation. Serotonergic psychedelics like lys ...
, a behavioral proxy of
psychedelic
Psychedelics are a subclass of hallucinogenic drugs whose primary effect is to trigger non-ordinary mental states (known as psychedelic experiences or "trips") and a perceived "expansion of consciousness". Also referred to as classic halluci ...
effects, in rodents.
History
DALT was first described in the
scientific literature
Scientific literature encompasses a vast body of academic papers that spans various disciplines within the natural and social sciences. It primarily consists of academic papers that present original empirical research and theoretical ...
by
Stephen Szara and colleagues by 1962.
See also
*
Substituted tryptamine
Substituted tryptamines, or simply tryptamines, also known as serotonin analogues (i.e., 5-hydroxytryptamine analogues), are organic compounds which may be thought of as being derived from tryptamine itself. The molecular structures of all trypt ...
*
4-HO-DALT
4-HO-DALT, also known as 4-hydroxy-''N'',''N''-diallyltryptamine or as dalocin, is a serotonin receptor agonist and serotonergic psychedelic of the tryptamine and 4-hydroxytryptamine families.
It binds to many of the serotonin receptors, includ ...
*
4-AcO-DALT
4-Acetyloxy-''N,N''-diallyltryptamine (or 4-AcO-DALT) is a tryptamine derivative (chemistry), derivative. It has been sold as a designer drug, but little other information is available. It was first officially identified in seized drug samples in ...
*
5-MeO-DALT
5-MeO-DALT, also known as ''N'',''N''-diallyl-5-methoxytryptamine, or as foxtrot, is a psychedelic drug of the substituted tryptamine, tryptamine and substituted 5-methoxytryptamine, 5-methoxytryptamine families. It was first chemical synthesis, ...
References
External links
DALT - Isomer DesignThe Big & Dandy DALT (N,N-Diallyltryptamine) Thread - BluelightDALT - TiHKAL - Isomer Design
{{Tryptamines
Adrenergic receptor modulators
N,N-Dialkyltryptamines
Designer drugs
Diallylamino compounds
Dopamine receptor modulators
Entheogens
Psychedelic tryptamines
Serotonin receptor modulators
Sigma receptor modulators