Alexander Ellinger (17 April 1870 in

Frankfurt am Main Frankfurt am Main () is the most populous city in the States of Germany, German state of Hesse. Its 773,068 inhabitants as of 2022 make it the List of cities in Germany by population, fifth-most populous city in Germany. Located in the forela ...

– 26 July 1923 in Frankfurt am Main) was a German chemist and

pharmacologist Pharmacology is the science of drugs and medications, including a substance's origin, composition, pharmacokinetics, pharmacodynamics, therapeutic use, and toxicology. More specifically, it is the study of the interactions that occur between ...

. From 1887 he studied chemistry at the

University of Berlin The Humboldt University of Berlin (, abbreviated HU Berlin) is a public research university in the central borough of Mitte in Berlin, Germany. The university was established by Frederick William III on the initiative of Wilhelm von Humbol ...

under

August Wilhelm von Hofmann August Wilhelm von Hofmann (8 April 18185 May 1892) was a German chemist who made considerable contributions to organic chemistry. His research on aniline helped lay the basis of the aniline-dye industry, and his research on coal tar laid the g ...

and at the

University of Bonn The University of Bonn, officially the Rhenish Friedrich Wilhelm University of Bonn (), is a public research university in Bonn, North Rhine-Westphalia, Germany. It was founded in its present form as the () on 18 October 1818 by Frederick Willi ...

as a pupil of

August Kekulé Friedrich August Kekulé, later Friedrich August Kekule von Stradonitz ( , ; 7 September 1829 – 13 July 1896), was a German organic chemist. From the 1850s until his death, Kekulé was one of the most prominent chemists in Europe, especially ...

. Afterwards, he studied medicine at the

University of Munich The Ludwig Maximilian University of Munich (simply University of Munich, LMU or LMU Munich; ) is a public university, public research university in Munich, Bavaria, Germany. Originally established as the University of Ingolstadt in 1472 by Duke ...

, followed by work as an assistant in the institute of pharmacology at the

University of Strasbourg The University of Strasbourg (, Unistra) is a public research university located in Strasbourg, France, with over 52,000 students and 3,300 researchers. Founded in the 16th century by Johannes Sturm, it was a center of intellectual life during ...

. In 1897 he became an assistant to Max Jaffé in the laboratory of

medicinal chemistry Medicinal or pharmaceutical chemistry is a scientific discipline at the intersection of chemistry and pharmacy involved with drug design, designing and developing pharmaceutical medication, drugs. Medicinal chemistry involves the identification, ...

and experimental pharmacology at the

University of Königsberg The University of Königsberg () was the university of Königsberg in Duchy of Prussia, which was a fief of Poland. It was founded in 1544 as the world's second Protestant Reformation, Protestant academy (after the University of Marburg) by Duke A ...

. In 1914 he was appointed professor of pharmacology at the newly established University of Frankfurt.Ellinger, Alexander
In:

Neue Deutsche Biographie (''NDB''; Literal translation, literally ''New German Biography'') is a Biography, biographical reference work. It is the successor to the ''Allgemeine Deutsche Biographie'' (ADB, Universal German Biography). The 27 volumes published thus far co ...

4 (1959), S. 457 f. He is remembered for his extensive biochemical research of several

amino acids Amino acids are organic compounds that contain both amino and carboxylic acid functional groups. Although over 500 amino acids exist in nature, by far the most important are the Proteinogenic amino acid, 22 α-amino acids incorporated into p ...

, especially

tryptophan Tryptophan (symbol Trp or W) is an α-amino acid that is used in the biosynthesis of proteins. Tryptophan contains an α-amino group, an α-carboxylic acid group, and a side chain indole, making it a polar molecule with a non-polar aromat ...

. In 1904 he isolated

kynurenic acid Kynurenic acid (KYNA or KYN) is a product of the normal metabolism of amino acid -tryptophan. It has been shown that kynurenic acid possesses neuroactive activity. It acts as an antiexcitotoxic and anticonvulsant, most likely through acting as an ...

from the urine of dogs that had been fed tryptophan. His other work included studies on the water exchange between

body tissue In biology, tissue is an assembly of similar cells and their extracellular matrix from the same embryonic origin that together carry out a specific function. Tissues occupy a biological organizational level between cells and a complete org ...

s and blood, on the formation on

lymph Lymph () is the fluid that flows through the lymphatic system, a system composed of lymph vessels (channels) and intervening lymph nodes whose function, like the venous system, is to return fluid from the tissues to be recirculated. At the ori ...

, and with chemist Karl Spiro, he conducted investigations of

blood coagulation Coagulation, also known as clotting, is the process by which blood changes from a liquid to a gel, forming a blood clot. It results in hemostasis, the cessation of blood loss from a damaged vessel, followed by repair. The process of coagulatio ...

.Journal of the Chemical Society, Volume 72, Issue 2, Part 1
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Partial bibliography

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References

{{DEFAULTSORT:Ellinger, Alexander 1870 births 1923 deaths Scientists from Frankfurt Academic staff of the University of Königsberg Academic staff of Goethe University Frankfurt University of Bonn alumni Humboldt University of Berlin alumni Ludwig Maximilian University of Munich alumni German pharmacologists 20th-century German chemists