Carlos Bustamante (biophysicist)
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Carlos José Bustamante (born 1951 in
Lima Lima ( ; ), founded in 1535 as the Ciudad de los Reyes (, Spanish for "City of Biblical Magi, Kings"), is the capital and largest city of Peru. It is located in the valleys of the Chillón River, Chillón, Rímac River, Rímac and Lurín Rive ...
,
Peru Peru, officially the Republic of Peru, is a country in western South America. It is bordered in the north by Ecuador and Colombia, in the east by Brazil, in the southeast by Bolivia, in the south by Chile, and in the south and west by the Pac ...
) is a Peruvian-American
scientist A scientist is a person who Scientific method, researches to advance knowledge in an Branches of science, area of the natural sciences. In classical antiquity, there was no real ancient analog of a modern scientist. Instead, philosophers engag ...
. He is a member of the
National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, NGO, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the ...
.


Biography

Carlos Bustamante is a
Howard Hughes Medical Institute The Howard Hughes Medical Institute (HHMI) is an American non-profit medical research organization headquartered in Chevy Chase, Maryland with additional facilities in Ashburn, Virginia. It was founded in 1953 by Howard Hughes, an American busin ...
(HHMI) investigator,
professor Professor (commonly abbreviated as Prof.) is an Academy, academic rank at university, universities and other tertiary education, post-secondary education and research institutions in most countries. Literally, ''professor'' derives from Latin ...
of
molecular A molecule is a group of two or more atoms that are held together by attractive forces known as chemical bonds; depending on context, the term may or may not include ions that satisfy this criterion. In quantum physics, organic chemistry, ...
and cell biology,
physics Physics is the scientific study of matter, its Elementary particle, fundamental constituents, its motion and behavior through space and time, and the related entities of energy and force. "Physical science is that department of knowledge whi ...
, and
chemistry Chemistry is the scientific study of the properties and behavior of matter. It is a physical science within the natural sciences that studies the chemical elements that make up matter and chemical compound, compounds made of atoms, molecules a ...
at the
University of California, Berkeley The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California), is a Public university, public Land-grant university, land-grant research university in Berkeley, California, United States. Founded in 1868 and named after t ...
, and Biophysicist Faculty Scientist at the
Lawrence Berkeley National Laboratory Lawrence Berkeley National Laboratory (LBNL, Berkeley Lab) is a Federally funded research and development centers, federally funded research and development center in the Berkeley Hills, hills of Berkeley, California, United States. Established i ...
.
Bustamante studied medicine at
National University of San Marcos The National University of San Marcos (, UNMSM) is a public university, public research university located in Lima, the capital of Peru. In the Americas, it is the first officially established (Privilege (legal ethics), privilege by Charles V, ...
before discovering his true interest in biochemistry. He received his BSc from
Cayetano Heredia University Cayetano Heredia University (, UPCH; or simply ''Cayetano Heredia'') is a private nonprofit university located in Lima, Peru. It was named in honor of Cayetano Heredia, one of the eminent Peruvian physicians of the 19th century. The universit ...
in Lima, his MSc in
biochemistry Biochemistry, or biological chemistry, is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology, a ...
from
National University of San Marcos The National University of San Marcos (, UNMSM) is a public university, public research university located in Lima, the capital of Peru. In the Americas, it is the first officially established (Privilege (legal ethics), privilege by Charles V, ...
in Lima, and his PhD in
biophysics Biophysics is an interdisciplinary science that applies approaches and methods traditionally used in physics to study biological phenomena. Biophysics covers all scales of biological organization, from molecular to organismic and populations ...
from
UC Berkeley The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California), is a public land-grant research university in Berkeley, California, United States. Founded in 1868 and named after the Anglo-Irish philosopher George Berkele ...
, where he studied with Ignacio Tinoco, Jr. As a postdoctoral fellow at the
Lawrence Berkeley National Laboratory Lawrence Berkeley National Laboratory (LBNL, Berkeley Lab) is a Federally funded research and development centers, federally funded research and development center in the Berkeley Hills, hills of Berkeley, California, United States. Established i ...
, Bustamante studied with Marcos Maestre. Before moving to Berkeley, he was an
HHMI The Howard Hughes Medical Institute (HHMI) is an American non-profit medical research organization headquartered in Chevy Chase, Maryland with additional facilities in Ashburn, Virginia. It was founded in 1953 by Howard Hughes, an American busin ...
investigator at the
University of Oregon The University of Oregon (UO, U of O or Oregon) is a Public university, public research university in Eugene, Oregon, United States. Founded in 1876, the university is organized into nine colleges and schools and offers 420 undergraduate and gra ...
.


Research focus

Carlos Bustamante uses novel methods of single-molecule visualization, such as scanning force microscopy, to study the structure and function of
nucleoprotein Nucleoproteins are proteins conjugated with nucleic acids (either DNA or RNA). Typical nucleoproteins include ribosomes, nucleosomes and viral nucleocapsid proteins. Structures Nucleoproteins tend to be positively charged, facilitating inte ...
assemblies. His laboratory is developing methods of single-molecule manipulation, such as
optical tweezers Optical tweezers (originally called single-beam gradient force trap) are scientific instruments that use a highly focused laser beam to hold and move microscopic and sub-microscopic objects like atoms, nanoparticles and droplets, in a manner simil ...
, to characterize the elasticity of
DNA Deoxyribonucleic acid (; DNA) is a polymer composed of two polynucleotide chains that coil around each other to form a double helix. The polymer carries genetic instructions for the development, functioning, growth and reproduction of al ...
, to induce the mechanical unfolding of individual
protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metab ...
molecules A molecule is a group of two or more atoms that are held together by attractive forces known as chemical bonds; depending on context, the term may or may not include ions that satisfy this criterion. In quantum physics, organic chemistry ...
, and to investigate the machine-like behavior of molecular motors.


Positions

* Research assistant,
UC Berkeley The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California), is a public land-grant research university in Berkeley, California, United States. Founded in 1868 and named after the Anglo-Irish philosopher George Berkele ...
(1976–1981) * Postdoctoral fellow, Lawrence Berkeley Laboratory,
UC Berkeley The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California), is a public land-grant research university in Berkeley, California, United States. Founded in 1868 and named after the Anglo-Irish philosopher George Berkele ...
(1981–1982) * Assistant professor, department of chemistry,
University of New Mexico The University of New Mexico (UNM; ) is a public research university in Albuquerque, New Mexico, United States. Founded in 1889 by the New Mexico Territorial Legislature, it is the state's second oldest university, a flagship university in th ...
(1982–1986) * Associate professor, department of chemistry,
University of New Mexico The University of New Mexico (UNM; ) is a public research university in Albuquerque, New Mexico, United States. Founded in 1889 by the New Mexico Territorial Legislature, it is the state's second oldest university, a flagship university in th ...
(1986–1989) * Professor of chemistry, department of chemistry,
University of New Mexico The University of New Mexico (UNM; ) is a public research university in Albuquerque, New Mexico, United States. Founded in 1889 by the New Mexico Territorial Legislature, it is the state's second oldest university, a flagship university in th ...
(1989–1990) * Professor of chemistry and member of the Institute of Molecular Biology,
University of Oregon The University of Oregon (UO, U of O or Oregon) is a Public university, public research university in Eugene, Oregon, United States. Founded in 1876, the university is organized into nine colleges and schools and offers 420 undergraduate and gra ...
(1991–1998) * Professor in molecular and cell biology, chemistry, and physics,
UC Berkeley The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California), is a public land-grant research university in Berkeley, California, United States. Founded in 1868 and named after the Anglo-Irish philosopher George Berkele ...
(1998–present) * Honorary professor,
National University of San Marcos The National University of San Marcos (, UNMSM) is a public university, public research university located in Lima, the capital of Peru. In the Americas, it is the first officially established (Privilege (legal ethics), privilege by Charles V, ...
, Lima, Peru


Fellowships and awards

* Kellogg Foundation scholarship during the Master in Biochemistry (1973–1975) *
Fulbright Commission The Fulbright Program, including the Fulbright–Hays Program, is one of several United States cultural exchange programs with the goal of improving intercultural relations, cultural diplomacy, and intercultural competence between the people o ...
and
Institute of International Education The Institute of International Education (IIE) is an American 501(c) non-profit organization that focuses on international student exchange and aid, foreign affairs, and international peace and security. IIE creates programs of study and training ...
Fellow (1975–1976) *
Abraham Rosenberg Abraham (originally Abram) is the common Hebrew patriarch of the Abrahamic religions, including Judaism, Christianity, and Islam. In Judaism, he is the founding father who began the covenantal relationship between the Jewish people and God; ...
scholarship, UC Berkeley (1975–1976) *
Searle Scholar The Searle Scholars Program is a career development award made annually to support 15 young faculty in biomedical research and chemistry at US universities and research centers. The goal of the award is to support to exceptional young scientists wh ...
(1984) *
Alfred P. Sloan Foundation The Alfred P. Sloan Foundation is an American philanthropic nonprofit organization. It was established in 1934 by Alfred P. Sloan Jr., president and chief executive officer of General Motors. The Sloan Foundation makes grants to support origina ...
Fellow (1985) * Presidential Lecturer in Chemistry, University of New Mexico (1986) * State of New Mexico Eminent Scholar (1989) *
Howard Hughes Medical Institute The Howard Hughes Medical Institute (HHMI) is an American non-profit medical research organization headquartered in Chevy Chase, Maryland with additional facilities in Ashburn, Virginia. It was founded in 1953 by Howard Hughes, an American busin ...
Investigator (1994–1998, 2000–present) * Elected Fellow of the
American Physical Society The American Physical Society (APS) is a not-for-profit membership organization of professionals in physics and related disciplines, comprising nearly fifty divisions, sections, and other units. Its mission is the advancement and diffusion of ...
(1995), Citation: ''For pioneering the application of optical methods and scanning probes in measurements of the properties of single DNA molecules.'' * Member of the science advisory board of the Searle Scholars Program (1997–2000) * Member of the board of trustees at the
IMDEA IMDEA () is a project founded by the Madrid Regional Government, included in the ''IV Regional Plan of Scientific Research and Technological Innovation 2005-2008 (PRICIT)'', for the purpose of setting up advanced research centers and higher educat ...
Nanoscience Institute * Elected member, National Academy of Sciences,
Biophysics Biophysics is an interdisciplinary science that applies approaches and methods traditionally used in physics to study biological phenomena. Biophysics covers all scales of biological organization, from molecular to organismic and populations ...
2002 *
Max Delbrück Max Ludwig Henning Delbrück (; September 4, 1906 – March 9, 1981) was a German–American biophysicist who participated in launching the molecular biology research program in the late 1930s. He stimulated physical science, physical scientist ...
Prize in Biological Physics (2002) * Hans Neurath Award of the Protein Society (2004) * In 2005 he received the
Richtmyer Memorial Award The Richtmyer Memorial Award is an award for physics education, named for physicist Floyd K. Richtmyer and given annually by the American Association of Physics Teachers. Its recipients include over 15 Nobel Prize winners. Establishment and award ...
given annually by the
American Association of Physics Teachers The American Association of Physics Teachers (AAPT) was founded in 1930 for the purpose of "dissemination of knowledge of physics, particularly by way of teaching." There are more than 10,000 members in over 30 countries. AAPT publications includ ...
. *
Alexander Hollaender Award in Biophysics Alexander () is a male name of Greek origin. The most prominent bearer of the name is Alexander the Great, the king of the Ancient Greek kingdom of Macedonia who created one of the largest empires in ancient history. Variants listed here are A ...
(2004) * Doctor Honoris Causa of
National University of San Marcos The National University of San Marcos (, UNMSM) is a public university, public research university located in Lima, the capital of Peru. In the Americas, it is the first officially established (Privilege (legal ethics), privilege by Charles V, ...
, Lima, Peru * Vilcek Prize in Biomedical Science (2012) * Raymond and Beverly Sackler International Prize in the Physical Sciences (2012)


References


External links

* {{DEFAULTSORT:Bustamante, Carlos 1951 births Members of the United States National Academy of Sciences Living people Scientists from Lima Peruvian chemists American chemists Peruvian emigrants to the United States National University of San Marcos alumni University of California, Berkeley alumni Howard Hughes Medical Investigators University of Oregon faculty Fellows of the American Physical Society UC Berkeley College of Chemistry faculty Hispanic and Latino American scientists Hispanic and Latino American physicists Searle Scholars Program recipients