Benzopyrone may refer to either of two
ketone
In organic chemistry, a ketone is a functional group with the structure R–C(=O)–R', where R and R' can be a variety of carbon-containing substituents. Ketones contain a carbonyl group –C(=O)– (which contains a carbon-oxygen double bon ...
derivatives of
benzopyran which constitute the core skeleton of many flavonoid compounds:
*
Chromone (1-benzopyran-4-one)
*
Coumarin
Coumarin () or 2''H''-chromen-2-one is an aromatic organic chemical compound with formula . Its molecule can be described as a benzene molecule with two adjacent hydrogen atoms replaced by a lactone-like chain , forming a second six-membered ...
(1-benzopyran-2-one)
Certain simple benzopyrones have clinical medical value as an edema modifiers.
Coumarin
Coumarin () or 2''H''-chromen-2-one is an aromatic organic chemical compound with formula . Its molecule can be described as a benzene molecule with two adjacent hydrogen atoms replaced by a lactone-like chain , forming a second six-membered ...
and other benzopyrones, such as 5,6 benzopyrone, 1,2 benzopyrone,
diosmin and others are known to stimulate macrophages to degrade extracellular albumin, allowing faster resorption of edematous fluids.
Review of benzypyrone drugs and edema
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Naturally occurring coumarin is also the basis for various 4-hydroxybenzopyrone-based molecules which occur naturally dicoumarol
Dicoumarol (INN) or dicumarol ( USAN) is a naturally occurring anticoagulant drug that depletes stores of vitamin K (similar to warfarin, a drug that dicoumarol inspired). It is also used in biochemical experiments as an inhibitor of reductases. ...
and are made synthetically warfarin
Warfarin, sold under the brand name Coumadin among others, is a medication that is used as an anticoagulant (blood thinner). It is commonly used to prevent blood clots such as deep vein thrombosis and pulmonary embolism, and to prevent ...
and function as anticoagulants.
References
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Benzopyrans