Temocapril
Temocapril (also known as ''temocaprilum'' atin brand name Acecol) is an ACE inhibitor. It was not approved for use in the US. It is administered as inactive prodrug A prodrug is a pharmacologically inactive medication or compound that, after intake, is metabolized (i.e., converted within the body) into a pharmacologically active drug. Instead of administering a drug directly, a corresponding prodrug can be ..., then converted to its active metabolite, temocaprilat.Yasunari, K., Maeda, K., Nakamura, M., Watanabe, T., Yoshikawa, J., & Asada, A. (2004). Pharmacological and clinical studies with temocapril, an angiotensin converting enzyme inhibitor that is excreted in the bile. Cardiovascular drug reviews, 22(3), 189–198. https://doi.org/10.1111/j.1527-3466.2004.tb00140.x It was patented in 1984 and approved for medical use in 1994. References ACE inhibitors Acetic acids Enantiopure drugs Ethyl esters Lactams Prodrugs Thiophenes Carboxylate esters Thiaze ...
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