The Carlsberg Research Laboratory is a private scientific research center in

Copenhagen Copenhagen ( ) is the capital and most populous city of Denmark, with a population of 1.4 million in the Urban area of Copenhagen, urban area. The city is situated on the islands of Zealand and Amager, separated from Malmö, Sweden, by the ...

Denmark Denmark is a Nordic countries, Nordic country in Northern Europe. It is the metropole and most populous constituent of the Kingdom of Denmark,, . also known as the Danish Realm, a constitutionally unitary state that includes the Autonomous a ...

under the

Carlsberg Foundation Carlsberg Foundation () is a not-for-profit organization that was founded by J. C. Jacobsen in 1876, by allocating some of his shares in the Carlsberg Brewery to fund and operate the Carlsberg Laboratory and the Museum of National History at ...

. It was founded in 1875 by J. C. Jacobsen, the founder of the Carlsberg brewery, with the purpose of advancing

biochemical Biochemistry, or biological chemistry, is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology, ...

knowledge, especially relating to

brewing Brewing is the production of beer by steeping a starch source (commonly cereal grains, the most popular of which is barley) in water and #Fermenting, fermenting the resulting sweet liquid with Yeast#Beer, yeast. It may be done in a brewery ...

. It featured a Department of Chemistry and a Department of Physiology. In 1972, the laboratory was renamed the Carlsberg Research Center and was transferred to the brewery.

Overview

The Carlsberg Laboratory was known for isolating '' Saccharomyces carlsbergensis'', the

species A species () is often defined as the largest group of organisms in which any two individuals of the appropriate sexes or mating types can produce fertile offspring, typically by sexual reproduction. It is the basic unit of Taxonomy (biology), ...

yeast Yeasts are eukaryotic, single-celled microorganisms classified as members of the fungus kingdom (biology), kingdom. The first yeast originated hundreds of millions of years ago, and at least 1,500 species are currently recognized. They are est ...

responsible for

lager Lager (; ) is a Type of beer, style of beer brewed and Brewing#Conditioning, conditioned at low temperature. Lagers can be Pale lager, pale, Amber lager, amber, or Dark lager, dark. Pale lager is the most widely consumed and commercially availab ...

fermentation Fermentation is a type of anaerobic metabolism which harnesses the redox potential of the reactants to make adenosine triphosphate (ATP) and organic end products. Organic molecules, such as glucose or other sugars, are catabolized and reduce ...

, as well as introducing the concept of pH in acid-base

chemistry Chemistry is the scientific study of the properties and behavior of matter. It is a physical science within the natural sciences that studies the chemical elements that make up matter and chemical compound, compounds made of atoms, molecules a ...

. The Danish

chemist A chemist (from Greek ''chēm(ía)'' alchemy; replacing ''chymist'' from Medieval Latin ''alchemist'') is a graduated scientist trained in the study of chemistry, or an officially enrolled student in the field. Chemists study the composition of ...

Søren Peder Lauritz Sørensen introduced the concept of pH, a scale for measuring

acidity An acid is a molecule or ion capable of either donating a proton (i.e. hydrogen cation, H+), known as a Brønsted–Lowry acid, or forming a covalent bond with an electron pair, known as a Lewis acid. The first category of acids are the ...

and

basicity In chemistry, there are three definitions in common use of the word "base": ''Arrhenius bases'', ''Brønsted bases'', and ''Lewis bases''. All definitions agree that bases are substances that react with acids, as originally proposed by Guilla ...

of substances. While working at the Carlsberg Laboratory, he studied the effect of

ion An ion () is an atom or molecule with a net electrical charge. The charge of an electron is considered to be negative by convention and this charge is equal and opposite to the charge of a proton, which is considered to be positive by convent ...

concentration In chemistry, concentration is the abundance of a constituent divided by the total volume of a mixture. Several types of mathematical description can be distinguished: '' mass concentration'', '' molar concentration'', '' number concentration'', ...

on proteins, and understood the concentration of

hydrogen Hydrogen is a chemical element; it has chemical symbol, symbol H and atomic number 1. It is the lightest and abundance of the chemical elements, most abundant chemical element in the universe, constituting about 75% of all baryon, normal matter ...

ions was particularly important. To express the

hydronium ion In chemistry, hydronium (hydroxonium in traditional British English) is the cation , also written as , the type of oxonium ion produced by protonation of water. It is often viewed as the positive ion present when an Arrhenius acid is dissolved in ...

(H₃O⁺) concentration in a

solution Solution may refer to: * Solution (chemistry), a mixture where one substance is dissolved in another * Solution (equation), in mathematics ** Numerical solution, in numerical analysis, approximate solutions within specified error bounds * Solu ...

, he devised a

logarithmic scale A logarithmic scale (or log scale) is a method used to display numerical data that spans a broad range of values, especially when there are significant differences among the magnitudes of the numbers involved. Unlike a linear Scale (measurement) ...

known as the pH scale.

Directors

Footnotes

References

External links

Carlsberg Research Laboratory
{{authority control * Food chemistry organizations Research institutes in Denmark Organizations established in 1875 1875 establishments in Denmark Organizations based in Copenhagen Carlsberg Group buildings and structures Yeast banks

Overview

Directors

See also

Footnotes

References

Further reading

External links