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Harold Varmus
Harold Eliot Varmus (born December 18, 1939) is an American Nobel Prize-winning scientist. He is currently the Lewis Thomas University Professor of Medicine at Weill Cornell Medicine and a senior associate at the New York Genome Center. He was a co-recipient (along with J. Michael Bishop) of the 1989 Nobel Prize in Physiology or Medicine for discovery of the cellular origin of retroviral oncogenes. He was also the director of the National Institutes of Health from 1993 to 1999 and the 14th Director of the National Cancer Institute from 2010 to 2015, a post to which he was appointed by President Barack Obama. Early life and education Varmus was born on December 18, 1939, to Beatrice, a social service worker, and Frank Varmus, a physician, Jewish parents of Eastern European descent, in Oceanside, New York.''Les Prix Nobel.'' The Nobel Prizes 1989, Editor Tore Frängsmyr, Nobel Foundation, Stockholm, 1990. In 1957, he graduated from Freeport High School in Freeport, New Yor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Cancer Institute
The National Cancer Institute (NCI) coordinates the United States National Cancer Program and is part of the National Institutes of Health (NIH), which is one of eleven agencies that are part of the U.S. Department of Health and Human Services. The NCI conducts and supports research, training, health information dissemination, and other activities related to the causes, prevention, diagnosis, and treatment of cancer; the supportive care of cancer patients and their families; and cancer survivorship. NCI is the oldest and has the largest budget and research program of the 27 institutes and centers of the NIH ($6.9 billion in 2020). It fulfills the majority of its mission via an extramural program that provides grants for cancer research. Additionally, the National Cancer Institute has intramural research programs in Bethesda, Maryland, and at the Frederick National Laboratory for Cancer Research at Fort Detrick in Frederick, Maryland. The NCI receives more than in funding e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harvard University
Harvard University is a Private university, private Ivy League research university in Cambridge, Massachusetts, United States. Founded in 1636 and named for its first benefactor, the History of the Puritans in North America, Puritan clergyman John Harvard (clergyman), John Harvard, it is the oldest institution of higher learning in the United States. Its influence, wealth, and rankings have made it one of the most prestigious universities in the world. Harvard was founded and authorized by the Massachusetts General Court, the governing legislature of Colonial history of the United States, colonial-era Massachusetts Bay Colony. While never formally affiliated with any Religious denomination, denomination, Harvard trained Congregationalism in the United States, Congregational clergy until its curriculum and student body were gradually secularized in the 18th century. By the 19th century, Harvard emerged as the most prominent academic and cultural institution among the Boston B ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
New York Genome Center
The New York Genome Center (NYGC) is an independent 501(c)(3) nonprofit academic research institution in New York, New York. It serves as a multi-institutional collaborative hub focused on the advancement of genomic science and its application to drive novel biomedical discoveries. NYGC's areas of focus include the development of computational and experimental genomic methods and disease-focused research to better understand the genetic basis of cancer, neurodegenerative disease, and neuropsychiatric disease. In 2020, the NYGC also has directed its expertise to COVID-19 genomics research. Purpose and organization The Center leverages strengths in whole genome sequencing, genomic analysis, and development of genomic tools to advance genomic discovery. Its faculty hold joint tenure-track appointments at its member institutions and lead independent research labs at the center. NYGC's scientists bring a multidisciplinary and in-depth approach to the field of genomics, conducting r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nobel Prize
The Nobel Prizes ( ; ; ) are awards administered by the Nobel Foundation and granted in accordance with the principle of "for the greatest benefit to humankind". The prizes were first awarded in 1901, marking the fifth anniversary of Alfred Nobel, Alfred Nobel's death. The original Nobel Prizes covered five fields: Nobel Prize in Physics, physics, Nobel Prize in Chemistry, chemistry, Nobel Prize in Physiology or Medicine, physiology or medicine, Nobel Prize in Literature, literature, and Nobel Peace Prize, peace, specified in Nobel's will. A sixth prize, the Nobel Memorial Prize in Economic Sciences, Prize in Economic Sciences, was established in 1968 by Sveriges Riksbank (Sweden's central bank) in memory of Alfred Nobel. The Nobel Prizes are widely regarded as the most prestigious awards available in their respective fields.Nobel Prize#Shalev69, Shalev, p. 8. Except in extraordinary circumstances, such as war, all six prizes are given annually. Each recipient, known as a laur ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Americans
Americans are the Citizenship of the United States, citizens and United States nationality law, nationals of the United States, United States of America.; ; Law of the United States, U.S. federal law does not equate nationality with Race (human categorization), race or ethnicity but rather with citizenship.* * * * * * * The U.S. has 37 American ancestries, ancestry groups with more than one million individuals. White Americans form the largest race (human classification), racial and ethnic group at 61.6% of the U.S. population, with Non-Hispanic whites, non-Hispanic Whites making up 57.8% of the population. Hispanic and Latino Americans form the second-largest group and are 18.7% of the American population. African Americans, Black Americans constitute the country's third-largest ancestry group and are 12.4% of the total U.S. population. Asian Americans are the country's fourth-largest group, composing 6% of the American population. The country's 3.7 million Native Americans i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vannevar Bush Award
The National Science Board established the Vannevar Bush Award ( ) in 1980 to honor Vannevar Bush's unique contributions to public service. The annual award recognizes an individual who, through public service activities in science and technology, has made an outstanding "contribution toward the welfare of mankind and the Nation." The recipient of the award receives a bronze medal struck in the memory of Dr. Bush. Vannevar Bush (1890–1974) was a prominent scientist, adviser to US presidents, and the force behind the establishment of the National Science Foundation. In 1945, at the request of President Franklin D. Roosevelt, he wrote a famous essay entitled ''Science, the Endless Frontier'' which recommended that a foundation be established by the United States Congress to serve as a focal point for the USA Federal Government's support and encouragement of research and education in science and technology as well as the development of a national science policy. The legislation c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nobel Prize In Physiology Or Medicine
The Nobel Prize in Physiology or Medicine () is awarded yearly by the Nobel Assembly at the Karolinska Institute for outstanding discoveries in physiology or medicine. The Nobel Prize is not a single prize, but five separate prizes that, according to Alfred Nobel's 1895 will, are awarded "to those who, during the preceding year, have conferred the greatest benefit to humankind". Nobel Prizes are awarded in the fields of Physics, Medicine or Physiology, Chemistry, Literature, and Peace. The Nobel Prize is presented annually on the anniversary of Alfred Nobel's death, 10 December. As of 2024, 115 Nobel Prizes in Physiology or Medicine have been awarded to 229 laureates, 216 men and 13 women. The first one was awarded in 1901 to the German physiologist, Emil von Behring, for his work on serum therapy and the development of a vaccine against diphtheria. The first woman to receive the Nobel Prize in Physiology or Medicine, Gerty Cori, received it in 1947 for her role in elucida ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
PLOS
PLOS (for Public Library of Science; PLoS until 2012) is a nonprofit publisher of open-access journals in science, technology, and medicine and other scientific literature, under an open-content license. It was founded in 2000 and launched its first journal, '' PLOS Biology'', in October 2003. As of 2024, PLOS publishes 14 academic journals, including 7 journals indexed within the Science Citation Index Expanded, and consequently 7 journals ranked with an impact factor. PLOS journals are included in the Directory of Open Access Journals (DOAJ). PLOS is also a member of the Open Access Scholarly Publishers Association (OASPA), a participating publisher and supporter of the Initiative for Open Citations, and a member of the Committee on Publication Ethics (COPE). History The Public Library of Science began in 2000 with an online petition initiative by Nobel Prize winner Harold Varmus, formerly director of the National Institutes of Health and at that time director ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oncogene
An oncogene is a gene that has the potential to cause cancer. In tumor cells, these genes are often mutated, or expressed at high levels.Kimball's Biology Pages. "Oncogenes" Free full text Most normal cells undergo a preprogrammed rapid cell death () if critical functions are altered and then malfunction. Activated oncogenes can cause those cells designated for apoptosis to survive and proliferate instead. Most oncogenes began as proto-oncogenes: normal genes involved in cell growth and proliferation or inhibition of apoptosis. If, through mutation, normal genes promoting cellular growth are up-regulated (gain-of-function mutation), they predispose the cel ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Retrovirus
A retrovirus is a type of virus that inserts a DNA copy of its RNA genome into the DNA of a host cell that it invades, thus changing the genome of that cell. After invading a host cell's cytoplasm, the virus uses its own reverse transcriptase enzyme to produce DNA from its RNA genome, the reverse of the usual pattern, thus ''retro'' (backward). The new DNA is then retroviral integration, incorporated into the host cell genome by an integrase enzyme, at which point the retroviral DNA is referred to as a provirus. The host cell then treats the viral DNA as part of its own genome, transcribing and translating the viral genes along with the cell's own genes, producing the proteins required to assemble new copies of the virus. Many retroviruses cause serious diseases in humans, other mammals, and birds. Retroviruses have many subfamilies in three basic groups. * Oncovirus, Oncoretroviruses (cancer-causing retroviruses) include human T-lymphotropic virus (HTLV) causing a type of leuk ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tyler Jacks
Tyler Jacks is a David H. Koch Professor of Biology at the Massachusetts Institute of Technology (MIT), a long-time HHMI investigator, and founding director of the David H. Koch Institute for Integrative Cancer Research, which brings together biologists and engineers to improve detection, diagnosis, and treatment of cancer. Dr. Jacks is a member of the board of directors of Thermo Fisher Scientific and Amgen, two of the major biotechnology corporations in the world. He is the president of Break Through Cancer and a member of the coard of overseers, the larger of two governing boards of Harvard University. Early life Tyler Jacks graduated magna cum laude with highest honors in biology from Harvard University in 1983 and earned a PhD in biochemistry from the University of California, San Francisco, in 1988 under the guidance of Nobel Laureate Harold Varmus. He then went on to do postdoctoral research at MIT in the Whitehead Institute in the lab of Robert Weinberg. Career He was ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kirsten Bibbins-Domingo
Kirsten Bibbins-Domingo is an American epidemiologist and physician. She is the 17th Editor in Chief of the Journal of the American Medical Association (JAMA) and the JAMA Network. She is Professor of Epidemiology and Biostatistics and the Lee Goldman, MD Endowed Professor of Medicine at University of California, San Francisco. She is a general internist and attending physician at San Francisco General Hospital. Bibbins-Domingo is a recognized expert in prevention and health equity and has published more than 200 peer-reviewed original research articles. She is a cardiovascular disease epidemiologist whose work focuses on clinical and public health approaches to prevention, particularly in young adults. She served as the chair, vice-chair, and member of the United States Preventive Services Task Force from 2010 to 2017. At UCSF she served as the inaugural Vice Dean for Population Health and Health Equity in the UCSF School of Medicine, and was the Chair of the UCSF Department ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
