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Max Jaffé
The Jaffe reaction is a colorimetric method used in clinical chemistry to determine creatinine levels in blood and urine. In 1886, Max Jaffe (1841–1911) wrote about its basic principles in the paper ''Über den Niederschlag, welchen Pikrinsäure in normalem Harn erzeugt und über eine neue Reaction des Kreatinins'' in which he described the properties of creatinine and picric acid in an alkaline solution. The color change that occurred was directly proportional to the concentration of creatinine, however he also noted that several other organic compounds induced similar reactions. In the early 20th century, Otto Folin adapted Jaffe's research into a clinical procedure. The Jaffe reaction, despite its nonspecificity for creatinine, is still widely employed as the method of choice for creatinine testing due to its speed, adaptability in automated analysis, and cost-effectiveness, and is the oldest methodology continued to be used in the medical laboratory. It is this nonspecific ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Grünberg In Schlesien
Grünberg or Gruenberg (German for ''green mountain'') may refer to: Places * Grünberg, Hesse, a town in Hesse * Grünberg (St. Bernhard-Frauenhofen), a part of Sankt Bernhard-Frauenhofen, Austria * Grünberg, the German name for Zielona Góra, Poland * Grünberg, a part of Leopoldshagen, Mecklenburg, Western Pomerania * Grünberg, a part of Ottendorf-Okrilla, Saxony * Gruenberg, South Australia is now part of Moculta, east of the Barossa Valley Other uses * Grünberg (surname) * Grünberg aerial tramway, in Gmunden, Austria See also * Greenberg * Grinberg Grinberg is a surname, a Yiddish variant of Grünberg, literally "green mountain" in German. Notable people with the surname include: *Adam Grinberg, birth name of Adam Greenberg (cinematographer) (born 1939), Polish cinematographer * Alexander G ..., Grynberg * Grünburg {{DEFAULTSORT:Grunberg ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Organic Compound
Some chemical authorities define an organic compound as a chemical compound that contains a carbon–hydrogen or carbon–carbon bond; others consider an organic compound to be any chemical compound that contains carbon. For example, carbon-containing compounds such as alkanes (e.g. methane ) and its derivatives are universally considered organic, but many others are sometimes considered inorganic, such as certain compounds of carbon with nitrogen and oxygen (e.g. cyanide ion , hydrogen cyanide , chloroformic acid , carbon dioxide , and carbonate ion ). Due to carbon's ability to catenate (form chains with other carbon atoms), millions of organic compounds are known. The study of the properties, reactions, and syntheses of organic compounds comprise the discipline known as organic chemistry. For historical reasons, a few classes of carbon-containing compounds (e.g., carbonate salts and cyanide salts), along with a few other exceptions (e.g., carbon dioxide, and even ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sputum
Sputum is mucus that is coughed up from the lower airways (the trachea and bronchi). In medicine, sputum samples are usually used for a naked-eye examination, microbiological investigation of respiratory infections, and Cytopathology, cytological investigations of respiratory system. A naked eye exam of the sputum can be done at home by a patient in order to note the various colors (see below). Any hint of yellow or green color (pus) suggests an airway infection (but does not indicate the type of organism causing it). Such color hints are best detected when the sputum is viewed against a bright white background, such as white paper, a white pot, or a white sink surface. Having green, yellow, or thickened phlegm (sputum) does not always indicate the presence of an infection. Also, if an infection is present, the color of the phlegm (sputum) does not determine whether a virus, a bacterium or another pathogen has caused it. Simple allergies can also cause changes in the color of mu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Königsberg
Königsberg (; ; ; ; ; ; , ) is the historic Germany, German and Prussian name of the city now called Kaliningrad, Russia. The city was founded in 1255 on the site of the small Old Prussians, Old Prussian settlement ''Twangste'' by the Teutonic Knights during the Northern Crusades, Baltic Crusades. It was named in honour of King Ottokar II of Bohemia, who led a campaign against the pagan Old Prussians, a Baltic tribe. A Baltic Sea, Baltic port city, it successively became the capital of the State of the Teutonic Order, the Duchy of Prussia and the provinces of East Prussia and Province of Prussia, Prussia. Königsberg remained the coronation city of the Prussian monarchy from 1701 onwards, though the capital was Berlin. From the thirteenth to the twentieth centuries on, the inhabitants spoke predominantly German language, German, although the city also had a profound influence upon the Lithuanian and Polish cultures. It was a publishing center of Lutheranism, Lutheran literatu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wilhelm Kühne
Wilhelm Friedrich Kühne (28 March 183710 June 1900) was a German physiologist. He coined the word enzyme in 1878. Biography Kühne was born at Hamburg on 28 March 1837. After attending the gymnasium in Lüneburg, he went to Göttingen, where his master in chemistry was Friedrich Wöhler and in physiology Rudolph Wagner. Having graduated in 1856, he studied under various famous physiologists, including Emil du Bois-Reymond at Berlin, Claude Bernard in Paris, and KFW Ludwig and EW von Brücke in Vienna. At the end of 1863 he was put in charge of the chemical department of the pathological laboratory at Berlin, under Rudolf Virchow; in 1868 he was appointed professor of physiology at Amsterdam; and in 1871 he was chosen to succeed Hermann von Helmholtz in the same capacity at Heidelberg, where he died on 10 June 1900. Works Kühne's original work falls into two main groups, the physiology of muscle, and nerve, which occupied the earlier years of his life. In 1864 Kühne ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ludwig Traube (physician)
Ludwig Traube (12 January 1818 in Racibórz, Ratibor, Silesia Province, Silesia, now Racibórz, Poland – 11 April 1876 in Berlin) was a German physician and co-founder of the experimental pathology in Germany. Biography Ludwig Traube was a son of a Jewish wine merchant. In 1835, at age 17, he left the gymnasium in Ratibor. He studied medicine in Breslau, Berlin and Vienna. Among his teachers were Jan Evangelista Purkyně (1787–1869) and Johannes Peter Müller, Johannes Müller (1801–1858). Besides medicine, he was very active in philosophical studies; he especially appreciated the philosophy of Spinoza. In 1840 he received his doctorate („Specimina nonnulla physiologica et pathologica“), a work about pulmonary emphysema. Then he moved to Vienna to broaden his knowledge (Baron Carl von Rokitansky (1804–1878) und Joseph Škoda (1805–1881). Since 1841 he was assistant of a physician for paupers in Berlin. In 1848 he became an unsalaried lecturer and in 1849 the first civ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Poland
Poland, officially the Republic of Poland, is a country in Central Europe. It extends from the Baltic Sea in the north to the Sudetes and Carpathian Mountains in the south, bordered by Lithuania and Russia to the northeast, Belarus and Ukraine to the east, Slovakia and the Czech Republic to the south, and Germany to the west. The territory has a varied landscape, diverse ecosystems, and a temperate climate. Poland is composed of Voivodeships of Poland, sixteen voivodeships and is the fifth most populous member state of the European Union (EU), with over 38 million people, and the List of European countries by area, fifth largest EU country by area, covering . The capital and List of cities and towns in Poland, largest city is Warsaw; other major cities include Kraków, Wrocław, Łódź, Poznań, and Gdańsk. Prehistory and protohistory of Poland, Prehistoric human activity on Polish soil dates to the Lower Paleolithic, with continuous settlement since the end of the Last Gla ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Zielona Góra
Zielona Góra (; ''Green Mountain''; ) is the largest city in Lubusz Voivodeship, located in western Poland, with 140,403 inhabitants (). The region is closely associated with vineyards and holds an annual Zielona Góra Wine Fest, Wine Fest. Zielona Góra is one of the two capital cities of Lubusz Voivodeship, hosting the Voivodeship sejmik, province's elected assembly, while the seat of the centrally appointed voivode, governor is in the city of Gorzów Wielkopolski. In 1222 Duke Henry the Bearded from the Piast dynasty brought the first settlers to the area. In 1323 Zielona Góra was granted town privileges. The town was incorporated into the Kingdom of Bohemia in 1506 and became part of the Habsburg monarchy, Habsburg Empire in 1526. It experienced a wave of witch trials in the 17th century. As a result of the First Silesian War, the city became part of the Kingdom of Prussia in 1742. It then was part of the North German Confederation and the German Reich until the end of Worl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmacologist
Pharmacology is the science of drugs and medications, including a substance's origin, composition, pharmacokinetics, pharmacodynamics, therapeutic use, and toxicology. More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. If substances have medicinal properties, they are considered pharmaceuticals. The field encompasses drug composition and properties, functions, sources, synthesis and drug design, molecular and cellular mechanisms, organ/systems mechanisms, signal transduction/cellular communication, molecular diagnostics, interactions, chemical biology, therapy, and medical applications and antipathogenic capabilities. The two main areas of pharmacology are pharmacodynamics and pharmacokinetics. Pharmacodynamics studies the effects of a drug on biological systems, and pharmacokinetics studies the effects of biological systems on a drug. In broad terms, pharmacodynamics ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pathologist
Pathology is the study of disease. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in the context of modern medical treatment, the term is often used in a narrower fashion to refer to processes and tests that fall within the contemporary medical field of "general pathology", an area that includes a number of distinct but inter-related medical specialties that diagnose disease, mostly through analysis of tissue and human cell samples. Idiomatically, "a pathology" may also refer to the predicted or actual progression of particular diseases (as in the statement "the many different forms of cancer have diverse pathologies", in which case a more proper choice of word would be " pathophysiologies"). The suffix ''pathy'' is sometimes used to indicate a state of disease in cases of both physical ailment (as in cardiomyopathy) and psychological conditions (such as ps ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biochemist
Biochemists are scientists who are trained in biochemistry. They study chemical processes and chemical transformations in living organisms. Biochemists study DNA, proteins and Cell (biology), cell parts. The word "biochemist" is a portmanteau of "biological chemist." Biochemists also research how certain chemical reactions happen in cells and Tissue (biology), tissues and observe and record the effects of Product (chemistry), products in food additives and Medication, medicines. Biochemist researchers focus on playing and constructing research experiments, mainly for developing new products, updating existing products and analyzing said products. It is also the responsibility of a biochemist to present their research findings and create Grant writing, grant proposals to obtain Funding of science, funds for future research. Biochemists study aspects of the immune system, the expressions of genes, isolating, analyzing, and synthesizing different products, mutations that lead to ca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jaffe Reaction
The Jaffe reaction is a colorimetric method used in clinical chemistry to determine creatinine levels in blood and urine. In 1886, Max Jaffe (1841–1911) wrote about its basic principles in the paper ''Über den Niederschlag, welchen Pikrinsäure in normalem Harn erzeugt und über eine neue Reaction des Kreatinins'' in which he described the properties of creatinine and picric acid in an alkaline solution. The color change that occurred was directly proportional to the concentration of creatinine, however he also noted that several other organic compounds induced similar reactions. In the early 20th century, Otto Folin adapted Jaffe's research into a clinical procedure. The Jaffe reaction, despite its nonspecificity for creatinine, is still widely employed as the method of choice for creatinine testing due to its speed, adaptability in automated analysis, and cost-effectiveness, and is the oldest methodology continued to be used in the medical laboratory. It is this nonspecifici ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
