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A band cell (also called band neutrophil, band form or stab cell) is a cell undergoing
/ref> An excess may sometimes be referred to as bandemia.
File:Band neutrophil.JPG, Band neutrophil in peripheral
Histology at okstate.edu
* ttps://web.archive.org/web/20070311085356/http://usuarios.lycos.es/biologiacelular/Medula%20osea%20hemopoiesis18.htm Interactive diagram at lycos.es Histology {{developmental-biology-stub
A band cell (also called band neutrophil, band form or stab cell) is a cell undergoing granulopoiesis
Granulopoiesis (or granulocytopoiesis) is a part of haematopoiesis, that leads to the production of granulocytes. A granulocyte, also referred to as a polymorphonuclear leukocyte (PMN), is a type of white blood cell that has multi lobed nucle ...
, derived from a metamyelocyte
A metamyelocyte is a cell undergoing granulopoiesis, derived from a myelocyte, and leading to a band cell.
It is characterized by the appearance of a bent nucleus, cytoplasmic granules, and the absence of visible nucleoli. (If the nucleus is no ...
, and leading to a mature granulocyte
Granulocytes are
cells in the innate immune system characterized by the presence of specific granules in their cytoplasm. Such granules distinguish them from the various agranulocytes. All myeloblastic granulocytes are polymorphonuclear. They ...
.
It is characterized by having a curved but not lobular nucleus
Nucleus ( : nuclei) is a Latin word for the seed inside a fruit. It most often refers to:
*Atomic nucleus, the very dense central region of an atom
* Cell nucleus, a central organelle of a eukaryotic cell, containing most of the cell's DNA
Nucl ...
.
The term "band cell" implies a granulocytic lineage (e.g., neutrophils).
Clinical significance
Band neutrophils are an intermediary step prior to the complete maturation of segmented neutrophils. Polymorphonuclear neutrophils are initially released from the bone marrow as band cells, as the immature neutrophils become activated or exposed to pathogens, their nucleus will take on a segmented appearance. An increase in the number of these immature neutrophils in circulation can be indicative of a infection for which they are being called to fight against, or some inflammatory process. The increase of band cells in the circulation is called bandemia and is a "left shift" process. Blood reference ranges for neutrophilic band cells in adults are 3 to 5% ofwhite blood cell
White blood cells, also called leukocytes or leucocytes, are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders. All white blood cells are produced and derived from mult ...
s,Last page of or up to 0.7 x109/L.Clinical Laboratory Medicine. By Kenneth D. McClatchey. Page 807./ref> An excess may sometimes be referred to as bandemia.
See also
*Pluripotential hemopoietic stem cell
Hematopoietic stem cells (HSCs) are the stem cells that give rise to other blood cells. This process is called haematopoiesis. In vertebrates, the very first definitive HSCs arise from the ventral endothelial wall of the embryonic aorta within ...
Additional images
blood film
A blood smear, peripheral blood smear or blood film is a thin layer of blood smeared on a glass microscope slide and then stained in such a way as to allow the various blood cells to be examined microscopically. Blood smears are examined in the ...
File:Hematopoiesis (human) diagram en.svg, Hematopoiesis
References
External links
* - "Bone Marrow and Hemopoiesis: bone marrow smear, neutrophil series" * *Histology at okstate.edu
* ttps://web.archive.org/web/20070311085356/http://usuarios.lycos.es/biologiacelular/Medula%20osea%20hemopoiesis18.htm Interactive diagram at lycos.es Histology {{developmental-biology-stub