Various fringe theories have arisen to speculate about purported alternative origins for the
human immunodeficiency virus
The human immunodeficiency viruses (HIV) are two species of ''Lentivirus'' (a subgroup of retrovirus) that infect humans. Over time, they cause AIDS, acquired immunodeficiency syndrome (AIDS), a condition in which progressive failure of th ...
(HIV) and the
acquired immunodeficiency syndrome
The human immunodeficiency virus (HIV) is a retrovirus that attacks the immune system. Without treatment, it can lead to a spectrum of conditions including acquired immunodeficiency syndrome (AIDS). It is a preventable disease. It can ...
(AIDS), with claims ranging from it being due to accidental exposure to supposedly purposeful acts. Several inquiries and investigations have been carried out as a result, and each of these theories has consequently been determined to be based on unfounded and/or false information. HIV has been shown to have evolved from or be closely related to the
simian immunodeficiency virus
Simian immunodeficiency virus (SIV) is a species of retrovirus that cause persistent infections in at least 45 species of non-human primates. Based on analysis of strains found in four species of monkeys from Bioko Island, which was isolated fr ...
(SIV) in West Central Africa sometime in the early 20th century. HIV was discovered in the 1980s by the French scientist
Luc Montagnier
Luc Montagnier ( , ; 18 August 1932 – 8 February 2022) was a French virologist and joint recipient, with and , of the 2008 Nobel Prize in Physiology or Medicine for his discovery of the human immunodeficiency virus ( HIV). He worked as a rese ...
. Before the 1980s, HIV was an unknown deadly disease.
Discredited theories
Duesenberg hypothesis
The
Duesberg hypothesis
The Duesberg hypothesis is the claim that AIDS is not caused by HIV, but instead that AIDS is caused by noninfectious factors such as recreational and pharmaceutical drug use and that HIV is merely a harmless passenger virus. The hypothesis was p ...
was developed by American biologist
Peter Duesberg
Peter Heinz Hermann Duesberg (born December 2, 1936) is a German-American molecular biologist and a professor of molecular and cell biology at the University of California, Berkeley. He is known for his early research into the genetic aspects o ...
who argued AIDS was caused by noninfectious factors, such as recreational and pharmaceutical drug use, and that HIV is merely a harmless passenger virus. This hypothesis is widely regarded as lacking supporting evidence, overlooking contrary evidence, and being conclusively refuted.
Smallpox vaccination theory
In 1987 there was some consideration given to the possibility that the "AIDS epidemic may have been triggered by the mass vaccination campaign which eradicated
smallpox
Smallpox was an infectious disease caused by Variola virus (often called Smallpox virus), which belongs to the genus '' Orthopoxvirus''. The last naturally occurring case was diagnosed in October 1977, and the World Health Organization (W ...
". An article in ''
The Times
''The Times'' is a British Newspaper#Daily, daily Newspaper#National, national newspaper based in London. It began in 1785 under the title ''The Daily Universal Register'', adopting its modern name on 1 January 1788. ''The Times'' and its si ...
'' suggested this, attributing to an unnamed "adviser to WHO" the quote "I believe the smallpox vaccine theory is the explanation to the explosion of AIDS". It is now thought that the
smallpox vaccine
The smallpox vaccine is used to prevent smallpox infection caused by the variola virus. It is the first vaccine to have been developed against a contagious disease. In 1796, British physician Edward Jenner demonstrated that an infection with th ...
causes serious complications for people who already have impaired immune systems, and the ''Times'' article described the case of a military recruit with "dormant HIV" who died within months of receiving it. But no citation was provided regarding people who did not previously have HIV. Currently several professional publications describe HIV as a
contraindication
In medicine, a contraindication is a condition (a situation or factor) that serves as a reason not to take a certain medical treatment due to the harm that it would cause the patient. Contraindication is the opposite of indication, which is a rea ...
for the smallpox vaccine—both for an infected person and their sexual partners and household members. Some conspiracy theorists propose an expanded hypothesis in which the smallpox vaccine was deliberately contaminated with HIV.
In contrast, a research article was published in 2010 suggesting that it might have been the actual eradication of smallpox and the subsequent "ending" of the mass vaccination campaign that contributed to the sudden emergence of HIV. The theory was the possibility that immunization against smallpox "might play a role in providing an individual with some degree of protection to subsequent HIV infection and/or disease progression." Regardless of the effects of the smallpox vaccine itself, its use in practice in Africa is one of the categories of un-sterile
injections that may have contributed to the spread and mutation of the immunodeficiency viruses.
Hepatitis B vaccine (HBV) theory
The dermatologist Alan Cantwell, in self-published books entitled ''AIDS and the Doctors of Death: An Inquiry into the Origin of the AIDS Epidemic'' (1988) and ''Queer Blood: The Secret AIDS Genocide Plot'' (1993), said that HIV is a
genetically modified organism
A genetically modified organism (GMO) is any organism whose genetic material has been altered using genetic engineering techniques. The exact definition of a genetically modified organism and what constitutes genetic engineering varies, with ...
developed by U.S. Government scientists. The virus was then introduced into the population through
hepatitis B
Hepatitis B is an infectious disease caused by the '' hepatitis B virus'' (HBV) that affects the liver; it is a type of viral hepatitis. It can cause both acute and chronic infection.
Many people have no symptoms during an initial infection. ...
(via the
hepatitis B vaccine
Hepatitis B vaccine is a vaccine that prevents hepatitis B. The first dose is recommended within 24 hours of birth with either two or three more doses given after that. This includes those with poor immune function such as from HIV/AIDS and ...
) experiments performed on gay and bisexual men between 1978 and 1981 in major U.S. cities. Cantwell claims that these experiments were directed by
Wolf Szmuness
Wolf Szmuness (March 12, 1919 – June 6, 1982) was a Polish-born epidemiology, epidemiologist who immigrated to and worked in the United States. He conducted research at the New York Blood Center and, from 1973, he was director of the Center's epi ...
, and that there was an ongoing government cover-up of the origins of the AIDS epidemic. Similar theories have been advanced by Robert B. Strecker, Matilde Krim, and
Milton William Cooper
Milton William "Bill" Cooper (May 6, 1943 – November 5, 2001) was an American conspiracy theorist, radio broadcaster, and author known for his 1991 book ''Behold a Pale Horse'', in which he warned of multiple global conspiracies, some i ...
.
Oral polio vaccine (OPV) theory
In the 1999 version of his
OPV AIDS hypothesis
The Oral polio vaccine AIDS hypothesis (OPV AIDS) is a largely discredited hypothesis which argued the AIDS pandemic originated from live polio vaccines prepared in chimpanzee tissue cultures, accidentally contaminated with simian immunodeficienc ...
, journalist
Edward Hooper proposed that early batches of the
oral polio vaccine
Polio vaccines are vaccines used to prevent poliomyelitis (polio). Two types are used: an inactivated poliovirus given by injection (IPV) and a weakened poliovirus given by mouth (OPV). The World Health Organization (WHO) recommends all chi ...
(OPV) grown in cultures of chimpanzee kidney cells, infected with a chimpanzee virus, were the original source of HIV-1 in Central Africa. A small number of scientists thought this a plausible hypothesis, but later studies found no corroboration.
[Sarah Ramsay 28 April 200]
"Cold water downstream from The River"
''The Lancet'' 357 (9265) p.1343 Other
molecular biology
Molecular biology is a branch of biology that seeks to understand the molecule, molecular basis of biological activity in and between Cell (biology), cells, including biomolecule, biomolecular synthesis, modification, mechanisms, and interactio ...
and
phylogenetic
In biology, phylogenetics () is the study of the evolutionary history of life using observable characteristics of organisms (or genes), which is known as phylogenetic inference. It infers the relationship among organisms based on empirical dat ...
studies also contradict the hypothesis, and
scientific consensus
Scientific consensus is the generally held judgment, position, and opinion of the majority or the supermajority of scientists in a particular field of study at any particular time.
Consensus is achieved through scholarly communication at confer ...
regards it as disproven.
A 2004 article in the journal ''
Nature
Nature is an inherent character or constitution, particularly of the Ecosphere (planetary), ecosphere or the universe as a whole. In this general sense nature refers to the Scientific law, laws, elements and phenomenon, phenomena of the physic ...
'' described the hypothesis as "refuted".
Additional theories
These theories generally attribute HIV's origin to the
US government
The Federal Government of the United States of America (U.S. federal government or U.S. government) is the national government of the United States.
The U.S. federal government is composed of three distinct branches: legislative, execut ...
or its contractors:
Created at Fort Detrick
Jakob Segal
Jakob Segal (17 April 1911 – 30 September 1995) was a Russian-born German biology professor at Humboldt University of Berlin in the former East Germany. He was one of the advocates of the conspiracy theory that HIV was created by the United Sta ...
(1911–1995), a professor at
Humboldt University
The Humboldt University of Berlin (, abbreviated HU Berlin) is a public university, public research university in the central borough of Mitte in Berlin, Germany.
The university was established by Frederick William III of Prussia, Frederick W ...
in then-
East Germany
East Germany, officially known as the German Democratic Republic (GDR), was a country in Central Europe from Foundation of East Germany, its formation on 7 October 1949 until German reunification, its reunification with West Germany (FRG) on ...
, proposed that HIV was engineered at a U.S. military laboratory at
Fort Detrick
Fort Detrick () is a United States Army Futures Command installation located in Frederick, Maryland. Fort Detrick was the center of the U.S. biological weapons program from 1943 to 1969. Since the discontinuation of that program, it has hosted m ...
, by splicing together two other viruses,
Visna and
HTLV-1. According to his theory, the new virus, created between 1977 and 1978, was tested on prison inmates who had volunteered for the experiment in exchange for early release. He further suggested that it was through these prisoners that the virus was spread to the population at large.
At the end of the
Cold War
The Cold War was a period of global Geopolitics, geopolitical rivalry between the United States (US) and the Soviet Union (USSR) and their respective allies, the capitalist Western Bloc and communist Eastern Bloc, which lasted from 1947 unt ...
, former
KGB
The Committee for State Security (, ), abbreviated as KGB (, ; ) was the main security agency of the Soviet Union from 1954 to 1991. It was the direct successor of preceding Soviet secret police agencies including the Cheka, Joint State Polit ...
agents
Vasili Mitrokhin
Vasili Nikitich Mitrokhin (; March 3, 1922 – January 23, 2004) was an archivist for the Soviet Union's foreign intelligence service, the First Chief Directorate of the KGB, who defected to the United Kingdom in 1992. Mitrokhin first offer ...
and
Oleg Gordievsky
Oleg Antonovich Gordievsky (; 10 October 1938 – 4 March 2025) was a colonel of the KGB who became KGB resident-designate (''rezident'') and bureau chief in London.
Gordievsky was a double agent, providing information to the British Secret ...
independently revealed that the Fort Detrick hypothesis was a propaganda operation devised by the KGB's
First Chief Directorate
The First Main Directorate () of the Committee for State Security under the USSR council of ministers (PGU KGB) was the organization responsible for foreign operations and intelligence agency, intelligence activities by providing for the training a ...
codenamed "
Operation Denver". This revelation was later supported by officer Günther Bohnensack of section X of East Germany's
Main Directorate for Reconnaissance
The Main Directorate for Reconnaissance (; , ) was the foreign intelligence service of the Ministry of State Security (''Stasi''), the main security agency of the German Democratic Republic (East Germany), from 1955 to 1990.
The HVA was an in ...
.
It is known that Segal was in close contact with Russian KGB officers and Mitrokhin mentioned him as a central asset of the operation.
[Johanna Lutterroth]
''Aids-Verschwörung. Das Propaganda-Virus des KGB''
Spiegel Geschichte, 2012-06-26 (German) It is not entirely clear whether Segal pursued the hypothesis independently on his own accord or whether he was simply following orders. Segal himself always denied the latter and kept pursuing the hypothesis even after the operation had been canceled and the Cold War had ended.
Conspiracy to decrease the population
In ''Behold a Pale Horse'' (1991), radio broadcaster and author
Milton William Cooper
Milton William "Bill" Cooper (May 6, 1943 – November 5, 2001) was an American conspiracy theorist, radio broadcaster, and author known for his 1991 book ''Behold a Pale Horse'', in which he warned of multiple global conspiracies, some i ...
(1943–2001) proposed that
AIDS
The HIV, human immunodeficiency virus (HIV) is a retrovirus that attacks the immune system. Without treatment, it can lead to a spectrum of conditions including acquired immunodeficiency syndrome (AIDS). It is a Preventive healthcare, pr ...
was the result of a conspiracy to decrease the populations of
blacks
Black is a racial classification of people, usually a political and skin color-based category for specific populations with a mid- to dark brown complexion. Not all people considered "black" have dark skin and often additional phenotypical ch ...
,
Hispanics
The term Hispanic () are people, cultures, or countries related to Spain, the Spanish language, or broadly. In some contexts, especially within the United States, "Hispanic" is used as an ethnic or meta-ethnic term.
The term commonly appli ...
, and
homosexuals
Homosexuality is romantic attraction, sexual attraction, or sexual behavior between people of the same sex or gender. As a sexual orientation, homosexuality is "an enduring pattern of emotional, romantic, and/or sexual attractions" exc ...
.
Prevalence of conspiracy beliefs
According to Phil Wilson, executive director of the Black AIDS Institute in Los Angeles, conspiracy theories are becoming a barrier to the prevention of AIDS since people start to believe that no matter what measures they take, they can still be prone to contracting this disease. A 2005 study suggests this makes them less careful when engaging in practices that put them at risk because they believe there is no point.
"Nearly half of the 500 African Americans surveyed said that HIV is man-made. More than one-quarter said they believed that AIDS was produced in a government laboratory, and 12 percent believed it was created and spread by the CIA ... At the same time, 75 percent said they believed medical and public health agencies are working to stop the spread of AIDS in black communities."
Prominent endorsers of discredited theories
Nation of Islam
The
Nation of Islam
The Nation of Islam (NOI) is a religious organization founded in the United States by Wallace Fard Muhammad in 1930. A centralized and hierarchical organization, the NOI is committed to black nationalism and focuses its attention on the Afr ...
endorses the view that governments and pharmaceutical companies have pursued genocidal racist policies including the creation and spread of HIV. Consequently, the group called for a boycott of U.S.-sponsored vaccination programs for children. Leonard Horowitz has been cited as influential in the boycott decision.
Wangari Maathai
The 2004
Nobel Peace Prize
The Nobel Peace Prize (Swedish language, Swedish and ) is one of the five Nobel Prizes established by the Will and testament, will of Sweden, Swedish industrialist, inventor, and armaments manufacturer Alfred Nobel, along with the prizes in Nobe ...
laureate and environmental activist
Wangari Maathai Wangari is a name of Kikuyu origin that may refer to:
* Wangari Maathai (1940–2011), Kenyan environmental and political activist
* Catherine Wangari Wainaina (born 1985), Kenyan beauty pageant contestant
* Margaret Wangari Muriuki (born 1986), K ...
was asked by a
''Time'' magazine interviewer if she stood by a previous alleged claim that "AIDS is a biological weapon manufactured by the developed world to wipe out the black race". Maathai responded, "I have no idea who created AIDS and whether it is a biological agent or not. But I do know things like that don't come from the moon. ... I guess there is some truth that must not be too exposed." Maathai subsequently issued a written statement in December 2004: "I neither say nor believe that the virus was developed by white people or white powers in order to destroy the African people. Such views are wicked and destructive."
from the Green Belt Movement website- Wangari Maathai's "The Challenge of AIDS in Africa"
.
Manto Tshabalala-Msimang
In 2000 South Africa's Minister of Health Manto Tshabalala-Msimang
Mantombazana "Manto" Edmie Tshabalala-Msimang Order for Meritorious Service, OMSS (née Mali; 9 October 1940 – 16 December 2009) was a South African politician. She was Deputy Minister of Justice from 1996 to 1999 and served as Minister of He ...
received criticism for distributing the chapter from Cooper's book discussing this theory to senior South African government officials. Nicoli Nattrass, a longtime critic of AIDS denialists, criticized Tshabalala-Msimang for lending legitimacy to Cooper's theories and disseminating them in Africa.
See also
* History of HIV/AIDS
AIDS is caused by a human immunodeficiency virus (HIV), which originated in non-human primates
in Central and West Africa. While various sub-groups of the virus acquired human infectivity at different times, the present pandemic had its origins ...
** Timeline of HIV/AIDS
* HIV/AIDS denialism
HIV/AIDS denialism is the belief, despite conclusive evidence to the contrary, that the human immunodeficiency virus (HIV) does not cause acquired immune deficiency syndrome (AIDS). Some of its proponents reject the existence of HIV, while other ...
* HIV/AIDS denialism in South Africa
In South Africa, HIV/AIDS denialism had a significant impact on public health policy from 1999 to 2008, during the presidency of Thabo Mbeki. Mbeki criticized the scientific consensus that HIV is the cause of AIDS beginning shortly after his electi ...
* Operation INFEKTION
Operation Denver (sometimes referred to as "Operation INFEKTION") was an active measure disinformation campaign run by the KGB in the 1980s to plant the idea that the United States had invented HIV/AIDS as part of a biological weapons research ...
* Oral polio vaccine AIDS hypothesis
* SV40
SV40 is an abbreviation for simian vacuolating virus 40 or simian virus 40, a polyomavirus that is found in both monkeys and humans. Like other polyomaviruses, SV40 is a DNA virus that is found to cause tumors in humans and animals, but most ofte ...
* Zoonosis
A zoonosis (; plural zoonoses) or zoonotic disease is an infectious disease of humans caused by a pathogen (an infectious agent, such as a virus, bacterium, parasite, fungi, or prion) that can jump from a non-human vertebrate to a human. When ...
References
External links
*
{{HIV and AIDS
AIDS origin hypotheses
Biological warfare
Health-related conspiracy theories
HIV/AIDS denialism