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Johanna Budwig (1908 – 2003) was a German
biochemist Biochemists are scientists who are trained in biochemistry. They study chemical processes and chemical transformations in living organisms. Biochemists study DNA, proteins and Cell (biology), cell parts. The word "biochemist" is a portmanteau of ...
,
alternative cancer treatment Alternative cancer treatment describes any cancer treatment or practice that is not part of the conventional standard of cancer care. These include special diets and exercises, chemicals, herbs, devices, and manual procedures. Most alternative ...
advocate and writer.Kerckhof, Annette. (2020). ''Budwig, Johanna (1908–2003)''. In ''Wichtige Frauen in der Naturheilkunde''. Springer. pp. 65-69. Budwig was a
pharmacist A pharmacist, also known as a chemist in English in the Commonwealth of Nations, Commonwealth English, is a healthcare professional who is knowledgeable about preparation, mechanism of action, clinical usage and legislation of medications in ...
and held
doctorate A doctorate (from Latin ''doctor'', meaning "teacher") or doctoral degree is a postgraduate academic degree awarded by universities and some other educational institutions, derived from the ancient formalism '' licentia docendi'' ("licence to teach ...
degrees in
physics Physics is the scientific study of matter, its Elementary particle, fundamental constituents, its motion and behavior through space and time, and the related entities of energy and force. "Physical science is that department of knowledge whi ...
and
chemistry Chemistry is the scientific study of the properties and behavior of matter. It is a physical science within the natural sciences that studies the chemical elements that make up matter and chemical compound, compounds made of atoms, molecules a ...
. Based on her research on
fatty acid In chemistry, in particular in biochemistry, a fatty acid is a carboxylic acid with an aliphatic chain, which is either saturated and unsaturated compounds#Organic chemistry, saturated or unsaturated. Most naturally occurring fatty acids have an ...
s she developed a
lacto-vegetarian A lacto-vegetarian (sometimes referred to as a lactarian; from the Latin root lact-, ''milk'') diet abstains from the consumption of meat as well as Egg as food, eggs, while still consuming dairy products such as milk, cheese (without animal renn ...
diet that she believed was useful in the
treatment of cancer Cancer treatments are a wide range of treatments available for the many different types of cancer, with each cancer type needing its own specific treatment. Treatments can include surgery, chemotherapy, radiation therapy, hormonal therapy (oncolo ...
. There is no clinical evidence that the Budwig diet is effective, and it may cause adverse effects.


Biography

Budwig was born in
Essen Essen () is the central and, after Dortmund, second-largest city of the Ruhr, the largest urban area in Germany. Its population of makes it the fourth-largest city of North Rhine-Westphalia after Cologne, Düsseldorf and Dortmund, as well as ...
and at the age of 16 joined the Kaiserswerth Deaconess Institute. She studied pharmacy in
Königsberg Königsberg (; ; ; ; ; ; , ) is the historic Germany, German and Prussian name of the city now called Kaliningrad, Russia. The city was founded in 1255 on the site of the small Old Prussians, Old Prussian settlement ''Twangste'' by the Teuton ...
and
Münster Münster (; ) is an independent city#Germany, independent city (''Kreisfreie Stadt'') in North Rhine-Westphalia, Germany. It is in the northern part of the state and is considered to be the cultural centre of the Westphalia region. It is also a ...
where she met her mentor Prof. Hans Kaufmann the founder of the German Institute for Fat Research. She worked under Kaufmann as a research assistant and completed her doctorate in 1939. While working as a researcher at the German Federal Health Office she noted many cancer drugs being evaluated in the 1950s contained sulphydryl groups. Budwig believed sulphydryl compounds were important to cellular
metabolism Metabolism (, from ''metabolē'', "change") is the set of life-sustaining chemical reactions in organisms. The three main functions of metabolism are: the conversion of the energy in food to energy available to run cellular processes; the co ...
and
cellular respiration Cellular respiration is the process of oxidizing biological fuels using an inorganic electron acceptor, such as oxygen, to drive production of adenosine triphosphate (ATP), which stores chemical energy in a biologically accessible form. Cell ...
. Budwig researched the theory that a low oxygen environment would develop in the absence of sulphydryl groups and/or fatty acid partners that would encourage the proliferation of cancerous cells. With Kaufmann she developed
paper chromatography Paper chromatography is an analytical method used to separate colored chemicals or substances. It can also be used for colorless chemicals that can be located by a stain or other visualisation method after separation. It is now primarily used as ...
techniques to identify and quantify fatty acids. Budwig used these techniques to compare the fatty acid profiles of sick and healthy individuals. In 1950, Budwig and Kaufmann presented their findings at the International Fat Congress on "New approaches in fat analysis". She argued that highly heated and chemically modified fats found primarily in
margarine Margarine (, also , ) is a Spread (food), spread used for flavoring, baking, and cooking. It is most often used as a substitute for butter. Although originally made from animal fats, most margarine consumed today is made from vegetable oil. The ...
were dangerous to human health. In 1951, Budwig was chief expert for pharmaceuticals and fats in the Federal Institute for Fat Research but resigned over controversy due to her critical statements about trans fatty acids. Budwig came to the conclusion that industrial processed fats were a strain on health and caused cardiovascular disease and cancer, whilst polyunsaturated fatty acids were protective. She argued that linseed oil which contains alpha-Linolenic acid, an essential omega-3 fatty acid and sulphur proteins in the form of low-fat
quark A quark () is a type of elementary particle and a fundamental constituent of matter. Quarks combine to form composite particles called hadrons, the most stable of which are protons and neutrons, the components of atomic nucleus, atomic nuclei ...
or cottage cheese are a great importance in the diet. She became known for her "Budwig Creme", for which linseed oil, milk and low-fat quark are stirred together until no oil is left. Budwig died in
Freudenstadt Freudenstadt (, Swabian: ''Fraidestadt'') is a town in Baden-Württemberg in southern Germany. It is the capital of the district Freudenstadt. The closest population centres are Offenburg to the west (approx. 36 km away) and Tübingen to ...
in 2003 at the age of 94 as a result of a
femoral neck fracture A hip fracture is a bone fracture, break that occurs in the upper part of the femur (thigh bone), at the femoral neck or (rarely) the femoral head. Symptoms may include hip pain, pain around the hip, particularly with movement, and shortenin ...
.


The Budwig Diet

In 1952 she described a diet which she claimed had anti-cancer effects. She called it the “Budwig protocol”. The focus of this diet is on modifying the intake of dietary fats. It is a lacto-vegetarian diet rich in
flaxseed oil Linseed oil, also known as flaxseed oil or flax oil (in its edible form), is a colorless to yellowish oil obtained from the dried, ripened seeds of the flax plant (''Linum usitatissimum''). The oil is obtained by pressing, sometimes followed by ...
and other cold-pressed vegetable oils, mixed with cottage cheese and meals high in fruits, vegetables with sauerkraut, freshly squeezed juices, nuts and seeds. The diet avoids animal fats, butter, margarine, meat, seafood and sugar. She recommended the consumption of garlic, leeks or onions as these plants contain proteins with sulphur content. Her dietary ideas inspired the research of Catherine Kousmine.Käsmayr, Anneli. (2017). ''Culinary Turn Aesthetic Practice of Cookery''. Transcript Verlag. p. 165. There is no clinical evidence supporting the claims of the Budwig diet against cancer.
Adverse effects An adverse effect is an undesired harmful effect resulting from a medication or other intervention, such as surgery. An adverse effect may be termed a "side effect", when judged to be secondary to a main or therapeutic effect. The term complic ...
of the diet have included
malnutrition Malnutrition occurs when an organism gets too few or too many nutrients, resulting in health problems. Specifically, it is a deficiency, excess, or imbalance of energy, protein and other nutrients which adversely affects the body's tissues a ...
,
stomach ache Abdominal pain, also known as a stomach ache, is a symptom associated with both non-serious and serious medical issues. Since the abdomen contains most of the body's vital organs, it can be an indicator of a wide variety of diseases. Given th ...
,
flatulence Flatulence is the expulsion of gas from the Gastrointestinal tract, intestines via the anus, commonly referred to as farting. "Flatus" is the medical word for gas generated in the stomach or bowels. A proportion of intestinal gas may be swal ...
, and
allergic reactions Allergies, also known as allergic diseases, are various conditions caused by hypersensitivity of the immune system to typically harmless substances in the environment. These diseases include hay fever, food allergies, atopic dermatitis, alle ...
. People with cancer who delay or forgo effective treatments as a result of using diets such as the Budwig Diet might suffer
relapse In internal medicine, relapse or recidivism is a recurrence of a past (typically medical) condition. For example, multiple sclerosis and malaria often exhibit peaks of activity and sometimes very long periods of dormancy, followed by relapse or r ...
, experience unnecessary disease progression, and experience continuing cancer-related symptoms.


Selected publications

*''Flax Oil as a True Aid against Arthritis, Heart Infarction and Cancer'' (1994) *''The Oil Protein Diet Cookbook'' (2006)


See also

*
List of unproven and disproven cancer treatments This is a non-exhaustive list of alternative cancer treatments, alternative treatments that have been promoted to treat or prevent cancer in humans but which lack scientific and medical evidence of effectiveness. In many cases, there is scientif ...
*
Quackery Quackery, often synonymous with health fraud, is the promotion of fraudulent or Ignorance, ignorant medicine, medical practices. A quack is a "fraudulent or ignorant pretender to medical skill" or "a person who pretends, professionally or public ...


References


External links


Works by Budwig in the Deutsche Nationalbibliothek
{{DEFAULTSORT:Budwig, Johanna 1908 births 2003 deaths 20th-century German inventors Alternative cancer treatment advocates Cancer researchers German biochemists German pharmacists German vegetarianism activists Pseudoscientific diet advocates German women biochemists Vegetarian cookbook writers 20th-century women inventors Writers from Essen