BJ Casey
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Betty Jo "BJ" Casey is an American cognitive neuroscientist and expert on adolescent
brain development The brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals. It consists of nervous tissue and is typically located in the head ( cephalization), usually near organs for special sens ...
and
self control Self-control is an aspect of inhibitory control, one of the core executive functions. Executive functions are cognitive processes that are necessary for regulating one's behavior in order to achieve specific goals. Defined more independen ...
. She is the Christina L. Williams Professor of Neuroscience at
Barnard College of Columbia University Barnard College is a private women's liberal arts college affiliated with Columbia University in New York City. It was founded in 1889 by a group of women led by young student activist Annie Nathan Meyer, who petitioned Columbia University's ...
where she directs the Fundamentals of the Adolescent Brain (FAB) Lab and is an Affiliated Professor of the Justice Collaboratory at
Yale Law School Yale Law School (YLS) is the law school of Yale University, a Private university, private research university in New Haven, Connecticut. It was established in 1824. The 2020–21 acceptance rate was 4%, the lowest of any law school in the United ...
,
Yale University Yale University is a Private university, private Ivy League research university in New Haven, Connecticut, United States. Founded in 1701, Yale is the List of Colonial Colleges, third-oldest institution of higher education in the United Stat ...
. Casey has served on several national and international advisory boards and has won numerous honors and awards for her scientific discoveries that have been featured in several media outlets such as ''
National Geographic ''National Geographic'' (formerly ''The National Geographic Magazine'', sometimes branded as ''Nat Geo'') is an American monthly magazine published by National Geographic Partners. The magazine was founded in 1888 as a scholarly journal, nine ...
'', ''
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'', and ''
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''.


Biography

Casey was born in
Kinston, North Carolina Kinston is a city in Lenoir County, North Carolina, United States, with a population of 19,900 as of the 2020 United States census, 2020 census. It has been the county seat of Lenoir County since its formation in 1791. Kinston is located in the ...
and grew up on a small family farm. She was the first in her family to obtain an advanced degree, earning her bachelor's and master's degrees in psychology from
Appalachian State University Appalachian State University (), or App State, is a Public university, public research university in Boone, North Carolina, United States. It was founded as a normal school, teachers' college in 1899 by brothers B. B. and D. D. Dougherty and th ...
and her doctorate in experimental psychology and behavioral neuroscience from the
University of South Carolina The University of South Carolina (USC, SC, or Carolina) is a Public university, public research university in Columbia, South Carolina, United States. Founded in 1801 as South Carolina College, It is the flagship of the University of South Car ...
. During her postdoctoral fellowship at the
National Institute of Mental Health The National Institute of Mental Health (NIMH) is one of 27 institutes and centers that make up the National Institutes of Health (NIH). The NIH, in turn, is an agency of the United States Department of Health and Human Services and is the primar ...
, Casey learned about
functional magnetic resonance imaging Functional magnetic resonance imaging or functional MRI (fMRI) measures brain activity by detecting changes associated with blood flow. This technique relies on the fact that cerebral blood flow and neuronal activation are coupled. When an area o ...
(fMRI), which offered a glimpse into the functioning human brain non-invasively. She was among the first scientists to use fMRI in children, laying the groundwork for a new field of study:
developmental cognitive neuroscience Developmental cognitive neuroscience is an interdisciplinary scientific field devoted to understanding psychological processes and their neurological bases in the developing organism. It examines how the mind changes as children grow up, interrelat ...
. Following her postdoc, she was an assistant professor at the
University of Pittsburgh Medical Center UPMC is an American integrated delivery system, integrated global nonprofit health enterprise that has 100,000 employees, 40 hospitals with more than 8,000 licensed beds, 800 clinical locations including outpatient sites and doctors' offices, a ...
and a Visiting Research Collaborator at
Princeton University Princeton University is a private university, private Ivy League research university in Princeton, New Jersey, United States. Founded in 1746 in Elizabeth, New Jersey, Elizabeth as the College of New Jersey, Princeton is the List of Colonial ...
. She was then recruited by Michael Posner to direct the Sackler Institute for Developmental Psychobiology. During this time, she held the position of associate professor and professor of psychology in Psychiatry and Neuroscience at
Weill Cornell Medicine Weill Cornell Medicine (; officially Joan and Sanford I. Weill Medical College of Cornell University), originally Cornell University Medical College, is the medical school of Cornell University, located on the Upper East Side of Manhattan in Ne ...
and Visiting Researcher at
Rockefeller University The Rockefeller University is a Private university, private Medical research, biomedical Research university, research and graduate-only university in New York City, New York. It focuses primarily on the biological and medical sciences and pro ...
. Casey also served as the Director of the Neuroscience Graduate Program at Weill Cornell for five years. In 2016, Casey moved to Yale University as a professor in the Department of Psychology, an affiliate professor of Interdepartmental Neuroscience Program of
Yale School of Medicine The Yale School of Medicine is the medical school of Yale University, a private research university in New Haven, Connecticut. It was founded in 1810 as the Medical Institution of Yale College and formally opened in 1813. It is the sixth-oldest m ...
and affiliate professor of the Justice Collaboratory at
Yale Law School Yale Law School (YLS) is the law school of Yale University, a Private university, private research university in New Haven, Connecticut. It was established in 1824. The 2020–21 acceptance rate was 4%, the lowest of any law school in the United ...
. Casey returned to New York in 2022 as the Christina L. Williams Professor of Neuroscience at
Barnard College of Columbia University Barnard College is a private women's liberal arts college affiliated with Columbia University in New York City. It was founded in 1889 by a group of women led by young student activist Annie Nathan Meyer, who petitioned Columbia University's ...
where she currently directs the Fundamentals of the Adolescent Brain (FAB) lab. Casey has served on several national advisory boards, including the
National Institute of Mental Health The National Institute of Mental Health (NIMH) is one of 27 institutes and centers that make up the National Institutes of Health (NIH). The NIH, in turn, is an agency of the United States Department of Health and Human Services and is the primar ...
(NIMH) Board of Scientific Counselors and NIMH Council, the Scientific Advisory Board for the National Alliance for Research on Schizophrenia & Depression (
NARSAD The Brain & Behavior Research Foundation (BBRF) is a nonprofit 501(c)(3) organization that funds mental health research. It was originally called the National Alliance for Research on Schizophrenia & Depression, or NARSAD. It received its nonpro ...
), Advisory Board for the
Human Connectome Project The Human Connectome Project (HCP) was a five-year project (later extended to 10 years) sponsored by sixteen components of the National Institutes of Health, split between two consortia of research institutions. The project was launched in July 20 ...
- Life Span Study, the National Research Council Board on Children, Youth and Families, and National Research Council and Institute of Medicine committees of the National Academies on the Science of Adolescent Risk Taking, Assessing Juvenile Justice Reform, and Sports Related Concussions in Youth.


Research

Casey is one of the most cited scientists in developmental neuroscience, with over 250 publications and over 80,000 citations. Over the course of her career, her work has spanned a range of topics across human development from visual attention in infants, to adolescent development, and the subsequent transition into early adulthood. In addition to using fMRI to examine typical and atypical brain and behavioral development, Casey has studied both humans and genetically altered mice in her research. Her work has demonstrated similar patterns of behavior and brain activity during adolescence across species. Casey proposed a prominent model of adolescent neurobiology known as the imbalance model, a foundational theory for many developmental neuroscience studies in humans and in animals. This model posits that dynamic changes in brain structure and function during adolescence lead to transient imbalances in how brain areas communicate that impact emotion reactivity and regulation during adolescence, relative to earlier and later developmental stages. In collaboration with the late
Walter Mischel Walter Mischel (; February 22, 1930 – September 12, 2018) was an Austrian-born American psychologist specializing in personality theory and social psychology. He was the Robert Johnston Niven Professor of Humane Letters in the Department ...
, Casey studied the original participants of Mischel's famous 1972 Stanford Bing Nursery School " Marshmallow Experiment" 40 years later. The study's findings suggested that individual differences in self-control seen in early childhood may be predictive of motivational processes and cognitive control in adulthood. During Casey's 15-year tenure as the director of the Sackler Institute for Developmental Psychobiology, she cultivated the institute's world-renowned reputation, bringing in numerous training and center grants from the
National Institutes of Health The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research. It was founded in 1887 and is part of the United States Department of Health and Human Service ...
,
National Science Foundation The U.S. National Science Foundation (NSF) is an Independent agencies of the United States government#Examples of independent agencies, independent agency of the Federal government of the United States, United States federal government that su ...
, the John Merck Fund, the
Dana Foundation The Dana Foundation (Charles A. Dana Foundation) is a private philanthropic organization based in New York dedicated to advancing neuroscience and society by supporting cross-disciplinary intersections such as neuroscience and ethics, law, poli ...
, and the
MacArthur Foundation The John D. and Catherine T. MacArthur Foundation is a private foundation that makes grants and impact investments to support non-profit organizations in approximately 117 countries around the world. It has an endowment of $7.6 billion and ...
. Among these are two approximately $10 million grants from the
National Institutes of Health The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research. It was founded in 1887 and is part of the United States Department of Health and Human Service ...
. From 2008 to 2013, one of these awards funded the Center for Brain, Gene, and Behavioral (CBGB) Research Across Development, which aimed to examine how brain-derived neurotrophic factor (
BDNF Brain-derived neurotrophic factor (BDNF), or abrineurin, is a protein found in the and the periphery. that, in humans, is encoded by the ''BDNF'' gene. BDNF is a member of the neurotrophin family of growth factors, which are related to the cano ...
) influenced learning and responses to stress across development. In 2015, the
National Institutes of Health The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research. It was founded in 1887 and is part of the United States Department of Health and Human Service ...
funded the Adolescent Brain Cognitive Development (ABCD) Study®, the largest long-term study of child and adolescent health and brain development in the United States. Casey was awarded a grant of over $20 million as Principal Investigator of the ABCD Study Yale University site.


Mentoring and training

Casey directed the John Merck Fund Summer Institute on the Biology of Developmental Disabilities from 2001 to 2010 and then the Mortimer D. Sackler, M.D. Summer Institute on Translational Developmental Neuroscience from 2012 to 2016, both specialized training courses in developmental science for graduate students, postdocs, and early career faculty. Casey has formally mentored over 30 pre and post doctoral trainees. Her trainees include Adriana Galván, Catherine Hartley, Leah Somerville, and Nim Tottenham. She has received lifetime achievement awards for her scientific discoveries and mentoring, especially of women in science from the Association of Psychological Science in 2021 and from the Society of Neuroscience in 2023.


Public engagement

Casey is a member of the MacArthur Foundation Research Network on Law and Neuroscience and has been called upon as an expert in adolescent brain development in both the scientific and legal arenas. Her research was included in amicus briefs presented to the U.S. Supreme Court to argue against the death penalty in juveniles (''Roper v. Simmons'', 2005) and mandatory life without parole (''Graham v. Florida'', 2010; ''Miller v. Alabama'', 2012).


Awards and honors

* 2014, Honorary doctorate,
Utrecht University Utrecht University (UU; , formerly ''Rijksuniversiteit Utrecht'') is a public university, public research university in Utrecht, Netherlands. Established , it is one of the oldest universities in the Netherlands. In 2023, it had an enrollment of ...
* 2015, Ruane Prize for Outstanding Achievement in Child and Adolescent Psychiatric Research, Brain & Behavior Research Foundation * 2016, Healthcare and Life Sciences 50, ''
Irish America ''Irish America'' is a bi-monthly periodical that aims to cover topics relevant to the Irish in North America including a range of political, economic, social, and cultural themes. The magazine’s inaugural issue was published in October 1985. ...
'' magazine * 2017, Distinguished Scholar Award, Social Affective Neuroscience Society * 2019, Flux Huttenlocher Award, The Society for Developmental Cognitive Neuroscience * 2021, Association for Psychological Science Lifetime Achievement Mentor Award * 2021, Elected to the American Academy of Arts and Sciences * 2022, American Psychological Association Distinguished Scientific Contribution Award * 2022, George A. Miller Prize in Cognitive Neuroscience, Cognitive Neuroscience Society * 2023, Mika Salpeter Lifetime Achievement Award, Society for Neuroscience * 2025, Elected to the National Academy of Sciences


Selected publications

* * * * * * * * * * *


References


External links


Research , FABLAB , Barnard College-Columbia University

BJ Casey , Department of Neuroscience

BJ Casey , Department of PsychologyBJ Casey
publications indexed by
Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of Academic publishing, scholarly literature across an array of publishing formats and disciplines. Released in Beta release, beta in November 2004, th ...
{{DEFAULTSORT:Casey, BJ Yale University faculty Living people American women psychologists 21st-century American psychologists American neuroscientists Appalachian State University alumni University of South Carolina alumni Adolescence Year of birth missing (living people) American women academics 21st-century American women scientists APA Distinguished Scientific Award for an Early Career Contribution to Psychology recipients