The caudal pontine reticular nucleus or nucleus reticularis pontis caudalis is a portion of the

reticular formation The reticular formation is a set of interconnected nuclei in the brainstem that spans from the lower end of the medulla oblongata to the upper end of the midbrain. The neurons of the reticular formation make up a complex set of neural networks ...

, composed of gigantocellular neurons. In

rabbit Rabbits are small mammals in the family Leporidae (which also includes the hares), which is in the order Lagomorpha (which also includes pikas). They are familiar throughout the world as a small herbivore, a prey animal, a domesticated ...

s and

cat The cat (''Felis catus''), also referred to as the domestic cat or house cat, is a small domesticated carnivorous mammal. It is the only domesticated species of the family Felidae. Advances in archaeology and genetics have shown that the ...

s it is exclusively giant cells, however in

human Humans (''Homo sapiens'') or modern humans are the most common and widespread species of primate, and the last surviving species of the genus ''Homo''. They are Hominidae, great apes characterized by their Prehistory of nakedness and clothing ...

s there are normally sized cells as well. In rodents, it has been shown to play a role in the acoustic startle response. The caudal pontine reticular nucleus is rostral to the gigantocellular reticular nucleus and is located in the caudal

pons The pons (from Latin , "bridge") is part of the brainstem that in humans and other mammals, lies inferior to the midbrain, superior to the medulla oblongata and anterior to the cerebellum. The pons is also called the pons Varolii ("bridge of ...

. The caudal pontine reticular nucleus has been known to mediate head movement, in concert with the gigantocellular nucleus and the

superior colliculus In neuroanatomy, the superior colliculus () is a structure lying on the tectum, roof of the mammalian midbrain. In non-mammalian vertebrates, the Homology (biology), homologous structure is known as the optic tectum or optic lobe. The adjective f ...

. The neurons in the dorsal half of this nucleus fire rhythmically during

mastication Chewing or mastication is the process by which food is comminution, crushed and ground by the teeth. It is the first step in the process of digestion, allowing a greater surface area for digestive enzymes to break down the foods. During the mast ...

, and in an anesthetized animal it is possible to induce mastication via electrical stimulation of the nucleus reticularis pontis caudalis or adjacent areas of the gigantocellular nucleus.Scott G, Effect of lidocaine and NMDA injections into the medial pontobulbar reticular formation on mastication evoked by cortical stimulation in anaesthetized rabbits. Eur J Neurosci. 2003 May;17(10):2156-62. The caudal pontine reticular nucleus is also thought to play a role in the grinding of teeth during sleep. The region also suppresses muscle tone during REM sleep, activates eye movements, and decreases the sensory input to the cerebral cortex, specifically the primary and sensory somatosensory cortices.

References

External links

NIF Search - Caudal Pontine Reticular Nucleus
via the

Neuroscience Information Framework The Neuroscience Information Framework is a repository of global neuroscience web resources, including experimental, clinical, and translational neuroscience databases, knowledge bases, atlases, and genetic/ genomic resources and provides many aut ...

Pons {{neuroanatomy-stub