J04A Drugs for treatment of
tuberculosis
Tuberculosis (TB) is an infectious disease usually caused by ''Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in w ...
J04AA Aminosalicylic acid and derivatives
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Aminosalicylic acid
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Sodium aminosalicylate
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Calcium aminosalicylate
J04AB Antibiotics
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Cycloserine
Cycloserine, sold under the brand name Seromycin, is a GABA transaminase inhibitor and an antibiotic, used to treat tuberculosis. Specifically it is used, along with other antituberculosis medications, for active drug resistant tuberculosis. ...
:J04AB02
Rifampicin
Rifampicin, also known as rifampin, is an ansamycin antibiotic used to treat several types of bacterial infections, including tuberculosis (TB), ''Mycobacterium avium'' complex, leprosy, and Legionnaires’ disease. It is almost always used ...
:J04AB03
Rifamycin
The rifamycins are a group of antibiotics that are synthesized either naturally by the bacterium ''Amycolatopsis rifamycinica'' or artificially. They are a subclass of the larger family of ansamycins. Rifamycins are particularly effective again ...
:J04AB04
Rifabutin
Rifabutin (Rfb) is an antibiotic used to treat tuberculosis and prevent and treat ''Mycobacterium avium'' complex. It is typically only used in those who cannot tolerate rifampin such as people with HIV/AIDS on antiretrovirals. For active tuberc ...
:J04AB05
Rifapentin
Rifapentine, sold under the brand name Priftin, is an antibiotic used in the treatment of tuberculosis. In active tuberculosis it is used together with other antituberculosis medications. In latent tuberculosis it is typically used with isoniazi ...
:J04AB06
Enviomycin
:J04AB30
Capreomycin
Capreomycin is an antibiotic which is given in combination with other antibiotics for the treatment of tuberculosis. Specifically it is a second line treatment used for active drug resistant tuberculosis. It is given by injection into a vein or mu ...
J04AC
Hydrazide Hydrazides in organic chemistry are a class of organic compounds with the formula RNHNH2 where R is acyl (R'CO-), sulfonyl (R'SO2-), or phosphoryl (R'2P(O)-). Unlike hydrazine and alkylhydrazines, hydrazides are nonbasic owing to the inductive infl ...
s
:J04AC01
Isoniazid
Isoniazid, also known as isonicotinic acid hydrazide (INH), is an antibiotic used for the treatment of tuberculosis. For active tuberculosis it is often used together with rifampicin, pyrazinamide, and either streptomycin or ethambutol. For ...
:J04AC51 Isoniazid, combinations
J04AD
Thiocarbamide
Thiourea () is an organosulfur compound with the formula and the structure . It is structurally similar to urea (), except that the oxygen atom is replaced by a sulfur atom (as implied by the ''thio-'' prefix); however, the properties of urea a ...
derivatives
:J04AD01
Protionamide
Protionamide (or prothionamide) is a drug used in the treatment of tuberculosis.
It has also been tested for use in the treatment of leprosy
Leprosy, also known as Hansen's disease (HD), is a long-term infection by the bacteria '' Mycobacte ...
:J04AD02
Tiocarlide
Thiocarlide (or tiocarlide or isoxyl) is a thiourea drug used in the treatment of tuberculosis, inhibiting synthesis of oleic acid and tuberculostearic acid.
Thiocarlide has considerable antimycobacterial activity ''in vitro'' and is effectiv ...
:J04AD03
Ethionamide
Ethionamide is an antibiotic used to treat tuberculosis. Specifically it is used, along with other antituberculosis medications, to treat active multidrug-resistant tuberculosis. It is no longer recommended for leprosy. It is taken by mouth.
Eth ...
J04AK Other drugs for treatment of tuberculosis
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Pyrazinamide
Pyrazinamide is a medication used to treat tuberculosis. For active tuberculosis, it is often used with rifampicin, isoniazid, and either streptomycin or ethambutol. It is not generally recommended for the treatment of latent tuberculosis. It ...
:J04AK02
Ethambutol
Ethambutol (EMB, E) is a medication primarily used to treat tuberculosis. It is usually given in combination with other tuberculosis medications, such as isoniazid, rifampicin and pyrazinamide. It may also be used to treat ''Mycobacterium av ...
:J04AK03
Terizidone
:J04AK04
Morinamide
Morinamide (or morphazinamide, or morinamid) is a drug used in the treatment of tuberculosis. It behaves as a prodrug
A prodrug is a medication or compound that, after intake, is metabolized (i.e., converted within the body) into a pharmacologi ...
:J04AK05
Bedaquiline
Bedaquiline, sold under the brand name Sirturo, is a medication used to treat active tuberculosis. Specifically, it is used to treat multi-drug-resistant tuberculosis (MDR-TB) along with other medications for tuberculosis. It is used by mouth.
...
:J04AK06
Delamanid
:J04AK07
Amithiozone
Thioacetazone (INN, BAN), also known as amithiozone ( USAN), is an oral antibiotic which is used in the treatment of tuberculosis. It has fallen into almost complete disuse due to toxicity and the introduction of improved anti-tuberculosis drugs ...
:J04AK08
Pretomanid
Pretomanid is an antibiotic medication used for the treatment of multi-drug-resistant tuberculosis affecting the lungs. It is generally used together with bedaquiline and linezolid. It is taken by mouth.
The most common side effects include ...
J04AM Combinations of drugs for treatment of tuberculosis
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Streptomycin and isoniazid
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Rifampicin and isoniazid
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Ethambutol and isoniazid
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Thioacetazone and isoniazid
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Rifampicin, pyrazinamide and isoniazid
:J04AM06
Rifampicin, pyrazinamide, ethambutol and isoniazid
:J04AM07
Rifampicin, ethambutol and isoniazid
:J04AM08
Isoniazid, sulfamethoxazole, trimethoprim and pyridoxine
J04B Drugs for treatment of lepra
J04BA Drugs for treatment of lepra
:J04BA01
Clofazimine
Clofazimine, sold under the brand name Lamprene, is a medication used together with rifampicin and dapsone to treat leprosy. It is specifically used for multibacillary (MB) leprosy and erythema nodosum leprosum. Evidence is insufficient to suppo ...
:J04BA02
Dapsone
Dapsone, also known as 4,4'-sulfonyldianiline (SDA) or diaminodiphenyl sulfone (DDS), is an antibiotic commonly used in combination with rifampicin and clofazimine for the treatment of leprosy. It is a second-line medication for the treatment ...
:J04BA03
Aldesulfone sodium
Sulfoxone or aldesulfone sodium is an anti-leprosy drug. It is also known as diasone. Sulfoxone sodium was introduced in Japan in 1948. Ernest Muir introduced it to Western use while serving as superintendent of the Chacachacare Leprosarium on Tri ...
:J04BA50 Dapsone and rifampicin
:J04BA51 Dapsone, rifampicin and clofazimine
References
{{Antimycobacterials
Tuberculosis
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