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Biopsychosocial models (BPSM) are a class of trans-disciplinary models which look at the interconnection between
biology Biology is the scientific study of life and living organisms. It is a broad natural science that encompasses a wide range of fields and unifying principles that explain the structure, function, growth, History of life, origin, evolution, and ...
,
psychology Psychology is the scientific study of mind and behavior. Its subject matter includes the behavior of humans and nonhumans, both consciousness, conscious and Unconscious mind, unconscious phenomena, and mental processes such as thoughts, feel ...
, and socio- environmental factors. These models specifically examine how these aspects play a role in a range of topics but mainly
psychiatry Psychiatry is the medical specialty devoted to the diagnosis, treatment, and prevention of deleterious mental disorder, mental conditions. These include matters related to cognition, perceptions, Mood (psychology), mood, emotion, and behavior. ...
, health and human development. The term is generally used to describe a model advocated by George L. Engel in 1977. The model builds upon the idea that "illness and health are the result of an interaction between biological, psychological, and social factors". The idea behind the model was to express mental distress as a triggered response of a disease that a person is genetically vulnerable to when stressful life events occur. In that sense, it is also known as vulnerability-stress model. It then became referred to as a generalized model that interpreted similar aspects, and became an alternative to the biomedical and/or psychological dominance of many health care systems. As of 2017 the BPSM had become generally accepted. It grew in interest for researchers in healthcare and active medical professionals in the decade to 2020.


Current status

A 2024 review proposed use of the BPSM because the biomedical model did not fit the social and psychological aspects of health problems. A 2023 review said that in the previous decades substantial evidence had arisen supporting BPSM, although the theory of it remained unclear. A 2021 review found a substantial gap between healthcare professionals knowledge of the BPSM and their adoption of it in clinical practice. A 2018 review found that BPSM in primary care could lead to improved clinical outcomes, through creating awareness of factors impacting health and enhancing self-management of patients' illnesses. A 2007 review said that the biopsychosocial model was widely accepted as the most
heuristic A heuristic or heuristic technique (''problem solving'', '' mental shortcut'', ''rule of thumb'') is any approach to problem solving that employs a pragmatic method that is not fully optimized, perfected, or rationalized, but is nevertheless ...
approach to understanding and treating chronic pain. A 2004 review said the BPSM was widely used as both a philosophy of clinical care and a practical clinical guide useful for broadening the scope of a clinician's gaze. It proposed the model had evolved into a biopsychosocial and relationship-centered framework for physicians. It proposed three clarifications to the model, and identified seven established principles. * Self-awareness. * Active cultivation of trust. * An emotional style characterized by empathic curiosity. * Self-calibration as a way to reduce bias. * Educating the emotions to assist with diagnosis and forming therapeutic relationships. * Using informed intuition. * Communicating clinical evidence to foster dialogue, not just the mechanical application of protocol.


Institutional recognition

In the decade to 2015 there was a rising interest among healthcare researchers and practicing medical professionals in the biopsychosocial model. However, despite the rising interest, medical schools had limited use of the model in their curriculums relative to the increasing literature about the model.


Biopsychosocial model vs. Biomedical model

The biopsychosocial and biomedical models offer distinct perspectives on understanding and addressing health and illness.


Biomedical model

The biomedical model, which was historically prevalent, takes a reductionist approach by focusing on biological factors and treating diseases through medical interventions. It sees diseases as isolated physical abnormalities. While this approach was once deemed sufficient, research within psychology and the social sciences cast doubt on its effectiveness.


Biopsychosocial model

The biopsychosocial model adopts a holistic viewpoint, acknowledging the complex interplay of biological, psychological, and social factors in shaping health and illness. It sees diseases as outcomes of dynamic interactions among various dimensions. The model emphasizes the interconnectedness of these dimensions, recognizing their mutual influence on an individual's health. The BPSM has been extended to consider additional holistic elements influencing the perceived necessity for healthcare and the focus on health-related matters: Information, Beliefs, and Conduct. Based on the model's dependence on perception, it has been considered imperative to actively engage the individuals or communities whose requirements are being addressed, regardless of whether the focus is on their health, education, employment, housing, or any other needs. A key term in the biopsychosocial model is "syndemic" which refers to a set of health problem factors that interact synergistically with each other ranging from socioeconomic status to genetics. Treatment under the biopsychosocial model is comprehensive, involving medical, psychological, and social interventions to address overall well-being.


In relation to patient populations

Health inequities, often rooted in social determinants of health, highlight the disparities in health outcomes experienced by different populations. The BPSM provides a framework for comprehending how health disparities arise and persist, which makes it a model of interest in targeting health inequities. Some patients that fall under the biopsychosocial model may not fall under the biomedical model, as the biopsychosocial model considers factors that may not physiologically manifest in a person. These patients include those affected by health inequities and those at risk of infirmity.


In relation to prevention

Preventative medicine considers preventative measures to stop patients from obtaining infirmity in the first place. By combatting preventable chronic diseases which make up a majority of deaths in patients of the US, the BPSM has been considered a potential tool to improve patient outcomes. SAMHSA has promoted BPSM approaches in preventing opioid use.


In relation to gender

Within the framework of the biopsychosocial model, gender is regarded by some as a complex and nuanced construct, shaped by the intricate interplay of social, psychological, and biological factors. This perspective, as echoed by the Gender Spectrum Organization, defines gender as the multifaceted interrelationship between three key dimensions: body, identity, and social gender. In essence, this characterization aligns with the fundamental principles of the biopsychosocial model, emphasizing the need to consider not only biological determinants but also the profound influences of psychological and social contexts on the formation of gender. According to the insights of Alex Iantaffi and Meg-John Barker, the biopsychosocial model provides a comprehensive framework to understand the complexities of gender. They illustrate that biological, psychological, and social factors are not isolated entities but rather intricately intertwined elements that continually interact and shape one another. In this dynamic process, a person's gender identity emerges as the result of a complex interplay between their biological characteristics, psychological experiences, and social interactions. This holistic perspective is in harmony with the biopsychosocial model's approach, which acknowledges the inseparable connection between these various dimensions in influencing an individual's overall well-being. In essence, within the biopsychosocial paradigm, gender is not merely a product of biological determinants; rather, it is a dynamic and interconnected aspect of human identity. This perspective urges a more nuanced understanding, encouraging researchers and medical professionals to consider the intricate interplay of social, psychological, and biological factors when exploring and addressing the complexities of gender.


Models, theories and theorists

The following models or theories are regarded as biopsychosocial; *Engel's model, as above. *The Dynamic-Maturational Model of Attachment and Adaptation (DMM) describes how attachment relationships, and other factors, effect human development, information processing and functioning. Crittenden considered this to be a biopsychosocial model. * Kozlowska's Functional Somatic Symptoms approach sees attachment relationships and other factors as causes of somatic problems. Siegel's Interpersonal Neurobiology (IPNB) model is similar to Kozlowska's approach, but sees the individual brain and mind, and interpersonal relationships, as part of one reality, rather than separate elements. *Some trauma informed care models are biopsychosocial models. *In 2012 Lumley and colleagues used a non-Engel model to conduct a biopsychosocial assessment of the relationship between pain and emotion. *In 1986 Zucker and Gomberg used a non-Engel biopsychosocial perspective to assess the etiology of alcoholism.


Potential applications


Understanding of medical effects

When Engel first proposed the biopsychosocial model it was for the purpose of better understanding health and illness. While this application still holds true the model is relevant to topics such as health, medicine, and development. Firstly, as proposed by Engel, it helps physicians better understand their whole patient. Considering not only physiological and medical aspects but also psychological and sociological well-being. Furthermore, this model is closely tied to health psychology. Health psychology examines the reciprocal influences of biology, psychology, behavioral, and social factors on health and illness.


Primary care

BPSM can improve primary care clinical outcomes, through creating awareness on the interactions among biological, psychological, sociocultural, and spiritual factors, and enhancing self-management of patients' illnesses.


Chronic and ill-defined conditions

BPSM is useful to address chronic diseases and ill-defined illnesses to which patients mount unique responses.


Pain

BPSM can be applied in relation to pain. Several factors outside an individual's health may affect their perception of pain. For example, a 2019 study linked genetic and biopsychosocial factors to increased post-operative shoulder pain. Future studies are needed to model and further explore the relationship between biopsychosocial factors and pain.


Mental health and psychology

Correlation has been found between adverse childhood experiences and subsequent health and well-being outcomes. A BPSM appraisal can be used in diagnosis of depression and
anxiety Anxiety is an emotion characterised by an unpleasant state of inner wikt:turmoil, turmoil and includes feelings of dread over Anticipation, anticipated events. Anxiety is different from fear in that fear is defined as the emotional response ...
. One advantage of applying the biopsychosocial model to
developmental psychology Developmental psychology is the scientific study of how and why humans grow, change, and adapt across the course of their lives. Originally concerned with infants and children, the field has expanded to include adolescence, adult development ...
is that it allows for an intersection within the nature versus nurture debate. This model provides developmental psychologists a theoretical basis for the interplay of both hereditary and psychosocial factors on an individual's development.


Care

The BPSM approach has been used as a framework for or component of care.


Biopsychosocial research

Wickrama and colleagues have conducted several biopsychosocial-based studies examining marital dynamics. In a longitudinal study of women divorced midlife they found that divorce contributed to an adverse biopsychosocial process for the women. In another study of enduring marriages, they looked to see if hostile marital interactions in the early middle years could wear down couples regulator systems through greater psychological distress, more health-risk behaviors, and a higher body mass index (BMI). Their findings confirmed negative outcomes and increased vulnerability to later physical health problems for both husbands and wives. Kovacs and colleagues meta-study examined the biopsychosocial experiences of adults with congenital heart disease. Zhang and colleagues used a biopsychosocial approach to examine parents own physiological response when facing children's negative emotions, and how it related to parents' ability to engage in sensitive and supportive behaviors. They found parents' physiological regulatory functioning was an important factor in shaping parenting behaviors directed toward children's emotions. A biopsychosocial approach was used to assess race and ethnic differences in aging and to develop the Michigan Cognitive Aging Project. Banerjee and colleagues used a biopsychosocial narrative to describe the dual pandemic of suicide and COVID-19. Despite its theoretical robustness and growing empirical support, the implementation of this model in clinical practice remains inconsistent, hindered by systemic, professional, and cultural barriers. Artificial intelligence-driven tools are also being explored to integrate biopsychosocial data into clinical decision-making, enabling personalized treatment plans that reflect the complexity of each patient's condition.


Criticisms

There have been a number of criticisms of Engel's biopsychosocial model. Benning summarized the arguments against the model including that it *lacked philosophical coherence, *was insensitive to patients' subjective experience, *was unfaithful to the
general systems theory Systems theory is the transdisciplinary study of systems, i.e. cohesive groups of interrelated, interdependent components that can be natural or artificial. Every system has causal boundaries, is influenced by its context, defined by its struc ...
that Engel claimed it be rooted in, *engendered an undisciplined
eclecticism Eclecticism is a conceptual approach that does not hold rigidly to a single paradigm or set of assumptions, but instead draws upon multiple theories, styles, or ideas to gain complementary insights into a subject, or applies different theories i ...
that provided no safeguards against either the dominance or the under-representation of any one of the three domains of bio, psycho, or social. Psychiatrist Hamid Tavakoli argued that Engel's biopsychosocial model should be avoided because it *unintentionally promoted an artificial distinction between biology and psychology, and *caused confusion in psychiatric assessments and training programs, *ultimately it has not helped the cause of trying to de-stigmatize mental health. The perspectives model does not make that arbitrary distinction. A number of these criticisms have been addressed. For example, the biopsychosocial pathways model describes how it is possible to conceptually separate, define, and measure biological, psychological, and social factors, and thereby seek detailed interrelationships among these factors. As of 2017 whilst Engel's call to arms for a biopsychosocial model had been taken up in several healthcare fields and developed in related models, it had not been adopted in acute medical and surgical domains.


History

The BPSM was proposed in the late 1800s. The idea that there are several factors that may contribute to one's mental suffering is nothing new. Psychologist
Urie Bronfenbrenner Urie Bronfenbrenner (April 29, 1917, Moscow – September 25, 2005) was a Russian-born American psychologist best known for using a contextual framework to better understand human development. This framework, broadly referred to as 'ecological sys ...
popularized the belief that social factors play a role in developing illnesses and behaviors. Engel later used Bronfenbrenner's research as a column of his biopsychosocial model and framed this model to display health at the center of social, psychological, and biological aspects. Adolf Meyer's psychobiology model is considered the forerunner to the biopsychosocial model by many. Meyer emphasised understanding mental illness in the context of a patient's personal history over diagnostic categories. Meyer laid down the groundwork for understanding the interplay of psychology and biology but tended to view these as separate entities that interacted. Engel's model represents a broader and more integrated approach that considers biological, psychological, and social factors as interconnected elements. The WHO definition of health adopted in 1948 implied a broad socio-medical perspective. Roy Grinker actually coined the term 'biopsychosocial' long before Engel (1954 vs 1977). However Grinker was seeking to highlight biological aspects of mental health, rather than Engel's emphasis on psychosocial aspects of general health. Engel broadened medical thinking by re-proposing a separation of body and mind. The idea of
mind–body dualism In the philosophy of mind, mind–body dualism denotes either that mental phenomena are non-physical, Hart, W. D. 1996. "Dualism." pp. 265–267 in ''A Companion to the Philosophy of Mind'', edited by S. Guttenplan. Oxford: Blackwell. or t ...
goes back at least to
René Descartes René Descartes ( , ; ; 31 March 1596 – 11 February 1650) was a French philosopher, scientist, and mathematician, widely considered a seminal figure in the emergence of modern philosophy and Modern science, science. Mathematics was paramou ...
, but was forgotten during the biomedical approach. Engel emphasized that the biomedical approach is flawed because the body alone does not contribute to illness. Instead, the individual mind (psychological and social factors) play a significant role in how an illness is caused and how it is treated. Engel proposed a dialogue between the patient and the doctor in order to find the most effective treatment solution. George L. Engel and John Romano of the
University of Rochester The University of Rochester is a private university, private research university in Rochester, New York, United States. It was founded in 1850 and moved into its current campus, next to the Genesee River in 1930. With approximately 30,000 full ...
in 1977, are widely credited with being the first to propose a biopsychosocial model. Engel struggled with the then-prevailing biomedical approach to medicine as he strove for a more holistic approach by recognizing that each patient has their own thoughts, feelings, and history. In developing his model, Engel framed it for both illnesses and psychological problems.


Emergence within the context of psychiatry

The biopsychosocial model is not just one of many competing possibilities - another intelligently constructed explanation of health. Its emergence is best understood within a historical context. The biopsychosocial model's emergence in psychiatry was influenced by the credibility problem in psychiatry as a medical specialism that arose during wartime conditions. By the 20th century, psychiatry was still a relatively new field. In the
Victorian era In the history of the United Kingdom and the British Empire, the Victorian era was the reign of Queen Victoria, from 20 June 1837 until her death on 22 January 1901. Slightly different definitions are sometimes used. The era followed the ...
, psychiatry was faced with two key challenges: firstly, taking control of the asylum system from lay administrators and secondly, constructing a credible knowledge base for medical authority over mental illness. At the time, the solution to this was developing a rhetoric of justification for psychiatry which was that the brain is the root of insanity, and physicians are the guardians of mental health. This position both reflected and contributed to the rise of
eugenics Eugenics is a set of largely discredited beliefs and practices that aim to improve the genetic quality of a human population. Historically, eugenicists have attempted to alter the frequency of various human phenotypes by inhibiting the fer ...
thought in western intellectual culture. However, this was challenged by the shellshock problem after
World War I World War I or the First World War (28 July 1914 – 11 November 1918), also known as the Great War, was a World war, global conflict between two coalitions: the Allies of World War I, Allies (or Entente) and the Central Powers. Fighting to ...
– there was a fundamental incompatibility between a eugenic view of lunacy and the sad reality of respectable men breaking down with predictable regularity in the war trenches. This led to the recognition of neurosis and acceptance of
psychoanalysis PsychoanalysisFrom Greek language, Greek: and is a set of theories and techniques of research to discover unconscious mind, unconscious processes and their influence on conscious mind, conscious thought, emotion and behaviour. Based on The Inte ...
in psychiatric discourse. A year after the end of the war, the British Psychoanalytical Society and the Medical Section of the British Psychological Society were both established, marking the start of a nuanced interplay between biological psychiatry and medical psychotherapy. The Tavistock Clinic played a significant role in bridging the gap between these approaches and favoured a unified psychosomatic approach. Under these conditions, the biopsychosocial model was set up to revolutionise our understanding of psychiatry and health.


WHO adoption in 2002

After publication, the biopsychosocial model was adopted by the
World Health Organization The World Health Organization (WHO) is a list of specialized agencies of the United Nations, specialized agency of the United Nations which coordinates responses to international public health issues and emergencies. It is headquartered in Gen ...
(WHO) in 2002 as a basis for the International Classification of Function.


References

{{reflist Interdisciplinary branches of psychology