ATC Code C09
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C09A

ACE inhibitor Angiotensin-converting-enzyme inhibitors (ACE inhibitors) are a class of medication used primarily for the treatment of high blood pressure and heart failure. They work by causing relaxation of blood vessels as well as a decrease in blood volum ...
s, plain


C09AA ACE inhibitors, plain

:C09AA01
Captopril Captopril, sold under the brand name Capoten among others, is an angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and some types of congestive heart failure. Captopril was the first oral ACE inhibitor found ...
:C09AA02
Enalapril Enalapril, sold under the brand name Vasotec among others, is an ACE inhibitor medication used to treat high blood pressure, diabetic kidney disease, and heart failure. For heart failure, it is generally used with a diuretic, such as furosem ...
:C09AA03
Lisinopril Lisinopril is a medication of the angiotensin-converting enzyme (ACE) inhibitor and is used to treat high blood pressure, heart failure, and after heart attacks. For high blood pressure it is usually a first-line treatment. It is also used to ...
:C09AA04
Perindopril Perindopril is a medication used to treat high blood pressure, heart failure, or stable coronary artery disease. As a long-acting ACE inhibitor, it works by relaxing blood vessels and decreasing blood volume. As a prodrug, perindopril is hydro ...
:C09AA05
Ramipril Ramipril, sold under the brand name Altace among others, is an ACE inhibitor type medication used to treat high blood pressure, heart failure, and diabetic kidney disease. It can also be used as a preventative medication in patients over 55 yea ...
:C09AA06
Quinapril Quinapril, sold under the brand name Accupril among others, is a medication used to treat high blood pressure (hypertension), heart failure, and diabetic kidney disease. It is a reasonable initial treatment for high blood pressure. It is taken ...
:C09AA07
Benazepril Benazepril, sold under the brand name Lotensin among others, is a medication used to treat high blood pressure, heart failure, and diabetic kidney disease. It is a reasonable initial treatment for high blood pressure. It is taken by mouth. Vers ...
:C09AA08
Cilazapril Cilazapril is an angiotensin-converting enzyme inhibitor (ACE inhibitor) used for the treatment of hypertension and congestive heart failure. It was patented in 1982 and approved for medical use in 1990. Chemistry Of the eight possible stereo ...
:C09AA09
Fosinopril Fosinopril is an angiotensin converting enzyme (ACE) inhibitor used for the treatment of hypertension and some types of chronic heart failure. Fosinopril is the only phosphonate-containing ACE inhibitor marketed, by Bristol-Myers Squibb under th ...
:C09AA10
Trandolapril Trandolapril is an ACE inhibitor used to treat high blood pressure. It may also be used to treat other conditions. It is similar in structure to another ACE Inhibitor, Ramipril but has a cyclohexane group. It also is a pro-drug and must get metab ...
:C09AA11
Spirapril Spirapril, sold under the brand name Renormax among others, is an ACE inhibitor antihypertensive drug used to treat hypertension. It belongs to dicarboxy group of ACE inhibitors. It was patented in 1980 and approved for medical use in 1995. C ...
:C09AA12 Delapril :C09AA13
Moexipril Moexipril an angiotensin converting enzyme inhibitor (ACE inhibitor) used for the treatment of hypertension and congestive heart failure. Moexipril can be administered alone or with other antihypertensives or diuretics A diuretic () is any sub ...
:C09AA14 Temocapril :C09AA15
Zofenopril Zofenopril ( INN) is a medication that protects the heart and helps reduce high blood pressure. It is an angiotensin-converting enzyme (ACE) inhibitor. In small studies, zofenopril appeared significantly more effective in reducing hypertensio ...
:C09AA16
Imidapril Imidapril (trade name Tanatril) is an ACE inhibitor used as an antihypertensive drug and for the treatment of chronic heart failure. It was patented in 1982 and approved for medical use in 1993. Contraindications Contraindications are hypersen ...


C09B ACE inhibitors, combinations


C09BA ACE inhibitors and diuretics

:C09BA01 Captopril and diuretics :C09BA02 Enalapril and diuretics :C09BA03 Lisinopril and diuretics :C09BA04 Perindopril and diuretics :C09BA05 Ramipril and diuretics :C09BA06 Quinapril and diuretics :C09BA07 Benazepril and diuretics :C09BA08 Cilazapril and diuretics :C09BA09 Fosinopril and diuretics :C09BA12 Delapril and diuretics :C09BA13 Moexipril and diuretics :C09BA15 Zofenopril and diuretics


C09BB ACE inhibitors and calcium channel blockers

:C09BB02 Enalapril and
lercanidipine Lercanidipine (trade name Zanidip, among others) is an antihypertensive (blood pressure lowering) drug. It belongs to the dihydropyridine class of calcium channel blockers, which work by relaxing and opening the blood vessels allowing the blood to ...
:C09BB03 Lisinopril and amlodipine :C09BB04 Perindopril and amlodipine :C09BB05 Ramipril and
felodipine Felodipine is a medication of the calcium channel blocker type which is used to treat high blood pressure. It was patented in 1978 and approved for medical use in 1988. Medical uses Felodipine is used to treat high blood pressure and stable ...
:C09BB06 Enalapril and
nitrendipine Nitrendipine is a dihydropyridine calcium channel blocker. It is used in the treatment of primary (essential) hypertension to decrease blood pressure and can reduce the cardiotoxicity of cocaine. It was patented in 1971 and approved for medi ...
:C09BB07 Ramipril and amlodipine :C09BB10 Trandolapril and verapamil :C09BB12 Delapril and
manidipine Manidipine is a calcium channel blocker (dihydropyridine type) that is used clinically as an antihypertensive Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to pre ...
:C09BB13 Benazepril and amlodipine


C09BX ACE inhibitors, other combinations

:C09BX01 Perindopril, amlodipine and
indapamide Indapamide is a thiazide-like diuretic drug used in the treatment of hypertension, as well as decompensated heart failure. Combination preparations with perindopril (an ACE inhibitor antihypertensive) are available. The thiazide-like diureti ...
:C09BX02 Perindopril and
bisoprolol Bisoprolol, sold under the brand name Zebeta among others, is a beta blocker medication used for heart diseases. This includes tachyarrhythmias, high blood pressure, chest pain from not enough blood flow to the heart, and heart failure. It is t ...
:C09BX03 Ramipril, amlodipine and
hydrochlorothiazide Hydrochlorothiazide is a diuretic medication often used to treat high blood pressure and swelling due to fluid build-up. Other uses include treating diabetes insipidus and renal tubular acidosis and to decrease the risk of kidney stones in th ...
:C09BX04 Perindopril, bisoprolol and amlodipine :C09BX05 Ramipril and bisoprolol :QC09BX90 Benazepril and
pimobendan Pimobendan (INN, or pimobendane; tradenames Vetmedin, Acardi) is a veterinary medication. It is a calcium sensitizer and a selective inhibitor of phosphodiesterase 3 (PDE3) with positive inotropic and vasodilator effects. Pimobendan is used in th ...


C09C

Angiotensin II receptor blocker Angiotensin II receptor blockers (ARBs), formally angiotensin II receptor type 1 (AT1) antagonists, also known as angiotensin receptor blockers, angiotensin II receptor antagonists, or AT1 receptor antagonists, are a group of pharmaceuticals tha ...
s (ARBs), plain


C09CA Angiotensin II receptor blockers (ARBs), plain

:C09CA01
Losartan Losartan, sold under the brand name Cozaar among others, is a medication used to treat high blood pressure (hypertension). It is in the angiotensin receptor blocker (ARB) family of medication, and is considered protective of the kidneys. Besid ...
:C09CA02
Eprosartan Eprosartan is an angiotensin II receptor antagonist used for the treatment of high blood pressure. It is marketed in the United States as ''Teveten'' by Abbvie, the spin-off of the pharmaceutical discovery division of Abbott Laboratories; it is ...
:C09CA03
Valsartan Valsartan, sold under the brand name Diovan among others, is a medication used to treat high blood pressure, heart failure, and diabetic kidney disease. It belongs to a class of medications referred to as angiotensin II receptor blockers (ARB ...
:C09CA04
Irbesartan Irbesartan, sold under the brand name Avapro among others, is a medication used to treat high blood pressure, heart failure, and diabetic kidney disease. It is a reasonable initial treatment for high blood pressure. It is taken by mouth. Versio ...
:C09CA05 Tasosartan :C09CA06
Candesartan Candesartan is an angiotensin receptor blocker used mainly for the treatment of high blood pressure and congestive heart failure. Candesartan has a very low maintenance dose. The metabolism for the drug is unique as it is a cascading prodrug. ...
:C09CA07
Telmisartan Telmisartan, sold under the brand name Micardis among others, is a medication used to treat high blood pressure, heart failure, and diabetic kidney disease. It is a reasonable initial treatment for high blood pressure. It is taken by mouth. V ...
:C09CA08
Olmesartan medoxomil Olmesartan, sold under the trade name Benicar among others, is a medication used to treat high blood pressure, heart failure, and diabetic kidney disease. It is a reasonable initial treatment for high blood pressure. It is taken by mouth. Versi ...
:C09CA09
Azilsartan medoxomil Azilsartan is an angiotensin II receptor antagonist used in the treatment of hypertension, developed by Takeda. It is marketed in tablet form under the brand name Edarbi as the prodrug azilsartan medoxomil. The most common adverse reaction in ...
:C09CA10
Fimasartan Fimasartan is a non-peptide angiotensin II receptor antagonist (ARB) used for the treatment of hypertension and heart failure. Through oral administration, fimasartan blocks angiotensin II receptor type 1 (AT1 receptors), reducing pro-hypertensiv ...


C09D Angiotensin II receptor blockers (ARBs), combinations


C09DA Angiotensin II receptor blockers (ARBs) and diuretics

:C09DA01 Losartan and diuretics :C09DA02 Eprosartan and diuretics :C09DA03 Valsartan and diuretics :C09DA04 Irbesartan and diuretics :C09DA06 Candesartan and diuretics :C09DA07 Telmisartan and diuretics :C09DA08 Olmesartan medoxomil and diuretics :C09DA09 Azilsartan medoxomil and diuretics :C09DA10 Fimasartan and diuretics


C09DB Angiotensin II receptor blockers (ARBs) and calcium channel blockers

:C09DB01 Valsartan and amlodipine :C09DB02 Olmesartan medoxomil and amlodipine :C09DB04 Telmisartan and amlodipine :C09DB05 Irbesartan and amlodipine :C09DB06 Losartan and amlodipine :C09DB07 Candesartan and amlodipine :C09DB08 Valsartan and lercanidipine :C09DB09 Fimasartan and amlodipine


C09DX Angiotensin II receptor blockers (ARBs), other combinations

:C09DX01 Valsartan, amlodipine and hydrochlorothiazide :C09DX02 Valsartan and
aliskiren Aliskiren (brand names Tekturna and Rasilez) is the first in a class of drugs called direct renin inhibitors. It is used for essential (primary) hypertension. While used for high blood pressure, other better studied medications are typically reco ...
:C09DX03 Olmesartan medoxomil, amlodipine and hydrochlorothiazide :C09DX04 Valsartan and sacubitril :C09DX05 Valsartan and nebivolol :C09DX06 Candesartan, amlodipine and hydrochlorothiazide :C09DX07 Irbesartan, amlodipine and hydrochlorothiazide :C09DX08 Telmisartan, amlodipine and hydrochlorothiazide


C09X Other agents acting on the renin–angiotensin system


C09XA Renin-inhibitors

:C09XA01
Remikiren Remikiren is a renin inhibitor under development for the treatment of hypertension (high blood pressure). It was first developed by Hoffmann–La Roche F. Hoffmann-La Roche AG, commonly known as Roche, is a Swiss multinational healthcare ...
:C09XA02
Aliskiren Aliskiren (brand names Tekturna and Rasilez) is the first in a class of drugs called direct renin inhibitors. It is used for essential (primary) hypertension. While used for high blood pressure, other better studied medications are typically reco ...
:C09XA52 Aliskiren and hydrochlorothiazide :C09XA53 Aliskiren and amlodipine :C09XA54 Aliskiren, amlodipine and hydrochlorothiazide


References

{{Agents acting on the renin–angiotensin system C09