QJ51A
Tetracyclines
Tetracyclines are a group of broad-spectrum antibiotic compounds that have a common basic structure and are either isolated directly from several species of ''Streptomyces'' bacteria or produced semi-synthetically from those isolated compounds. T ...
for intramammary use
QJ51AA Tetracyclines
:QJ51AA03
Chlortetracycline
Chlortetracycline (trade name Aureomycin, Lederle Laboratories) is a tetracycline antibiotic, the first tetracycline to be identified. It was discovered in 1945 at Lederle Laboratories under the supervision of scientist Yellapragada Subbarow and ...
:QJ51AA06
Oxytetracycline
Oxytetracycline is a broad-spectrum tetracycline antibiotic, the second of the group to be discovered.
Oxytetracycline works by interfering with the ability of bacteria to produce essential proteins. Without these proteins, the bacteria cannot g ...
:QJ51AA07
Tetracycline
Tetracycline, sold under various brand names, is an oral antibiotic in the tetracyclines family of medications, used to treat a number of infections, including acne, cholera, brucellosis, plague, malaria, and syphilis.
Common side effects ...
:QJ51AA53
Chlortetracycline
Chlortetracycline (trade name Aureomycin, Lederle Laboratories) is a tetracycline antibiotic, the first tetracycline to be identified. It was discovered in 1945 at Lederle Laboratories under the supervision of scientist Yellapragada Subbarow and ...
, combinations
QJ51B
Amphenicol
Amphenicols are a class of antibiotics with a phenylpropanoid structure. They function by blocking the enzyme peptidyl transferase on the 50S ribosome subunit of bacteria.
Examples of amphenicols include chloramphenicol, thiamphenicol, azidamf ...
s for intramammary use
QJ51BA Amphenicols
:QJ51BA01
Chloramphenicol
Chloramphenicol is an antibiotic
An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting pathogenic bacteria, bacterial infections, and antibiotic medica ...
:QJ51BA02
Thiamphenicol
Thiamphenicol (also known as thiophenicol and dextrosulphenidol) is an antibiotic. It is the methyl-sulfonyl analogue of chloramphenicol and has a similar spectrum of activity, but is 2.5 to 5 times as potent. Like chloramphenicol, it is insolub ...
:QJ51BA90
Florfenicol
Florfenicol (marketed by Schering-Plough Animal Health under the trade name Nuflor) is a fluorinated synthetic analog of thiamphenicol, mainly used in veterinary medicine.
As a generic, it is now available worldwide.
Indications
In the United ...
QJ51C
Beta-lactam
A beta-lactam (β-lactam) ring is a four-membered lactam. A ''lactam'' is a cyclic amide, and ''beta''-lactams are named so because the nitrogen atom is attached to the β-carbon atom relative to the carbonyl. The simplest β-lactam possible i ...
antibacterials,
penicillins
Penicillins (P, PCN or PEN) are a group of β-lactam antibiotics originally obtained from ''Penicillium'' moulds, principally ''P. chrysogenum'' and '' P. rubens''. Most penicillins in clinical use are synthesised by P. chrysogenum using d ...
, for intramammary use
QJ51CA Penicillins with extended spectrum
:QJ51CA01
Ampicillin
Ampicillin is an antibiotic used to prevent and treat a number of bacterial infections, such as respiratory tract infections, urinary tract infections, meningitis, salmonellosis, and endocarditis. It may also be used to prevent group B stre ...
:QJ51CA51 Ampicillin, combinations
QJ51CE Beta-lactamase sensitive penicillins
:QJ51CE01
Benzylpenicillin
Benzylpenicillin, also known as penicillin G (PenG) or BENPEN, and in military slang "Peanut Butter Shot" is an antibiotic used to treat a number of bacterial infections. This includes pneumonia, strep throat, syphilis, necrotizing enterocoli ...
:QJ51CE09
Procaine penicillin
Procaine benzylpenicillin also known as penicillin G procaine, is an antibiotic useful for the treatment of a number of bacterial infections. Specifically it is used for syphilis, anthrax, mouth infections, pneumonia, diphtheria, cellulitis, and a ...
:QJ51CE59 Procaine penicillin, combinations
:QJ51CE90
Phenetamate
QJ51CF Beta-lactamase resistant penicillins
:QJ51CF01
Dicloxacillin
Dicloxacillin is a narrow-spectrum β-lactam antibiotic of the penicillin class. It is used to treat infections caused by susceptible (non-resistant) Gram-positive bacteria.Product Information: DICLOXACILLIN SODIUM-dicloxacillin sodium capsule. ...
:QJ51CF02
Cloxacillin
Cloxacillin is an antibiotic useful for the treatment of a number of bacterial infections. This includes impetigo, cellulitis, pneumonia, septic arthritis, and otitis externa. It is not effective for methicillin-resistant ''Staphylococcus aureu ...
:QJ51CF03
Meticillin
Methicillin ( USAN), also known as meticillin (INN), is a narrow-spectrum β-lactam antibiotic of the penicillin class.
Methicillin was discovered in 1960.
Medical uses
Compared to other penicillins that face antimicrobial resistance du ...
:QJ51CF04
Oxacillin
Oxacillin (trade name Bactocill) is a narrow-spectrum antibiotic, narrow-spectrum beta-lactam antibiotic of the penicillin class developed by Beecham (pharmaceutical company), Beecham.
It was patented in 1960 and approved for medical use in 1962 ...
:QJ51CF05
Flucloxacillin
Flucloxacillin, also known as floxacillin, is an antibiotic used to treat skin infections, external ear infections, infections of leg ulcers, diabetic foot infections, and infection of bone. It may be used together with other medications to t ...
QJ51CR Combinations of pencillins and/or beta-lactamase inhibitors
:QJ51CR01 Ampicillin and enzyme inhibitor
:QJ51CR02
Amoxicillin
Amoxicillin is an antibiotic medication used to treat a number of bacterial infections. These include middle ear infection, strep throat, pneumonia, skin infections, and urinary tract infections among others. It is taken by mouth, or less comm ...
and enzyme inhibitor
:QJ51CR50 Combinations of penicillins
QJ51D Other beta-lactam antibacterials for intramammary use
QJ51DB First-generation
cephalosporin
The cephalosporins (sg. ) are a class of β-lactam antibiotics originally derived from the fungus '' Acremonium'', which was previously known as ''Cephalosporium''.
Together with cephamycins, they constitute a subgroup of β-lactam antibioti ...
s
:QJ51DB01
Cefalexin
Cefalexin, also spelled cephalexin, is an antibiotic that can treat a number of bacterial infections. It kills gram-positive and some gram-negative bacteria by disrupting the growth of the bacterial cell wall. Cefalexin is a beta-lactam ant ...
:QJ51DB04
Cefazolin
Cefazolin, also known as cefazoline and cephazolin, is a first-generation cephalosporin antibiotic used for the treatment of a number of bacterial infections. Specifically it is used to treat cellulitis, urinary tract infections, pneumonia, endo ...
:QJ51DB08
Cefapirin
Cefapirin (INN, also spelled cephapirin) is an injectable, first-generation cephalosporin antibiotic. It is marketed under the trade name Cefadyl. Production for use in humans has been discontinued in the United States.
It also has a role in vete ...
:QJ51DB10
Cefacetrile
Cefacetrile (INN, also spelled cephacetrile) is a broad-spectrum first generation cephalosporin antibiotic effective in gram-positive and gram-negative bacterial infections. It is a bacteriostatic antibiotic. Cefacetrile is marketed under the t ...
:QJ51DB90
Cefalonium
Cefalonium (INN) is a first-generation cephalosporin
The cephalosporins (sg. ) are a class of β-lactam antibiotics originally derived from the fungus ''Acremonium'', which was previously known as ''Cephalosporium''.
Together with cephamyci ...
QJ51DC Second-generation cephalosporins
:QJ51DC02
Cefuroxime
Cefuroxime, sold under the brand name Zinacef among others, is a second-generation cephalosporin antibiotic used to treat and prevent a number of bacterial infections. These include pneumonia, meningitis, otitis media, sepsis, urinary tract inf ...
QJ51DD Third-generation cephalosporins
:QJ51DD12
Cefoperazone
Cefoperazone is a third-generation cephalosporin antibiotic, marketed by Pfizer under the name Cefobid. It is one of few cephalosporin antibiotics effective in treating '' Pseudomonas'' bacterial infections which are otherwise resistant to these ...
:QJ51DD90
Ceftiofur
Ceftiofur is an antibiotic of the cephalosporin type ( third generation), licensed for use in veterinary medicine. It was first described in 1987. It is marketed by pharmaceutical company Zoetis as Excenel, Naxcel, and Excede and is also the activ ...
QJ51DE Fourth-generation cephalosporins
:QJ51DE90
Cefquinome
Cefquinome is a fourth-generation cephalosporin with pharmacological and antibacterial properties valuable in the treatment of coliform mastitis and other infections. It is only used in veterinary applications.
Properties
Cefquinome is resist ...
QJ51E
sulfonamide
In organic chemistry, the sulfonamide functional group (also spelled sulphonamide) is an organosulfur group with the structure . It consists of a sulfonyl group () connected to an amine group (). Relatively speaking this group is unreactiv ...
s and
trimethoprim
Trimethoprim (TMP) is an antibiotic used mainly in the treatment of bladder infections. Other uses include for middle ear infections and travelers' diarrhea. With sulfamethoxazole or dapsone it may be used for ''Pneumocystis'' pneumonia in pe ...
for intramammary use
QJ51EA Trimethoprim and derivatives
:QJ51EA01 Trimethoprim
QJ51F
Macrolide
The Macrolides are a class of natural products that consist of a large macrocyclic lactone ring to which one or more deoxy sugars, usually cladinose and desosamine, may be attached. The lactone rings are usually 14-, 15-, or 16-membered. M ...
s and
lincosamide
Lincosamides are a class of antibiotics, which include lincomycin, clindamycin, and pirlimycin.
Structure
Lincosamides consist of a pyrrolidine ring linked to a pyranose moiety (methylthio-lincosamide) via an amide bond. Hydrolysis of lincosami ...
s for intramammary use
QJ51FA Macrolides
:QJ51FA01
Erythromycin
Erythromycin is an antibiotic used for the treatment of a number of bacterial infections. This includes respiratory tract infections, skin infections, chlamydia infections, pelvic inflammatory disease, and syphilis. It may also be used du ...
:QJ51FA02
Spiramycin
Spiramycin is a macrolide
The Macrolides are a class of natural products that consist of a large macrocyclic lactone ring to which one or more deoxy sugars, usually cladinose and desosamine, may be attached. The lactone rings are usuall ...
:QJ51FA90
Tylosin
Tylosin is a macrolide antibiotic and bacteriostatic feed additive used in veterinary medicine. It has a broad spectrum of activity against Gram-positive organisms and a limited range of Gram-negative organisms. It is found naturally as a ferme ...
QJ51FF Lincosamides
:QJ51FF90
Pirlimycin
Pirlimycin hydrochloride belongs to the lincosamide class of antimicrobials. Under the trade name Pirsue, it is used in the treatment of mastitis in cattle.
Activity
Pirlimycin is active against Gram-positive bacteria, specifically ''Staphylo ...
:QJ51FF02
Lincomycin
Lincomycin is a lincosamide antibiotic that comes from the actinomycete ''Streptomyces lincolnensis''. A related compound, clindamycin, is derived from lincomycin by using thionyl chloride to replace the 7-hydroxy group with a chlorine atom wit ...
QJ51G
Aminoglycoside
Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside ( sugar). The term can also refer ...
antibacterials for intramammary use
QJ51GA
Streptomycin
Streptomycin is an antibiotic medication used to treat a number of bacterial infections, including tuberculosis, ''Mycobacterium avium'' complex, endocarditis, brucellosis, ''Burkholderia'' infection, plague, tularemia, and rat bite fever ...
s
:QJ51GA90
Dihydrostreptomycin
Dihydrostreptomycin is a derivative of streptomycin that has a bactericidal properties. It is a semisynthetic aminoglycoside antibiotic used in the treatment of tuberculosis.
It acts by irreversibly binding the S12 protein in the bacterial 30S r ...
QJ51GB Other aminoglycosides
:QJ51GB03
Gentamicin
Gentamicin is an antibiotic used to treat several types of bacterial infections. This may include bone infections, endocarditis, pelvic inflammatory disease, meningitis, pneumonia, urinary tract infections, and sepsis among others. It is not ...
:QJ51GB90
Apramycin
Apramycin (also ''Nebramycin II'') is an aminoglycoside antibiotic
An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and anti ...
QJ51R Combination of antibacterials for intramammary use
QJ51RA Tetracyclines, combinations with other antibacterials
:QJ51RA01 Chlortetracycline, combinations with other antibacterials
QJ51RB Amphenicols, combinations with other antibacterials
:QJ51RB01 Chloramphenicol, combinations with other antibacterials
QJ51RC Beta-lactam antibacterials, penicillins, combinations with other antibacterials
:QJ51RC04 Procaine penicillin, dihydrostreptomycin, sulfadimidin
:QJ51RC20 Ampicillin, combinations with other antibacterials
:QJ51RC21
Pivampicillin
Pivampicillin is a pivaloyloxymethyl ester of ampicillin. It is a prodrug, which is thought to enhance the oral bioavailability of ampicillin because of its greater lipophilicity compared to that of ampicillin.
Adverse effects
Prodrugs that re ...
, combinations with other antibacterials
:QJ51RC22
Benzylpenicillin
Benzylpenicillin, also known as penicillin G (PenG) or BENPEN, and in military slang "Peanut Butter Shot" is an antibiotic used to treat a number of bacterial infections. This includes pneumonia, strep throat, syphilis, necrotizing enterocoli ...
, combinations with other antibacterials
:QJ51RC23 Procaine penicillin, combinations with other antibacterials
:QJ51RC24
Benzathine benzylpenicillin
Benzathine benzylpenicillin, also known as benzathine penicillin G, is an antibiotic medication useful for the treatment of a number of bacterial infections. Specifically it is used to treat strep throat, diphtheria, syphilis, and yaws. It ...
, combinations with other antibacterials
:QJ51RC25
Penethamate hydroiodide, combinations with other antibacterials
:QJ51RC26 Cloxacillin, combinations with other antibacterials
QJ51RD Other beta-lactam antibacterials, combinations with other antibacterials
:QJ51RD01 Cefalexin, combinations with other antibacterials
:QJ51RD34 Cefacetrile, combinations with other antibacterials
QJ51RE Sulfonamides and trimethoprim including derivatives
:QJ51RE01
Sulfadiazine
Sulfadiazine is an antibiotic. Used together with pyrimethamine, a dihydrofolate reductase inhibitor, it is the treatment of choice for toxoplasmosis, which is caused by a protozoan parasite. It is a second-line treatment for otitis media, p ...
and trimethoprim
QJ51RF Macrolides and lincosamides, combinations with other antibacterials
:QJ51RF01 Spiramycin, combinations with other antibacterials
:QJ51RF02 Erythromycin, combinations with other antibacterials
:QJ51RF03
Lincomycin
Lincomycin is a lincosamide antibiotic that comes from the actinomycete ''Streptomyces lincolnensis''. A related compound, clindamycin, is derived from lincomycin by using thionyl chloride to replace the 7-hydroxy group with a chlorine atom wit ...
, combinations with other antibacterials
QJ51RG Aminoglycoside antibacterials, combinations
:QJ51RG01
Neomycin
Neomycin is an aminoglycoside antibiotic that displays bactericidal activity against gram-negative aerobic bacilli and some anaerobic bacilli where resistance has not yet arisen. It is generally not effective against gram-positive bacilli and ...
, combinations with other antibacterials
QJ51RV Combinations of antibacterials and other substances
:QJ51RV01 Antibacterials and
corticosteroid
Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones. Two main classes of corticosteroids, glucocorticoids and mineralocorticoids, are in ...
s
:QJ51RV02 Antibacterials,
antimycotic
An antifungal medication, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis (thrush), serious systemic infections such as cryp ...
s and corticosteroids
QJ51X Other antibacterials for intramammary use
QJ51XB
Polymyxin
Polymyxins are antibiotics. Polymyxins B and E (also known as colistin) are used in the treatment of Gram-negative bacterial infections. They work mostly by breaking up the bacterial cell membrane. They are part of a broader class of molecule ...
s
:QJ51XB01
Colistin
Colistin, also known as polymyxin E, is an antibiotic medication used as a last-resort treatment for multidrug-resistant Gram-negative infections including pneumonia. These may involve bacteria such as ''Pseudomonas aeruginosa'', '' Klebsiella ...
:QJ51XB02
Polymyxin B
Polymyxin B, sold under the brand name Poly-Rx among others, is an antibiotic used to treat meningitis, pneumonia, sepsis, and urinary tract infections. While it is useful for many Gram negative infections, it is not useful for Gram positive infe ...
QJ51XX Other antibacterials for intramammary use
:QJ51XX01
Rifaximin
Rifaximin, is a non-absorbable, broad spectrum antibiotic mainly used to treat travelers' diarrhea. It is based on the rifamycin antibiotics family. Since its approval in Italy in 1987, it has been licensed in over more than 30 countries for th ...
References
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