The adiponectin receptors (AdipoRs) include the following two
receptors, which are bound and activated by
adiponectin
Adiponectin (also referred to as GBP-28, apM1, AdipoQ and Acrp30) is a protein hormone and adipokine, which is involved in regulating glucose levels as well as fatty acid breakdown. In humans it is encoded by the ''ADIPOQ'' gene and it is produce ...
:
*
Adiponectin receptor 1
Adiponectin receptor 1 (AdipoR1) is a protein which in humans is encoded by the ''ADIPOR1'' gene. It is a member of the progestin and adipoQ receptor (PAQR) family, and is also known as PAQR1.
Structure
Similar to G protein-coupled receptors (GP ...
(AdipoR1, PAQR1)
*
Adiponectin receptor 2
Adiponectin receptor 2 (AdipoR2) is a protein which in humans is encoded by the ''ADIPOR2'' gene. It is a member of the progestin and adipoQ receptor (PAQR) family, and is also known as PAQR2.
Structure
Similar to G protein-coupled receptors (GPC ...
(AdipoR2, PAQR2)
They are members of the
progestin and adipoQ receptor
The progestin and adipoQ receptor (PAQR) family is a group of receptors related to but distinct from the G protein-coupled receptor family, which have the similar seven transmembrane structure, but the N-terminal is located on the inner side of th ...
(PAQR) family.
In 2016, the University of Tokyo announced that it would launch an investigation into claims of fabrication of AdipoR1 and AdipoR2 identification data, as accused by an anonymous person/group called
Ordinary_researchers.
[University of Tokyo to investigate data manipulation charges against six prominent research groups](_blank)
ScienceInsider, Dennis Normile, Sep 20, 2016
References
Receptors
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