Bico Group (previously Cellink) is a
bioconvergence startup
A startup or start-up is a company or project undertaken by an entrepreneur to seek, develop, and validate a scalable business model. While entrepreneurship refers to all new businesses, including self-employment and businesses that never intend t ...
that designs and supplies technologies and services to enhance biology research. It focuses on commercializing technologies for life science research as well as bioprinting, and its products often combine capabilities in
artificial intelligence
Artificial intelligence (AI) is intelligence—perceiving, synthesizing, and inferring information—demonstrated by machines, as opposed to intelligence displayed by animals and humans. Example tasks in which this is done include speech re ...
,
robotics
Robotics is an interdisciplinary branch of computer science and engineering. Robotics involves design, construction, operation, and use of robots. The goal of robotics is to design machines that can help and assist humans. Robotics integrat ...
,
multiomics
Multiomics, multi-omics, integrative omics, "panomics" or "pan-omics" is a biological analysis approach in which the data sets are multiple "omes", such as the genome, proteome, transcriptome, epigenome, metabolome, and microbiome (i.e., a meta ...
, and
diagnostics
Diagnosis is the identification of the nature and cause of a certain phenomenon. Diagnosis is used in many different disciplines, with variations in the use of logic, analytics, and experience, to determine "cause and effect". In systems engineer ...
.
Bico Group (then Cellink) began by producing
bio-ink
Bio-inks are materials used to produce engineered/artificial live tissue using 3D printing. These inks are mostly composed of the cells that are being used, but are often used in tandem with additional materials that envelope the cells. The combi ...
s and
bioprinters for
culturing different cell types to enable applications like
patient-derived implants. Bico Group was the first company to provide a standardized bio-ink product for sale over the internet.
The company has ongoing collaborations with organizations including
AstraZeneca,
MedImmune,
MIT and
Takara Bio
Takara Co., Ltd. (株式会社タカラ) was a Japanese toy company founded in 1955. In March 2006, the company merged with Tomy Co., Ltd. to form Takara Tomy. The Takara motto was 遊びは文化」("playing is culture").
Products Toys
In ...
, and its bioprinters are used for research at
Harvard University
Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher le ...
,
Merck
Merck refers primarily to the German Merck family and three companies founded by the family, including:
* the Merck Group, a German chemical, pharmaceutical and life sciences company founded in 1668
** Merck Serono (known as EMD Serono in the Unite ...
,
Novartis
Novartis AG is a Swiss-American multinational pharmaceutical corporation based in Basel, Switzerland and
Cambridge, Massachusetts, United States (global research).name="novartis.com">https://www.novartis.com/research-development/research-loc ...
, the
U.S. Army,
Toyota
is a Japanese multinational automotive manufacturer headquartered in Toyota City, Aichi, Japan. It was founded by Kiichiro Toyoda and incorporated on . Toyota is one of the largest automobile manufacturers in the world, producing about 10 ...
,
Johnson & Johnson
Johnson & Johnson (J&J) is an American multinational corporation founded in 1886 that develops medical devices, pharmaceuticals, and consumer packaged goods. Its common stock is a component of the Dow Jones Industrial Average and the company i ...
and more.
History
Bico Group was founded as Cellink in 2016 by
Erik Gatenholm, the company's chief executive, Héctor Martinez, the company's CTO and Gusten Danielsson, the company's CFO.
They developed and sold the world's first universally compatible bio-ink to simplify bioprinting for academics and pharmaceutical companies who were, at that time, mixing their own biomaterial in-house.
The company released its first bioprinter to test the market in 2015, and continued designing additional bio-inks to support more specialized applications in bioprinting.
Ten months after it was founded, Cellink was listed publicly on the
Nasdaq exchange First North.
At its
IPO
An initial public offering (IPO) or stock launch is a public offering in which shares of a company are sold to institutional investors and usually also to retail (individual) investors. An IPO is typically underwritten by one or more investment ...
, shares were
oversubscribed by 1070 percent.
As the company's technology makes it possible to print tissues such as skin, liver, and cartilage, its technology also allows printing fully functional cancer tumors which can be used to develop new cancer treatment. In 2018, Cellink received a $2.5 million grant from the EU to fund its TumorPrint project.
In 2017, the company was described as "a world leader in bioprinting". It established a United States headquarters in
Boston
Boston (), officially the City of Boston, is the state capital and most populous city of the Commonwealth of Massachusetts, as well as the cultural and financial center of the New England region of the United States. It is the 24th- mo ...
the same year.
In January 2018, Cellink announced a collaboration with Ctibiotech to boost 3D bioprinting technology for cancer research.
The company's revenue totaled $4.88 million in 2018.
As of February 2019, its products are used by more than 600 labs in more than 50 countries.
In August 2021, Cellink underwent a corporate transformation and changed name to BICO, while keeping the Cellink name for their bioprinting business.
Bico Group acquired German biotechnology company Cytena in August 2019 for a purchase price of $33.8 million.
Bico Group acquired Scienion, a global precision dispensing company, in 2020 for $94.8 million, along with its subsidiary Cellenion.
Bico Group transitioned to a
bioconvergence company in 2020, expanding its focus from
bioprinting
Three dimensional (3D) bioprinting is the utilization of 3D printing–like techniques to combine cells, growth factors, and/or biomaterials to fabricate biomedical parts, often with the aim of imitating natural tissue characteristics. Generally, 3 ...
to broader
life sciences
This list of life sciences comprises the branches of science that involve the scientific study of life – such as microorganisms, plants, and animals including human beings. This science is one of the two major branches of natural science, the ...
technology and industrial solutions.
The company develops and markets products that enable researchers to culture cells in 3D, perform
high-throughput drug screening, and print human tissues and organs for use in medical, pharmaceutical and cosmetic applications.
In May 2021, Bico Group acquired German 3D microfabrication company Nanoscribe for $70.6 million as well as the US-based contract research company Visikol for $7.5 million.
In December 2021, Bico Group acquired the San Diego life-science automaton company
Biosero for $165 million.
In August 2023, after investing too much in marketing and not in R&D, the CEO leaves the company
[https://bico.com/single-press-release/?id=a4840f28-1823-4bab-a42e-db813d67e11f]
Products
The bio-ink produced by the company contains
cellulose
Cellulose is an organic compound with the formula , a polysaccharide consisting of a linear chain of several hundred to many thousands of β(1→4) linked D-glucose units. Cellulose is an important structural component of the primary cell wall ...
and
alginate, locally sourced from trees in Sweden and seaweed from the Norwegian Sea, respectively.
Cellink's bio-ink technology was developed at
Chalmers University
Chalmers University of Technology ( sv, Chalmers tekniska högskola, often shortened to Chalmers) is a Swedish university located in Gothenburg that conducts research and education in technology and natural sciences at a high international leve ...
.
References
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Emerging technologies
3D printer companies
Companies based in Massachusetts
Computer companies established in 2016
Manufacturing companies of the United States
2016 establishments in Massachusetts
American companies established in 2016
Swedish companies established in 2016
Manufacturing companies established in 2016