Jessica Polka is a biochemist and the co-founder and the former Executive Director of ASAPbio (Accelerating Science and Publication in biology), a non-profit initiative promoting innovation and transparency via
preprint
In academic publishing, a preprint is a version of a scholarly or scientific paper that precedes formal peer review and publication in a peer-reviewed scholarly or scientific journal. The preprint may be available, often as a non-typeset versi ...
s and
open peer review
Open peer review is the various possible modifications of the traditional scholarly peer review process. The three most common modifications to which the term is applied are:
# Open identities: Authors and reviewers are aware of each other's iden ...
. She currently serves as the Program Director for Open Science at Astera.
Education
Polka received a BS in biology from the
University of North Carolina at Chapel Hill
The University of North Carolina at Chapel Hill (UNC, UNC–Chapel Hill, or simply Carolina) is a public university, public research university in Chapel Hill, North Carolina, United States. Chartered in 1789, the university first began enrolli ...
in 2007. While there, she was a Morehead Scholar. She obtained a Ph.D. in biochemistry from the
University of California, San Francisco
The University of California, San Francisco (UCSF) is a Public university, public Land-grant university, land-grant research university in San Francisco, California, United States. It is part of the University of California system and is dedic ...
under the supervision of Dyche Mullins in 2012.
Career
In 2013 Polka became a research fellow in the department of Systems Biology at
Harvard Medical School
Harvard Medical School (HMS) is the medical school of Harvard University and is located in the Longwood Medical and Academic Area, Longwood Medical Area in Boston, Massachusetts. Founded in 1782, HMS is the third oldest medical school in the Un ...
with
Pamela Silver as advisor.
She was also held a visiting scholar at the
Whitehead Institute in Massachusetts. Polka conducted research in the assembly, function, and applications of protein polymers in
bacteria
Bacteria (; : bacterium) are ubiquitous, mostly free-living organisms often consisting of one Cell (biology), biological cell. They constitute a large domain (biology), domain of Prokaryote, prokaryotic microorganisms. Typically a few micr ...
, such as membrane-breaking protein needles called
R bodies. Polka's work on R bodies was discussed in the American magazine ''
The Atlantic
''The Atlantic'' is an American magazine and multi-platform publisher based in Washington, D.C. It features articles on politics, foreign affairs, business and the economy, culture and the arts, technology, and science.
It was founded in 185 ...
,'' and covered by the
American Chemical Society
The American Chemical Society (ACS) is a scientific society based in the United States that supports scientific inquiry in the field of chemistry. Founded in 1876 at New York University, the ACS currently has more than 155,000 members at all ...
. Polka discovered that
carboxysome, a protein organelle in
cyanobacteria
Cyanobacteria ( ) are a group of autotrophic gram-negative bacteria that can obtain biological energy via oxygenic photosynthesis. The name "cyanobacteria" () refers to their bluish green (cyan) color, which forms the basis of cyanobacteri ...
, grows like a crystal until it is coated by a layer of shell proteins.

Polka was co-chair of the
American Society for Cell Biology's COMPASS (Committee for Postdocs and Students) during 2013 and 2014.
Improving research culture
Polka is on the steering committee for Rescuing Biomedical Research, an initiative to discuss solutions to problems addressed in the April 2014 ''
PNAS
''Proceedings of the National Academy of Sciences of the United States of America'' (often abbreviated ''PNAS'' or ''PNAS USA'') is a peer-reviewed multidisciplinary scientific journal. It is the official journal of the National Academy of S ...
'' article "Rescuing US biomedical research from its systemic flaws".
Polka is recognised as having insight into issues surrounding open peer review, preprint and early career progression, and has been quoted in numerous articles by ''
Nature
Nature is an inherent character or constitution, particularly of the Ecosphere (planetary), ecosphere or the universe as a whole. In this general sense nature refers to the Scientific law, laws, elements and phenomenon, phenomena of the physic ...
'' and ''
Science
Science is a systematic discipline that builds and organises knowledge in the form of testable hypotheses and predictions about the universe. Modern science is typically divided into twoor threemajor branches: the natural sciences, which stu ...
'' on these topics. In 2015, Polka and Viviane Callier wrote an article for the careers column in ''Nature'' where they argue that funding agencies should support more than 16% of postdocs through fellowships. This would allow postdocs to "strike out away from the beaten path
ndwill bring fresh ideas and approaches to the table".
Future of Research
Polka was one of the organisers of the first Future of Research Symposium in Boston in 2014. She was on the executive committee until she became president of the board of directors in 2016. Polka is involved in creating debate amongst early-career scientists about the financial, historical and political influences on academic research. Future of Research was awarded the People of the Year award in 2015 by
Science
Science is a systematic discipline that builds and organises knowledge in the form of testable hypotheses and predictions about the universe. Modern science is typically divided into twoor threemajor branches: the natural sciences, which stu ...
journal for their "efforts to empower early-career and aspiring scientists...".
ASAPbio
Polka was a founder of ASAPbio which began in 2015 after
Ron Vale showed that
University of California, San Francisco
The University of California, San Francisco (UCSF) is a Public university, public Land-grant university, land-grant research university in San Francisco, California, United States. It is part of the University of California system and is dedic ...
students were taking a long time to publish and proposed that
preprint
In academic publishing, a preprint is a version of a scholarly or scientific paper that precedes formal peer review and publication in a peer-reviewed scholarly or scientific journal. The preprint may be available, often as a non-typeset versi ...
ing might mitigate the issue. Vale recruited Polka,
Daniel Colon-Ramos and
Harold Varmus which led to the first ASAPbio meeting in February 2016 attended by scientists, representatives from funding agencies, journals and preprint servers. The meeting Polka led was widely recognized as a turning point in scholarly communication
and a catalyst moment in the so-called "preprint revolution" in biology and science more generally. Polka began working full-time at ASAPbio in 2016 after funding was granted from the
Simons Foundation,
Sloan Foundation,
Arnold Foundation, and
Gordon and Betty Moore Foundation.
In 2016 Polka was described in the journal ''Nature'' as an "agent of change" for explaining how junior researchers can increase the impact of their work. For instance, ASAPbio encourages preprints within biology.
ASAPbio tries to mitigate the effect of lengthy waiting times before publications are reviewed and published, following the example of physics, computer science and maths, fields that have already adopted preprints. She has also taken an interest in strategies for preventing sexual harassment in the scientific community.
In 2017,
PLOScast interviewed Polka about her work which contributes to the changing way that science is published.
Since 2019, ASAPBio has begun to host open databases to collate information about academic publishing practices.
ReimagineReview tracks the different peer review policies and models of academic journals, with a focus on experimental forms of peer review.
The Transpose database extends on this to cover journal policies including on peer review, co-reviewing, preprints, licensing, and versioning.
Awards and honors
*
Beckman Coulter Distinguished Graduate Student Prize (
American Society for Cell Biology) (2013)
*
Jane Coffin Childs Fellowship (2013–2016)
References
External links
*
Rescuing Biomedical Research
ASAPbio
{{DEFAULTSORT:Polka, Jessica
American systems biologists
Harvard Medical School faculty
Living people
American molecular biologists
American women molecular biologists
University of California alumni
Synthetic biologists
Open content activists
University of North Carolina at Chapel Hill alumni
21st-century American chemists
21st-century biochemists
21st-century American women scientists
American women biochemists
Year of birth missing (living people)
American women academics