Chromone (or 1,4-benzopyrone) is a derivative of benzopyran with a substituted keto group on the

pyran In chemistry, pyran, or oxine, is a six-membered heterocyclic, non-aromatic ring, consisting of five carbon atoms and one oxygen atom and containing two double bonds. The molecular formula is C5H6O. There are two isomers of pyran that differ by th ...

ring. It is an isomer of

coumarin Coumarin () or 2''H''-chromen-2-one is an aromatic organic chemical compound with formula . Its molecule can be described as a benzene molecule with two adjacent hydrogen atoms replaced by a lactone-like chain , forming a second six-membered ...

. Derivatives of chromone are collectively known as ''chromones''. Most, though not all, chromones are also

phenylpropanoid The phenylpropanoids are a diverse family of organic compounds that are synthesized by plants from the amino acids phenylalanine and tyrosine. Their name is derived from the six-carbon, aromatic phenyl group and the three-carbon propene tail of ...

Examples

* 6,7-dimethoxy-2,3-dihydrochromone has been isolated from '' Sarcolobus globosus''. * Eucryphin, a chromone rhamnoside, can be isolated from the bark of ''

Eucryphia cordifolia ''Eucryphia cordifolia'', the ulmo, is a species of tree in the family Cunoniaceae. It is found in Chile and Argentina. It is threatened by logging and habitat loss. The natural habitat is along the Andes Range from 38 to 43°S, and up to ...

''. * Cromolyn (disodium cromoglicate) was found to inhibit antigen challenge as well as stress induced symptoms.HOWELL, J.B. & ALTOUNYAN, R.E. (1967). A double-blind trial of disodium cromoglycate in the treatment of allergic bronchial asthma. Lancet, 2, 539–542
Abstract
/ref> Cromoglicate is used as a

mast cell stabilizer Mast cell stabilizers are medications used to prevent or control certain allergic disorders. They block mast cell degranulation, stabilizing the cell and thereby preventing the release of histamine and related mediators. One suspected pharmac ...

allergic rhinitis Allergic rhinitis, of which the seasonal type is called hay fever, is a type of inflammation in the nose that occurs when the immune system overreacts to allergens in the air. Signs and symptoms include a runny or stuffy nose, sneezing, red, ...

asthma Asthma is a long-term inflammatory disease of the airways of the lungs. It is characterized by variable and recurring symptoms, reversible airflow obstruction, and easily triggered bronchospasms. Symptoms include episodes of wheezing, c ...

and allergic conjunctivitis. * Nedocromil sodium was found to have a somewhat longer half-life than cromolyn; however, production was discontinued in the US in 2008. *

Xanthone Xanthone is an organic compound with the molecular formula O 6H4sub>2CO. It is a white solid. In 1939, xanthone was introduced as an insecticide and it currently finds uses as ovicide for codling moth eggs and as a larvicide. Xanthone is also ...

with a second aromatic ring.

References

External links

* – "4-chromone" *
Synthesis at organic-chemistry.org
{{Phenylpropanoid

Examples

See also

References

External links