AM-2232 (1-(4-cyanobutyl)-3-(naphthalen-1-oyl)indole) is a drug that acts as a potent but unselective
agonist
An agonist is a chemical that activates a Receptor (biochemistry), receptor to produce a biological response. Receptors are Cell (biology), cellular proteins whose activation causes the cell to modify what it is currently doing. In contrast, an R ...
for the
cannabinoid receptors, with a
''K''i of 0.28 nM at
CB1 and 1.48 nM at
CB2.
In the United States, all CB
1 receptor agonists of the 3-(1-naphthoyl)indole class such as AM-2232 are
Schedule I Controlled Substance
The Controlled Substances Act (CSA) is the statute establishing federal U.S. drug policy under which the manufacture, importation, possession, use, and distribution of certain substances is regulated. It was passed by the 91st United State ...
s.
See also
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AM-694
AM-694 (1-(5-fluoropentyl)-3-(2-iodobenzoyl)indole) is a designer drug that acts as a potent and selective agonist for the cannabinoid receptor CB1. It is used in scientific research for mapping the distribution of CB1 receptors.
Pharmacolog ...
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AM-1235
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AM-2233
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FUBIMINA
FUBIMINA (also known as BIM-2201, BZ-2201 and FTHJ) is a synthetic cannabinoid that is the benzimidazole structural analog, analog of AM-2201 and has been used as an active ingredient in synthetic cannabis products. It was first identified in J ...
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JWH-018
JWH-018 (1-pentyl-3-(1-naphthoyl)indole, NA-PIMO or AM-678) is an analgesic chemical from the naphthoylindole family that acts as a full agonist at both the CB1 and CB2 cannabinoid receptors, with some selectivity for CB2. It produces effe ...
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List of AM cannabinoids
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List of JWH cannabinoids
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O-774
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O-1057
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O-1812
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THJ-2201
THJ-2201 is an indazole-based synthetic cannabinoid that presumably acts as a potent agonist of the CB1 receptor, CB1 receptor and has been sold online as a designer drug.
It is a structural analog of AM-2201 in which the central indole ring h ...
References
Naphthoylindoles
Nitriles
AM cannabinoids
Designer drugs
{{cannabinoid-stub