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{{Infobox company , , name = Cyclacel Pharmaceuticals, Inc. , logo = Cyclacel.png , type = Public , traded_as = {{NASDAQ, CYCC , foundation = 1997 , location =
Berkeley Heights, New Jersey Berkeley Heights is a township in Union County, New Jersey, United States. A commuter town in northern- central New Jersey, the township is nestled within the Raritan Valley region in the New York metropolitan area. As of the 2010 United Stat ...
, U.S. , key_people = Spiro Rombotis, CEO
David P. Lane, PhD David (; , "beloved one") (traditional spelling), , ''Dāwūd''; grc-koi, Δαυΐδ, Dauíd; la, Davidus, David; gez , ዳዊት, ''Dawit''; xcl, Դաւիթ, ''Dawitʿ''; cu, Давíдъ, ''Davidŭ''; possibly meaning "beloved one". w ...
, founder
Paul McBarron, EVP, Finance & COO
Mark Kirschbaum, MD, CMO , industry =
Biotechnology Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used b ...
, products = Fadraciclib (formerly CYC065),
CYC140 , net_income = {{loss US$ 19.1 million (2021) , num_employees = 17 (2022) , homepage = http://www.cyclacel.com Cyclacel Pharmaceuticals Inc. is a
biotechnology Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used b ...
firm based in
Berkeley Heights, New Jersey Berkeley Heights is a township in Union County, New Jersey, United States. A commuter town in northern- central New Jersey, the township is nestled within the Raritan Valley region in the New York metropolitan area. As of the 2010 United Stat ...
and Dundee, Scotland, developing cancer treatments. Cyclacel was founded in 1996 by David Lane, PhD.


Company overview

Cyclacel Pharmaceuticals, Inc. is a clinical-stage, biopharmaceutical company developing innovative cancer medicines based on cell cycle, transcriptional regulation and mitosis biology. The transcriptional regulation program is evaluating fadraciclib, a CDK2/9 inhibitor, and the anti-mitotic program CYC140, a PLK1 inhibitor, in patients with both solid tumors and hematological malignancies. Cyclacel’s strategy is to build a diversified biopharmaceutical business based on a pipeline of novel drug candidates addressing oncology and hematology indications. For additional information, please visit www.cyclacel.com. Sir David Lane, PhD, a recognized leader in the field of tumor suppressor biology, who discovered the p53 protein, founded the company in 1996. In 1999, Cyclacel Pharmaceuticals was joined by David Glover, PhD, a recognized leader in the mechanism of mitosis or cell division, who discovered, among other cell cycle targets, the mitotic kinases, Polo and Aurora, enzymes that act in the mitosis phase of the cell cycle. Companies listed on the Nasdaq Pharmaceutical companies based in New Jersey Pharmaceutical companies of Scotland Companies based in Dundee Science and technology in Dundee