The anterior perforated substance is a part of the

brain The brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals. It consists of nervous tissue and is typically located in the head ( cephalization), usually near organs for special ...

. It is

bilateral Bilateral may refer to any concept including two sides, in particular: *Bilateria, bilateral animals *Bilateralism, the political and cultural relations between two states *Bilateral, occurring on both sides of an organism ( Anatomical terms of l ...

. It is irregular and quadrilateral. It lies in front of the

optic tract In neuroanatomy, the optic tract () is a part of the visual system in the brain. It is a continuation of the optic nerve that relays information from the optic chiasm to the ipsilateral lateral geniculate nucleus (LGN), pretectal nuclei, and supe ...

and behind the olfactory trigone.

Structure

The anterior perforated substance is

. It lies in front of the

. It lies behind the olfactory trigone, separated by the

fissure prima A fissure is a long, narrow crack opening along the surface of Earth. The term is derived from the Latin word , which means 'cleft' or 'crack'. Fissures emerge in Earth's crust, on ice sheets and glaciers, and on volcanoes. Ground fissure ...

. Medially and in front, it is continuous with the

subcallosal gyrus The subcallosal gyrus (paraterminal gyrus, peduncle of the corpus callosum) is a narrow lamina on the medial surface of the hemisphere in front of the lamina terminalis, behind the parolfactory area, and below the rostrum of the corpus callosum. I ...

. Laterally, it is bounded by the lateral stria of the

olfactory tract The olfactory tract is a bilateral bundle of afferent nerve fibers from the mitral and tufted cells of the olfactory bulb that connects to several target regions in the brain, including the piriform cortex, amygdala, and entorhinal cortex. It ...

, and is continued into the

uncus The uncus is an anterior extremity of the parahippocampal gyrus. It is separated from the apex of the temporal lobe by a slight fissure called the incisura temporalis (also called rhinal sulcus). Although superficially continuous with the hipp ...

. Its

gray substance Grey matter is a major component of the central nervous system, consisting of neuronal cell bodies, neuropil (dendrites and unmyelinated axons), glial cells ( astrocytes and oligodendrocytes), synapses, and capillaries. Grey matter is dist ...

is confluent above with that of the

corpus striatum The striatum, or corpus striatum (also called the striate nucleus), is a nucleus (a cluster of neurons) in the subcortical basal ganglia of the forebrain. The striatum is a critical component of the motor and reward systems; receives glutamate ...

, and is perforated anteriorly by numerous small blood vessels that supply such areas as the

internal capsule The internal capsule is a white matter structure situated in the inferomedial part of each cerebral hemisphere of the brain. It carries information past the basal ganglia, separating the caudate nucleus and the thalamus from the putamen and the g ...

. The

anterior cerebral artery The anterior cerebral artery (ACA) is one of a pair of cerebral arteries that supplies oxygenated blood to most midline portions of the frontal lobes and superior medial parietal lobes of the brain. The two anterior cerebral arteries arise from ...

arises just below the anterior perforated substance. The

middle cerebral artery The middle cerebral artery (MCA) is one of the three major paired cerebral arteries that supply blood to the cerebrum. The MCA arises from the internal carotid artery and continues into the lateral sulcus where it then branches and projects to man ...

passes through its lateral two thirds.

Blood supply

The anterior perforated substance is supplied by

lenticulostriate arteries The lenticulostriate arteries, anterolateral central arteries, or antero-lateral ganglionic branches are a group of small arteries arising from the initial part M1 of the middle cerebral artery that supply the basal ganglia. Structure The lenticul ...

, which branch from the

. It is also supplied by anterior choroidal artery. Small branches from these create holes, which give the anterior perforated substance its name.

History

The anterior perforated substance is named after the holes created by small

blood vessels Blood vessels are the structures of the circulatory system that transport blood throughout the human body. These vessels transport blood cells, nutrients, and oxygen to the tissues of the body. They also take waste and carbon dioxide away fro ...

that supply it.

Additional images

File:Human brainstem anterior view 2 description.JPG, Human brainstem anterior view File:Slide2ZEB.JPG, Cerebrum. Inferior view.Deep dissection

References

External links

* - "

Interpeduncular fossa The interpeduncular fossa is a deep depression of the ventral surface of the midbrain between the two crura cerebri. It has been found in humans and macaques, but not in rats or mice, showing that this is a relatively new evolutionary region. A ...

" (#6)
Photo at umdnj.edu

NIF Search - Anterior perforated substance
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Neuroscience Information Framework The Neuroscience Information Framework is a repository of global neuroscience web resources, including experimental, clinical, and translational neuroscience databases, knowledge bases, atlases, and genetic/ genomic resources and provides many aut ...