Cannabigerolic acid

Cannabigerolic acid (CBGA) is the acidic form of cannabigerol (CBG). It is a dihydroxybenzoic acid and

olivetolic acid Olivetolic acid is an organic compound that is an intermediate in the biosynthetic pathway of the cannabinoids in ''Cannabis sativa ''Cannabis sativa'' is an annual herbaceous flowering plant indigenous to Eastern Asia, but now of cosmopoli ...

in which the hydrogen at position 3 is substituted by a geranyl group. It is a biosynthetic precursor to

Delta-9-tetrahydrocannabinol Tetrahydrocannabinol (THC) is the principal psychoactive constituent of cannabis and one of at least 113 total cannabinoids identified on the plant. Although the chemical formula for THC (C21H30O2) describes multiple isomers, the term ''THC'' ...

, which is the principal psychoactive constituent of the '' Cannabis'' plant. It is also a diterpenoid, a polyketide, a member of resorcinols and a phytocannabinoid. It derives from an olivetolic acid. It is a conjugate acid of a cannabigerolate. In the ''Cannabis'' plant, olivetolic acid and geranyl diphosphate are synthesized into CBGA. CBGA is converted in the plant by CBCA synthase,

CBDA synthase Cannabidiolic acid synthase (, ''CBDA synthase'') is an enzyme with systematic name ''cannabigerolate:oxygen oxidoreductase (cyclizing, cannabidiolate-forming)''. It is an oxidoreductase found in ''Cannabis sativa'' that catalyses the formation ...

and

THCA synthase Tetrahydrocannabinolic acid (THCA) synthase (full name ''Δ1-tetrahydrocannabinolic acid synthase'') is an enzyme responsible for catalyzing the formation of THCA from cannabigerolic acid (CBGA). THCA is the direct precursor of tetrahydrocann ...

into CBCA,

CBDA Cannabidiolic acid synthase (, ''CBDA synthase'') is an enzyme with List of enzymes, systematic name ''cannabigerolate:oxygen oxidoreductase (cyclizing, cannabidiolate-forming)''. It is an oxidoreductase found in ''Cannabis sa