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Agostino Bassi, sometimes called de Lodi (25 September 1773 – 8 February 1856), was an Italian
entomologist Entomology (from Ancient Greek ἔντομον (''éntomon''), meaning "insect", and -logy from λόγος (''lógos''), meaning "study") is the branch of zoology that focuses on insects. Those who study entomology are known as entomologists. In ...
. He preceded
Louis Pasteur Louis Pasteur (, ; 27 December 1822 – 28 September 1895) was a French chemist, pharmacist, and microbiologist renowned for his discoveries of the principles of vaccination, Fermentation, microbial fermentation, and pasteurization, the la ...
in the discovery that microorganisms can be the cause of disease (the
germ theory of disease The germ theory of disease is the currently accepted scientific theory for many diseases. It states that microorganisms known as pathogens or "germs" can cause disease. These small organisms, which are too small to be seen without magnification, ...
). He discovered that the muscardine disease of silkworms was caused by a living, very small, parasitic organism, a
fungus A fungus (: fungi , , , or ; or funguses) is any member of the group of eukaryotic organisms that includes microorganisms such as yeasts and mold (fungus), molds, as well as the more familiar mushrooms. These organisms are classified as one ...
that would be named eventually '' Beauveria bassiana'' in his honor. In 1844, he stated the idea that not only animal (insect), but also human diseases are caused by other living microorganisms; for example,
measles Measles (probably from Middle Dutch or Middle High German ''masel(e)'', meaning "blemish, blood blister") is a highly contagious, Vaccine-preventable diseases, vaccine-preventable infectious disease caused by Measles morbillivirus, measles v ...
,
syphilis Syphilis () is a sexually transmitted infection caused by the bacterium ''Treponema pallidum'' subspecies ''pallidum''. The signs and symptoms depend on the stage it presents: primary, secondary, latent syphilis, latent or tertiary. The prim ...
, and the plague.


Early life

He was the son of a wealthy farmer and a lawyer who also had a passion for biology. However, his father did not want him to take up biology, but wanted him instead to look after the family's property, to become a civil servant and to join the Imperial administration. Bassi did so, but also followed the lessons of Lazzaro Spallanzani, a relative, until he died.


Career

His studies of 1807 concerned ''mal de segno'' (also known as muscardine, after a French candy), a lethal disease of domestic silkworms (''Bombyx mori''). Infected caterpillars are covered with a fine white powder and die. This disease initially appeared in Italy around 1805; then in France, by 1841. After 1849, the
silk Silk is a natural fiber, natural protein fiber, some forms of which can be weaving, woven into textiles. The protein fiber of silk is composed mainly of fibroin and is most commonly produced by certain insect larvae to form cocoon (silk), c ...
farms were almost all abandoned because of this devastating disease. Giacomo Maria Foscarini had proved that muscardine was contagious. The research to find the cause of the disease took Bassi 25 years. He published the results of his investigations in a paper entitled ''Del mal del segno, calcinaccio o moscardino'' (1835), stating that a living entity was the culprit, and that it was contagious; we now know that the powdery appearance on the killed silkworms is caused by the production of millions of infectious white fungal spores on the dead insect (see '' Beauveria bassiana''). He is credited with rescuing the economically important
silk Silk is a natural fiber, natural protein fiber, some forms of which can be weaving, woven into textiles. The protein fiber of silk is composed mainly of fibroin and is most commonly produced by certain insect larvae to form cocoon (silk), c ...
industry, by recommendations like the use of disinfectants; separating the rows of feeding caterpillars; isolating and destroying infected caterpillars; and keeping the farms clean. This brought Bassi immediate fame. "''Del Mal del Segno, Calcinaccio o Moscardino''" was translated into French and distributed throughout Europe. From this work he expanded on a theory explaining that many
disease A disease is a particular abnormal condition that adversely affects the structure or function (biology), function of all or part of an organism and is not immediately due to any external injury. Diseases are often known to be medical condi ...
s of
plants Plants are the eukaryotes that form the kingdom Plantae; they are predominantly photosynthetic. This means that they obtain their energy from sunlight, using chloroplasts derived from endosymbiosis with cyanobacteria to produce sugars f ...
, animals and human beings were caused by pathogenic organisms. He thus preceded the work of
Louis Pasteur Louis Pasteur (, ; 27 December 1822 – 28 September 1895) was a French chemist, pharmacist, and microbiologist renowned for his discoveries of the principles of vaccination, Fermentation, microbial fermentation, and pasteurization, the la ...
and Robert Koch. He was also the author of work on the culture of potatoes, on cheese, wine making,
leprosy Leprosy, also known as Hansen's disease (HD), is a Chronic condition, long-term infection by the bacteria ''Mycobacterium leprae'' or ''Mycobacterium lepromatosis''. Infection can lead to damage of the Peripheral nervous system, nerves, respir ...
and
cholera Cholera () is an infection of the small intestine by some Strain (biology), strains of the Bacteria, bacterium ''Vibrio cholerae''. Symptoms may range from none, to mild, to severe. The classic symptom is large amounts of watery diarrhea last ...
. Louis Pasteur (1822–1895) was greatly influenced by his work. Pasteur had the portraits of both Spallanzani and Bassi in his office.


Bassi’s tomb in Lodi

Agostino Bassi was buried in the Romanesque church of Saint Francis (13th century). His tomb can be seen in the right
transept A transept (with two semitransepts) is a transverse part of any building, which lies across the main body of the building. In cruciform ("cross-shaped") cruciform plan, churches, in particular within the Romanesque architecture, Romanesque a ...
, laid to a wall, at the ground level.


Philately

In 1953 the Italian post office issued a stamp on the 180th anniversary of Bassi's birth in 1773. The stamp features a portrait of Bassi bordered by silkmoth adults and pupa


References

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External links

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Some places and memories related to Agostino Bassi
{{DEFAULTSORT:Bassi, Agostino Italian entomologists Italian Roman Catholics 1773 births 1856 deaths