Clavaric acid is a triterpenoid produced by the mushroom ''

Hypholoma sublateritium ''Hypholoma lateritium'', sometimes called brick cap, chestnut mushroom, cinnamon cap, brick top, red woodlover or kuritake, is a fungal species in the genus ''Hypholoma'', which also contains the poisonous species ''Hypholoma fasciculare'' a ...

''. Clavaric acid was discovered by

Merck Research Laboratories Merck & Co., Inc. is an American multinational pharmaceutical company headquartered in Rahway, New Jersey, and is named for Merck Group, founded in Germany in 1668, of whom it was once the American arm. The company does business as Merck Sharp ...

in a random screening of natural extracts. Clavaric acid is a reversible farnesyltransferase inhibitor with an IC₅₀ of 1.3 μM.

References

{{Reflist Lanostanes Triterpenes