R05C Expectorants, excluding combinations with cough suppressants

R05CA
Expectorant Mucoactive agents are a class of pharmacologic agents that include expectorants, mucolytics, mucoregulators, and mucokinetics that can affect the volume, viscosity, transportation, and composition of mucus or sputum. They often aid in clearing ...
s

:R05CA01 Tyloxapol :R05CA02

Potassium iodide Potassium iodide is a chemical compound, medication, and dietary supplement. It is a medication used for treating hyperthyroidism, in radiation emergencies, and for protecting the thyroid gland when certain types of radiopharmaceuticals are u ...

:R05CA03

Guaifenesin Guaifenesin, also known as glyceryl guaiacolate, sold under the brand name Mucinex, among others, is an expectorant medication taken by mouth and marketed as an aid to eliminate sputum from the respiratory tract. Chemically, it is an ether of ...

:R05CA04

Ipecacuanha Ipecacuanha may refer to: * a synonym of '' Carapichea'', a genus of flowering plants in the family Rubiaceae * the common name of ''Carapichea ipecacuanha'', a species of flowering plant in the family Rubiaceae, the roots of which were used to mak ...

:R05CA05 Altheae radix :R05CA06 Senega :R05CA07 Antimony pentasulfide :R05CA08

Creosote Creosote is a category of carbonaceous chemicals formed by the distillation of various tars and pyrolysis of plant-derived material, such as wood, or fossil fuel. They are typically used as preservatives or antiseptics. Some creosote types w ...

:R05CA09 Guaiacolsulfonate :R05CA10 Combinations :R05CA11

Levoverbenone Levoverbenone is an expectorant. It is the (−)-isomer of verbenone Verbenone is a natural organic compound classified as a terpene that is found naturally in a variety of plants. The chemical has a pleasant characteristic odor. Besides bein ...

:R05CA12 Hederae helicis folium :R05CA13

Cineole Eucalyptol (also called cineole) is a monoterpenoid colorless liquid, and a bicyclic ether. It has a fresh camphor-like odor and a spicy, cooling taste. It is insoluble in water, but miscible with organic solvents. Eucalyptol makes up about ...

R05CB
Mucolytic Mucoactive agents are a class of pharmacologic agents that include expectorants, mucolytics, mucoregulators, and mucokinetics that can affect the volume, viscosity, transportation, and composition of mucus or sputum. They often aid in clearing ...
s

:R05CB01

Acetylcysteine ''N''-acetylcysteine, also known as Acetylcysteine and NAC, is a mucolytics that is used to treat paracetamol (acetaminophen) overdose and to loosen thick mucus in individuals with chronic bronchopulmonary disorders, such as pneumonia and ...

:R05CB02

Bromhexine Bromhexine is a mucolytic drug used in the treatment of respiratory disorders associated with viscid or excessive mucus. It was developed in the research laboratory of Boehringer Ingelheim in the late 1950s as an active ingredient for pharmaceut ...

:R05CB03

Carbocisteine Carbocisteine, also called carbocysteine, is a mucolytic that reduces the viscosity of sputum and so can be used to help relieve the symptoms of chronic obstructive pulmonary disorder (COPD) and bronchiectasis by allowing the sufferer to bring u ...

:R05CB04 Eprazinone :R05CB05

Mesna Mesna, sold under the brand name Mesnex among others, is a medication used in those taking cyclophosphamide or ifosfamide to decrease the risk of hemorrhagic cystitis, bleeding from the bladder. It is used either Oral administration, by mouth or ...

:R05CB06

Ambroxol Ambroxol is a drug that breaks up phlegm, used in the treatment of respiratory diseases associated with viscid or excessive mucus. Ambroxol is often administered as an active ingredient in cough syrup. It was patented in 1966 and came into me ...

:R05CB07 Sobrerol :R05CB08 Domiodol :R05CB09 Letosteine :R05CB10 Combinations :R05CB11 Stepronin :R05CB13

Dornase alfa Dornase alfa, sold under the brand name Pulmozyme, is used for the treatment of cystic fibrosis. It is a recombinant human deoxyribonuclease I (rhDNase), an enzyme which selectively cleaves DNA. Dornase alfa hydrolyzes the DNA present in sputum/ ...

( desoxyribonuclease) :R05CB14 Neltenexine :R05CB15

Erdosteine Erdosteine is a molecule with mucolytic activity. Structurally it is a thioether derivative with two thioether groups. These two functional organosulfur groups contained in the molecule are released following first-pass metabolism with the conver ...

:R05CB16

Mannitol Mannitol is a type of sugar alcohol used as a sweetener and medication. It is used as a low calorie sweetener as it is poorly absorbed by the intestines. As a medication, it is used to decrease pressure in the eyes, as in glaucoma, and to l ...

:QR05CB90 Dembrexine hydrochloride

R05D
Cough suppressant Cold medicines are a group of medicinal, medications taken individually or in Combination drug, combination as a Symptomatic treatment, treatment for the symptoms of the common cold and similar conditions of the upper respiratory tract. The ter ...
s, excluding combinations with expectorants

R05DA Opium alkaloids and derivatives

:R05DA01

Ethylmorphine Ethylmorphine (also known as codethyline, dionine, and ethyl morphine) is an opioid analgesic and antitussive. Side effects Adverse effects are similar to other opioids and include drowsiness, constipation, vertigo, nausea, vomiting, and respirat ...

:R05DA03

Hydrocodone Hydrocodone, also known as dihydrocodeinone, is a semi-synthetic opioid used to treat pain and as a cough suppressant. It is taken by mouth. Typically, it is dispensed as the combination acetaminophen/hydrocodone or ibuprofen/hydrocodone fo ...

:R05DA04

Codeine Codeine is an opiate and prodrug of morphine mainly used to treat pain, coughing, and diarrhea. It is also commonly used as a recreational drug. It is found naturally in the sap of the opium poppy, ''Papaver somniferum''. It is typically use ...

:R05DA05 Opium alkaloids with morphine :R05DA06

Normethadone Normethadone (INN, BAN; brand names Ticarda, Cophylac, Dacartil, Eucopon, Mepidon, Noramidone, Normedon, and others), also known as desmethylmethadone or phenyldimazone, is a synthetic opioid analgesic and antitussive Cold medicines are a ...

:R05DA07

Noscapine Noscapine, also known as narcotine, nectodon, nospen, anarcotine and (archaic) opiane, is a benzylisoquinoline alkaloid of the phthalideisoquinoline structural subgroup, which has been isolated from numerous species of the family Papaveraceae (p ...

:R05DA08

Pholcodine Pholcodine is an opioid cough suppressant (antitussive). It helps suppress unproductive coughs and also has a mild sedative effect, but has little or no analgesic effects. It is also known as morpholinylethylmorphine and homocodeine. Pholcodin ...

:R05DA09

Dextromethorphan Dextromethorphan, sold under the brand name Robitussin among others, is a cough suppressant used in many cough and Common cold, cold medicines. In 2022, the US Food and Drug Administration (FDA) approved the combination dextromethorphan/bupropi ...

:R05DA10

Thebacon Thebacon (INN; pronounced ), or dihydrocodeinone enol acetate, is a semisynthetic opioid that is similar to hydrocodone and is most commonly synthesised from thebaine. Thebacon was invented in Germany in 1924, four years after the first synthe ...

:R05DA11

Dimemorfan Dimemorfan (INN; JAN dimemorfan phosphate; also known as dimemorphan and 3,17-dimethylmorphinan; brand names Astomin, Dastosirr, and Tusben) is an antitussive (cough suppressant) of the morphinan family that is widely used in Japan and is also m ...

:R05DA12

Acetyldihydrocodeine Acetyldihydrocodeine is an opiate derivative discovered in Germany in 1914 and was used as a cough suppressant and analgesic. It is not commonly used, but has activity similar to other opiates. Acetyldihydrocodeine is a very close relative deri ...

:R05DA20 Combinations ''(QR05DA20 Combinations of opium alkaloids and derivatives)'' :QR05DA90

Butorphanol Butorphanol is a morphinan-type synthetic agonist–antagonist opioid analgesic developed by Bristol-Myers. Butorphanol is most closely structurally related to levorphanol. Butorphanol is available as the tartrate salt in injectable, tablet, and ...

R05DB Other cough suppressants

:R05DB01

Benzonatate Benzonatate (), sold under the brand name Tessalon among others, is a medication that is used for the symptomatic relief of cough. Benzonatate is taken oral administration, by mouth. Effects generally begin within 20minutes and last between 3 a ...

:R05DB02 Benproperine :R05DB03 Clobutinol :R05DB04 Isoaminile :R05DB05

Pentoxyverine Pentoxyverine ( rINN) or carbetapentane is an antitussive (cough suppressant) commonly used for cough associated with illnesses like common cold. It is sold over-the-counter as Solotuss, or in combination with other medications, especially decong ...

:R05DB07

Oxolamine Oxolamine is a cough suppressant that is available as a generic drug in many jurisdictions. Oxolamine also has anti-inflammatory activity, which causes a reduction in irritation of the nerve receptors of the respiratory tract. It is mainly used ...

:R05DB09 Oxeladin :R05DB10 Clofedanol :R05DB11

Pipazetate Pipazetate () (brand names Dipect, Lenopect, Selvigon, Theratuss, Toraxan), or pipazethate (), is a 1-azaphenothiazine drug that was briefly marketed as a cough suppressant. It binds to the sigma-1 receptor with an IC50 value of 190 nM. It also ...

:R05DB12 Bibenzonium bromide :R05DB13

Butamirate Butamirate (or brospamin, trade names Acodeen, Codesin, Pertix, Sinecod, Sinecoden, Sinecodix) is a cough suppressant. It has been marketed in Europe and Mexico, but not in the United States. It is sold in the form of lozenges, syrup, tablets, dr ...

:R05DB14

Fedrilate Fedrilate is a centrally acting cough suppressant. It was patented as a mucolytic by UCB in 1971, but was never brought to market in the US. In the Netherlands, it has been marketed as Tussefan and in combination with guaifenesin Guaifenes ...

:R05DB15 Zipeprol :R05DB16 Dibunate :R05DB17 Droxypropine :R05DB18 Prenoxdiazine :R05DB19 Dropropizine :R05DB20 Combinations :R05DB21

Cloperastine Cloperastine ( INN) or cloperastin, in the forms of cloperastine hydrochloride ( JAN) (brand names Hustazol, Nitossil, Seki) and cloperastine fendizoate, is an antitussive and antihistamine that is marketed as a cough suppressant in Japan, Hong K ...

:R05DB22 Meprotixol :R05DB23 Piperidione :R05DB24

Tipepidine Tipepidine (International Nonproprietary Name, INN; also known as tipepidine hibenzate (Japanese Accepted Name, JAN); brand names Asverin, Antupex, Asvelik, Asvex, Bitiodin, Cofdenin A, Hustel, Nodal, and Sotal) is a Organic compound#Synthetic co ...

:R05DB25 Morclofone :R05DB26 Nepinalone :R05DB27

Levodropropizine Levodropropizine is a cough suppressant. It is the levo isomer of dropropizine. It acts as a peripheral antitussive, with no action in the central nervous system. It does not cause side effects such as constipation or respiratory depression whic ...

:R05DB28 Dimethoxanate :R05DB29

Gefapixant Gefapixant, sold under the brand name Lyfnua, is a medication used to treat chronic (long-term) cough. It acts as an antagonist of the P2RX3 receptor. It was authorized for medical use in the European Union in September 2023. Medical uses ...

R05F Cough suppressants and expectorants, combinations

R05FA Opium derivatives and expectorants

:R05FA01 Opium derivatives and mucolytics :R05FA02 Opium derivatives and expectorants

R05FB Other cough suppressants and expectorants

:R05FB01 Cough suppressants and mucolytics :R05FB02 Cough suppressants and expectorants

R05X Other cold preparations

:''Empty group''

References

{{Cough and cold preparations R05