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Functional Magnetic Resonance Imaging
Functional magnetic resonance imaging or functional MRI (fMRI) measures brain activity by detecting changes associated with blood flow. This technique relies on the fact that cerebral blood flow and neuronal activation are coupled. When an area of the brain is in use, blood flow to that region also increases. The primary form of fMRI uses the blood-oxygen-level dependent (BOLD) contrast, discovered by Seiji Ogawa in 1990. This is a type of specialized brain and body scan used to map neuron, neural activity in the brain or spinal cord of humans or other animals by imaging the change in blood flow (hemodynamic response) related to energy use by brain cells. Since the early 1990s, fMRI has come to dominate brain mapping research because it does not involve the use of injections, surgery, the ingestion of substances, or exposure to ionizing radiation. This measure is frequently corrupted by noise from various sources; hence, statistical procedures are used to extract the underlying si ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blood Flow
Hemodynamics American and British English spelling differences#ae and oe, or haemodynamics are the Fluid dynamics, dynamics of blood flow. The circulatory system is controlled by homeostasis, homeostatic mechanisms of autoregulation, just as hydraulic circuits are controlled by control systems. The hemodynamic response continuously monitors and adjusts to conditions in the body and its environment. Hemodynamics explains the physical laws that govern the flow of blood in the blood vessels. Blood flow ensures the transportation of nutrients, hormones, metabolic waste products, oxygen, and carbon dioxide throughout the body to maintain cell-level metabolism, the regulation of the pH, osmotic pressure and temperature of the whole body, and the protection from microbial and mechanical harm. Blood is a non-Newtonian fluid, and is most efficiently studied using rheology rather than hydrodynamics. Because blood vessels are not rigid tubes, classic hydrodynamics and fluids mechanics based o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hemoglobin
Hemoglobin (haemoglobin, Hb or Hgb) is a protein containing iron that facilitates the transportation of oxygen in red blood cells. Almost all vertebrates contain hemoglobin, with the sole exception of the fish family Channichthyidae. Hemoglobin in the blood carries oxygen from the respiratory organs (lungs or gills) to the other tissues of the body, where it releases the oxygen to enable aerobic respiration which powers an animal's metabolism. A healthy human has 12to 20grams of hemoglobin in every 100mL of blood. Hemoglobin is a metalloprotein, a chromoprotein, and a globulin. In mammals, hemoglobin makes up about 96% of a red blood cell's dry matter, dry weight (excluding water), and around 35% of the total weight (including water). Hemoglobin has an oxygen-binding capacity of 1.34mL of O2 per gram, which increases the total blood oxygen capacity seventy-fold compared to dissolved oxygen in blood plasma alone. The mammalian hemoglobin molecule can bind and transport up to four ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Paradigm
In science and philosophy, a paradigm ( ) is a distinct set of concepts or thought patterns, including theories, research methods, postulates, and standards for what constitute legitimate contributions to a field. The word ''paradigm'' is Ancient Greek, Greek in origin, meaning "pattern". Etymology ''Paradigm'' comes from Greek παράδειγμα (''paradeigma''); "pattern, example, sample"; from the verb παραδείκνυμι (''paradeiknumi''); "exhibit, represent, expose"; and that from παρά (''para''); "beside, beyond"; and δείκνυμι (''deiknumi''); "to show, to point out". In classical (Greek-based) rhetoric, a paradeigma aims to provide an audience with an illustration of a similar occurrence. This illustration is not meant to take the audience to a conclusion; however, it is used to help guide them to get there. One way of how a ''paradeigma'' is meant to guide an audience would be exemplified by the role of a personal accountant. It is not the job of a p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Signal-to-noise Ratio
Signal-to-noise ratio (SNR or S/N) is a measure used in science and engineering that compares the level of a desired signal to the level of background noise. SNR is defined as the ratio of signal power to noise power, often expressed in decibels. A ratio higher than 1:1 (greater than 0 dB) indicates more signal than noise. SNR is an important parameter that affects the performance and quality of systems that process or transmit signals, such as communication systems, audio systems, radar systems, imaging systems, and data acquisition systems. A high SNR means that the signal is clear and easy to detect or interpret, while a low SNR means that the signal is corrupted or obscured by noise and may be difficult to distinguish or recover. SNR can be improved by various methods, such as increasing the signal strength, reducing the noise level, filtering out unwanted noise, or using error correction techniques. SNR also determines the maximum possible amount of data that ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Variable (research)
In science and research, an attribute is a quality of an object (person, thing, etc.). Earl R. Babbie, ''The Practice of Social Research'', 12th edition, Wadsworth Publishing, 2009, , p. 14-18 Attributes are closely related to variables. A variable is a logical set of attributes. Variables can "vary" – for example, be high or low. How high, or how low, is determined by the value of the attribute (and in fact, an attribute could be just the word "low" or "high"). ''(For example see: Binary option)'' While an attribute is often intuitive, the variable is the operationalized way in which the attribute is represented for further data processing. In data processing data are often represented by a combination of ''items'' (objects organized in rows), and multiple variables (organized in columns). Values of each variable statistically "vary" (or are distributed) across the variable's domain. A domain is a set of all possible values that a variable is allowed to have. The values are o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stefano Sandrone
Stefano Sandrone (born 1988) is an Italian neuroscientist, an educationalist and a principal teaching fellow at Imperial College London. Life and works Stefano Sandrone was born in Canelli, Italy, on 1 February 1988, and obtained a Ph.D. in Neuroscience at King's College London, United Kingdom, where he started his career as a teaching fellow. In 2014 he was selected as a young scientist for the 64th Lindau Nobel Laureate Meeting in Physiology or Medicine, which was attended by 37 Nobel Laureates, and appeared in ''Wired'' magazine's list of the 'most promising Italians under 35’. In 2015 he co-authored the book entitled '' Brain Renaissance'', and, for this, he won the biennial Award for Outstanding Book in the History of the Neurosciences presented by the International Society for the History of the Neurosciences. He also appeared as a contributor to the 41st edition of the ''Gray's Anatomy''. In 2016 Sandrone was awarded the H. Richard Tyler Award presented by the Ameri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Experiments
An experiment is a procedure carried out to support or refute a hypothesis, or determine the efficacy or likelihood of something previously untried. Experiments provide insight into Causality, cause-and-effect by demonstrating what outcome occurs when a particular factor is manipulated. Experiments vary greatly in goal and scale but always rely on repeatable procedure and logical analysis of the results. There also exist natural experiment, natural experimental studies. A child may carry out basic experiments to understand how things fall to the ground, while teams of scientists may take years of systematic investigation to advance their understanding of a phenomenon. Experiments and other types of hands-on activities are very important to student learning in the science classroom. Experiments can raise test scores and help a student become more engaged and interested in the material they are learning, especially when used over time. Experiments can vary from personal and i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
William James
William James (January 11, 1842 – August 26, 1910) was an American philosopher and psychologist. The first educator to offer a psychology course in the United States, he is considered to be one of the leading thinkers of the late 19th century, one of the most influential philosophers and is often dubbed the "father of American psychology." Born into a wealthy family, James was the son of the Swedenborgian theologian Henry James Sr. and the brother of both the prominent novelist Henry James and the diarist Alice James. James trained as a physician and taught anatomy at Harvard, but never practiced medicine. Instead, he pursued his interests in psychology and then philosophy. He wrote widely on many topics, including epistemology, education, metaphysics, psychology, religion, and mysticism. Among his most influential books are '' The Principles of Psychology'', a groundbreaking text in the field of psychology; '' Essays in Radical Empiricism'', an important text in phil ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blood
Blood is a body fluid in the circulatory system of humans and other vertebrates that delivers necessary substances such as nutrients and oxygen to the cells, and transports metabolic waste products away from those same cells. Blood is composed of blood cells suspended in blood plasma. Plasma, which constitutes 55% of blood fluid, is mostly water (92% by volume), and contains proteins, glucose, mineral ions, and hormones. The blood cells are mainly red blood cells (erythrocytes), white blood cells (leukocytes), and (in mammals) platelets (thrombocytes). The most abundant cells are red blood cells. These contain hemoglobin, which facilitates oxygen transport by reversibly binding to it, increasing its solubility. Jawed vertebrates have an adaptive immune system, based largely on white blood cells. White blood cells help to resist infections and parasites. Platelets are important in the clotting of blood. Blood is circulated around the body through blood vessels by the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Angelo Mosso
Angelo Mosso (30 May 1846 – 24 November 1910) was a 19th-century Italian physiologist who invented the first neuroimaging technique, known as 'human circulation balance'. Mosso began his groundbreaking work by recording the pulsations of the human cortex in patients with skull defects following neurosurgical procedures. He observed that these pulsations changed during mental activity, leading him to infer that blood flow to the brain increases during such activities. To non-invasively measure the redistribution of blood during emotional and intellectual activity in healthy subjects, Mosso invented the 'human circulation balance'. This invention is regarded as the first neuroimaging technique ever and is a forerunner of more refined techniques like functional magnetic resonance imaging (Functional magnetic resonance imaging, fMRI) and positron emission tomography (Positron Emission Topography, PET). Born in Turin, Mosso studied medicine in Turin, Florence, Leipzig, and Paris. H ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Michael Faraday
Michael Faraday (; 22 September 1791 – 25 August 1867) was an English chemist and physicist who contributed to the study of electrochemistry and electromagnetism. His main discoveries include the principles underlying electromagnetic induction, diamagnetism, and electrolysis. Although Faraday received little formal education, as a self-made man, he was one of the most influential scientists in history. It was by his research on the magnetic field around a Electrical conductor, conductor carrying a direct current that Faraday established the concept of the electromagnetic field in physics. Faraday also established that magnetism could Faraday effect, affect rays of light and that there was an underlying relationship between the two phenomena. the 1911 ''Encyclopædia Britannica''. He similarly discovered the principles of electromagnetic induction, diamagnetism, and the Faraday's laws of electrolysis, laws of electrolysis. His inventions of electric motor, electromagnetic rotar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diamagnetism
Diamagnetism is the property of materials that are repelled by a magnetic field; an applied magnetic field creates an induced magnetic field in them in the opposite direction, causing a repulsive force. In contrast, paramagnetic and ferromagnetic materials are attracted by a magnetic field. Diamagnetism is a quantum mechanical effect that occurs in all materials; when it is the only contribution to the magnetism, the material is called diamagnetic. In paramagnetic and ferromagnetic substances, the weak diamagnetic force is overcome by the attractive force of magnetic dipoles in the material. The Permeability (electromagnetism), magnetic permeability of diamagnetic materials is less than the Vacuum_permeability, permeability of vacuum, ''μ''0. In most materials, diamagnetism is a weak effect which can be detected only by sensitive laboratory instruments, but a superconductivity, superconductor acts as a strong diamagnet because it entirely expels any magnetic field from its inter ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
