This is a list of

corticosteroid Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones. Two main classes of corticosteroids, glucocorticoids and mineralocorticoids, are invo ...

cyclic

ketal In organic chemistry, an acetal is a functional group with the connectivity . Here, the R groups can be organic fragments (a carbon atom, with arbitrary other atoms attached to that) or hydrogen, while the R' groups must be organic fragments n ...

s, including cyclic ketals (cyclic

acetal In organic chemistry, an acetal is a functional group with the connectivity . Here, the R groups can be organic fragments (a carbon atom, with arbitrary other atoms attached to that) or hydrogen, while the R' groups must be organic fragments n ...

s) of

steroid A steroid is an organic compound with four fused compound, fused rings (designated A, B, C, and D) arranged in a specific molecular configuration. Steroids have two principal biological functions: as important components of cell membranes t ...

glucocorticoid Glucocorticoids (or, less commonly, glucocorticosteroids) are a class of corticosteroids, which are a class of steroid hormones. Glucocorticoids are corticosteroids that bind to the glucocorticoid receptor that is present in almost every vertebra ...

s and

mineralocorticoid Mineralocorticoids are a class of corticosteroids, which in turn are a class of steroid hormones. Mineralocorticoids are produced in the adrenal cortex and influence salt and water balances (electrolyte balance and fluid balance). The primary ...

s. They are almost all C16α,17α cyclic ketals of corticosteroids. One of the most widely used corticosteroid cyclic ketals is

triamcinolone acetonide Triamcinolone acetonide, sold under the brand name Kenalog among others, is a synthetic compound, synthetic corticosteroid medication used topical medication, topically to treat various skin conditions, to relieve the discomfort of mouth sores, ...

, which is the C16α,17α acetonide (cyclic ketone with

acetone Acetone (2-propanone or dimethyl ketone) is an organic compound with the chemical formula, formula . It is the simplest and smallest ketone (). It is a colorless, highly Volatile organic compound, volatile, and flammable liquid with a charact ...

) of triamcinolone. This list mostly does not include esters of corticosteroid cyclic ketals, which are listed

here Here may refer to: Music * ''Here'' (Adrian Belew album), 1994 * ''Here'' (Alicia Keys album), 2016 * ''Here'' (Cal Tjader album), 1979 * ''Here'' (Edward Sharpe album), 2012 * ''Here'' (Idina Menzel album), 2004 * ''Here'' (Merzbow album), ...

instead.

Acetonides

Acetonides (cyclic ketals with

): * Cicortonide * Ciprocinonide (fluocinolone acetonide cyclopropylcarboxylate) * Descinolone acetonide (desoxytriamcinolone acetonide) * Desonide (desfluorotriamcinolone acetonide) * Drocinonide * Fluclorolone acetonide (flucloronide) * Fludroxycortide (flurandrenolide, flurandrenolone) * Flumoxonide *

Flunisolide Flunisolide (marketed as AeroBid among others) is a corticosteroid often prescribed as a treatment for allergic rhinitis. Intranasal corticosteroids are the most effective medication for controlling symptoms. Flunisolide's principal mechanism o ...

Fluocinolone acetonide Fluocinolone acetonide is a fluorinated corticosteroid primarily used in dermatology to reduce skin inflammation and relieve itching. It is a synthetic hydrocortisone derivative. The fluorine substitution at position 9 in the steroid nucleus gr ...

* Fluocinonide (fluocinolone acetonide 21-acetate) * Flupamesone (triamcinolone acetonide metembonate) * Formocortal * Halcinonide * Procinonide (fluocinolone acetonide propionate) * Tralonide *

Triamcinolone acetonide Triamcinolone acetonide, sold under the brand name Kenalog among others, is a synthetic compound, synthetic corticosteroid medication used topical medication, topically to treat various skin conditions, to relieve the discomfort of mouth sores, ...

* Triamcinolone benetonide (triamcinolone acetonide 21-(benzoyl-β-aminoisobutyrate)) * Triamcinolone furetonide (triamcinolone acetonide 21-(2-benzofurancarboxylate)) * Triamcinolone hexacetonide (triamcinolone acetonide 21-tebutate) * Triclonide

Others

Acetophenides

Acetophenide In organic chemistry, acetophenide is a functional group which is composed of the cyclic compound, cyclic ketal of a diol with acetophenone. In pharmaceutical chemistry, it is present in algestone acetophenide (dihydroxyprogesterone acetophenide) a ...

s (cyclic ketals with acetophenone): * Algestone acetophenide (dihydroxyprogesterone acetophenide) * Amcinafide (triamcinolone acetophenide)

Acroleinides

Acroleinides (cyclic ketals with acrolein): * Acrocinonide (triamcinolone acroleinide)

Aminobenzals

Aminobenzals (cyclic ketals with 4-dimethylaminobenzylidene): * Triamcinolone aminobenzal benzamidoisobutyrate (TBI-PAB)

Cyclopentanonides

Cyclopentanonides (cyclic ketals with

cyclopentanone Cyclopentanone is the organic compound with the formula (CH2)4CO. This cyclic ketone is a colorless volatile liquid. Preparation Ketonic decarboxylation of adipic acid gives cyclopentanone. The reaction is conducted at elevated temperatures in t ...

): * Amcinonide (triamcinolone acetate cyclopentanonide)

Pentanonides

Pentanonides (cyclic ketals with 3-pentanone) * Amcinafal (triamcinolone pentanonide)

With butyraldehyde

Cyclic ketals with

butyraldehyde Butyraldehyde, also known as butanal, is an organic compound with the formula CH3(CH2)2CHO. This compound is the aldehyde derivative of butane. It is a colorless flammable liquid with an unpleasant smell. It is miscible with most organic solvents. ...

: * Budesonide * Dexbudesonide * Itrocinonide * Rofleponide

Miscellaneous

* Nicocortonide is a C14α,17α cyclic ketal with crotonaldehyde

References

{{Mineralocorticoid receptor modulators Corticosteroid cyclic ketals Corticosteroids Glucocorticoids