Bay R 1531, also known as LY-197206, is a
tricyclic tryptamine derivative
In mathematics, the derivative is a fundamental tool that quantifies the sensitivity to change of a function's output with respect to its input. The derivative of a function of a single variable at a chosen input value, when it exists, is t ...
. It acts as a
selective serotonin 5-HT1A receptor agonist
An agonist is a chemical that activates a Receptor (biochemistry), receptor to produce a biological response. Receptors are Cell (biology), cellular proteins whose activation causes the cell to modify what it is currently doing. In contrast, an R ...
. It was investigated unsuccessfully for the treatment of
stroke
Stroke is a medical condition in which poor cerebral circulation, blood flow to a part of the brain causes cell death. There are two main types of stroke: brain ischemia, ischemic, due to lack of blood flow, and intracranial hemorrhage, hemor ...
but continues to be used in
scientific research.
It shows very high
affinity for the serotonin 5-HT
1A receptor (K
i = 1.3nM).
See also
*
Partial lysergamide
*
8-OH-DPAT
8-OH-DPAT is a research chemical of the aminotetralin chemical class which was developed in the 1980s and has been widely used to study the function of the 5-HT1A receptor, 5-HT1A receptor. It was one of the first major 5-HT1A receptor full agonis ...
*
RDS-127
RDS-127 is a drug which is used in scientific research. It acts as a D2-like receptor agonist and also has some serotonin and adrenergic agonist effects, as well as some anticholinergic action, and produces both anorectic and pro-sexual eff ...
*
RU-27849
*
RU-28306
*
LY-178210
*
LY-293,284
*
NDTDI
*
''N''-DEAOP-NMT
*
CT-5252
References
{{Tryptamines
Alpha-Alkyltryptamines
N,N-Dialkyltryptamines
Heterocyclic compounds with 3 rings
5-Methoxytryptamines
Partial ergolines
Serotonin receptor agonists