Borealin is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metab ...
that in humans is encoded by the ''CDCA8''
gene
In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protei ...
.
Function
CDCA8 is a component of a chromosomal passenger complex required for stability of the bipolar mitotic spindle.
Interactions
CDCA8 has been shown to
interact with
INCENP
Inner centromere protein is a protein that in humans is encoded by the ''INCENP'' gene. It is a regulatory protein in the chromosome passenger Protein complex, complex (CPC) . It is involved in regulation of the catalytic proteins Aurora kinase ...
,
Survivin
Survivin, also called baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5, is a protein that, in humans, is encoded by the ''BIRC5'' gene.
Survivin is a member of the inhibitor of apoptosis (IAP) family. The survivin protein functi ...
and
Aurora B kinase.
References
Further reading
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External links
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