5-Fluoro-DET (5F-DET, 5-fluoro-''N,N''-diethyltryptamine) is a
tryptamine
Tryptamine is an indolamine metabolite of the essential amino acid tryptophan. The chemical structure is defined by an indole—a fused benzene and pyrrole ring, and a 2-aminoethyl group at the second carbon (third aromatic atom, with the firs ...
derivative related to drugs such as
DET and
5-MeO-DET
5-MeO-DET, also known as 5-methoxy-''N'',''N''-diethyltryptamine is a psychedelic drug of the substituted tryptamine, tryptamine family related to 5-MeO-DMT.
Use and effects
Low dosages (0.5–1 mg) are reported to produce a relaxing body h ...
.
It acts as an inhibitor of the enzyme
myeloperoxidase
Myeloperoxidase (MPO) is a peroxidase enzyme that in humans is encoded by the ''MPO'' gene on chromosome 17. MPO is most abundantly expressed in neutrophils (a subtype of white blood cells), and produces hypohalous acids to carry out their anti ...
,
and is also thought to be an
agonist
An agonist is a chemical that activates a Receptor (biochemistry), receptor to produce a biological response. Receptors are Cell (biology), cellular proteins whose activation causes the cell to modify what it is currently doing. In contrast, an R ...
at the
5-HT2A receptor.
See also
*
5F-DMT
*
5F-MET
*
5F-EPT
*
5F-T
*
6F-DET
References
N,N-Dialkyltryptamines
Diethylamino compounds
Fluoroarenes
5-Halotryptamines
Psychedelic tryptamines
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