CCR4-NOT transcription complex subunit 8 is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respon ...
that in humans is encoded by the ''CNOT8''
gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b ...
.
It is a subunit of the
CCR4-Not deadenylase complex.
Interactions
CNOT8 has been shown to
interact with
BTG2,
BTG1
Protein BTG1 is a protein that in humans is encoded by the ''BTG1'' gene.
Function
The BTG1 gene locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia. It is a mem ...
,
CNOT1 and CNOT3.[
]
References
Further reading
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External links
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