The anterior perforated substance is a part of the

brain The brain is an organ (biology), organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals. It consists of nervous tissue and is typically located in the head (cephalization), usually near organs for ...

. It is bilateral. It is irregular and quadrilateral. It lies in front of the

optic tract In neuroanatomy, the optic tract () is a part of the visual system in the brain. It is a continuation of the optic nerve that relays information from the optic chiasm to the ipsilateral lateral geniculate nucleus (LGN), pretectal nuclei, and su ...

and behind the olfactory trigone.

Structure

The anterior perforated substance is bilateral. It lies in front of the

. It lies behind the olfactory trigone, separated by the fissure prima. Medially and in front, it is continuous with the subcallosal gyrus. Laterally, it is bounded by the lateral stria of the olfactory tract, and is continued into the uncus. Its gray substance is confluent above with that of the corpus striatum, and is perforated anteriorly by numerous small blood vessels that supply such areas as the

internal capsule The internal capsule is a paired white matter structure, as a two-way nerve tract, tract, carrying afferent nerve fiber, ascending and efferent nerve fiber, descending axon, fibers, to and from the cerebral cortex. The internal capsule is situate ...

. The

anterior cerebral artery The anterior cerebral artery (ACA) is one of a pair of cerebral arteries that supplies oxygenated blood to most midline portions of the frontal lobes and superior medial parietal lobes of the brain. The two anterior cerebral arteries arise from th ...

arises just below the anterior perforated substance. The

middle cerebral artery The middle cerebral artery (MCA) is one of the three major paired cerebral artery, cerebral arteries that supply blood to the cerebrum. The MCA arises from the internal carotid artery and continues into the lateral sulcus where it then branches an ...

passes through its lateral two thirds.

Blood supply

The anterior perforated substance is supplied by lenticulostriate arteries, which branch from the

. It is also supplied by anterior choroidal artery. Small branches from these create holes, which give the anterior perforated substance its name.

History

The anterior perforated substance is named after the holes created by small

blood vessels Blood vessels are the tubular structures of a circulatory system that transport blood throughout many animals’ bodies. Blood vessels transport blood cells, nutrients, and oxygen to most of the tissues of a body. They also take waste an ...

that supply it.

Additional images

File:Human brainstem anterior view 2 description.JPG, Human brainstem anterior view File:Slide2ZEB.JPG, Cerebrum. Inferior view. Deep dissection

References

External links

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Interpeduncular fossa The interpeduncular fossa is a deep depression of the ventral surface of the midbrain between the two cerebral crus, cerebal crura. It has been found in humans and macaques, but not in rats or mice, showing that this is a relatively new evolutiona ...

" (#6)
Photo at umdnj.edu

NIF Search - Anterior perforated substance
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Neuroscience Information Framework The Neuroscience Information Framework is a repository of global neuroscience web resources, including experimental, clinical, and translational neuroscience databases, knowledge bases, atlases, and genetic/ genomic resources and provides many aut ...