COG3860 RNA Motif
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The COG3860 RNA motif is a conserved
RNA Ribonucleic acid (RNA) is a polymeric molecule that is essential for most biological functions, either by performing the function itself (non-coding RNA) or by forming a template for the production of proteins (messenger RNA). RNA and deoxyrib ...
structure that was discovered by bioinformatics. COG3860 motifs are found in
Alphaproteobacteria ''Alphaproteobacteria'' or ''α-proteobacteria'', also called ''α-Purple bacteria'' in earlier literature, is a class of bacteria in the phylum '' Pseudomonadota'' (formerly "Proteobacteria"). The '' Magnetococcales'' and '' Mariprofundales'' ar ...
,
Betaproteobacteria ''Betaproteobacteria'' are a class of Gram-negative bacteria, and one of the six classes of the phylum '' Pseudomonadota'' (synonym Proteobacteria). Metabolism The ''Betaproteobacteria'' comprise over 75 genera and 400 species. Together, they ...
, and
Thermodesulfobacteriota The Thermodesulfobacteriota, or Desulfobacterota, are a phylum of anaerobic Gram-negative bacteria. Many representatives are sulfate-reducing bacteria, others can grow by disproportionation of various sulphur species, reduction or iron, or even u ...
. Energetically stable
tetraloop Tetraloops are a type of four-base hairpin loop motifs in RNA secondary structure that cap many double helices. There are many variants of the tetraloop. The published ones include ANYA, CUYG, GNRA, UNAC and UNCG. Three types of tetraloops ar ...
s often occur in this motif. COG3860 motif RNAs likely function as ''cis''-regulatory elements, in view of their positions upstream of protein-coding
gene In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protei ...
s. Unfortunately the functions of the putatively regulated genes are not sufficiently well known to be able to hypothesize a biological function for COG3860 RNAs.


References

{{reflist Non-coding RNA