2-Fluoromethamphetamine (2-FMA) is a

stimulant Stimulants (also known as central nervous system stimulants, or psychostimulants, or colloquially as uppers) are a class of drugs that increase alertness. They are used for various purposes, such as enhancing attention, motivation, cognition, ...

drug of the

amphetamine Amphetamine (contracted from Alpha and beta carbon, alpha-methylphenethylamine, methylphenethylamine) is a central nervous system (CNS) stimulant that is used in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, an ...

family which has been used as a

designer drug A designer drug is a structural or functional analog of a controlled substance that has been designed to mimic the pharmacological effects of the original drug, while avoiding classification as illegal and/or detection in standard drug tests. ...

. 2-FMA is commonly compared to

lisdexamfetamine Lisdexamfetamine, sold under the brand names Vyvanse and Elvanse among others, is a stimulant medication that is used as a treatment for attention deficit hyperactivity disorder (ADHD) in children and adults and for moderate-to-severe binge ...

(Vyvanse), and

dextroamphetamine Dextroamphetamine (international nonproprietary name, INN: dexamfetamine) is a potent central nervous system (CNS) stimulant and enantiomer of amphetamine that is used in the treatment of attention deficit hyperactivity disorder (ADHD) and narc ...

due to its efficacy as a study or productivity aid. 2-FMA is purported to produce somewhat less euphoria than comparable amphetamines, likely due to its main mechanism of action consisting of norepinephrine reuptake inhibition.

Chemistry

2-Fluoromethamphetamine is fluorinated analogue of

methamphetamine Methamphetamine (contracted from ) is a potent central nervous system (CNS) stimulant that is mainly used as a recreational drug use, recreational or Performance-enhancing substance, performance-enhancing drug and less commonly as a secon ...

, and is a regioisomer of 3-FMA and 4-FMA. It does not activate the serotonin receptors, including 5-HT_2A, unlike most stimulant drugs of the amphetamine family.

Legal status

Canada

As of 1996, 2-FMA is a controlled substance in Canada, due to being an analog of

China

As of October 2015, 2-FMA is a controlled substance in China.

Germany

As of 13 December 2014, 2-FMA is a controlled substance in Germany. It is controlled under Anlage I BtMG (Narcotics Act, Schedule I). Substances controlled under Anlage I BtMG are illegal to manufacture, possess, import, export, buy, sell, procure or dispense it without a license. Violations of the law are punishable by a fine or imprisonment for up to five years.

Ukraine

As of July 2019, 2-FMA is a controlled substance in Ukraine (considered a narcotic).

United States

As a close analog of scheduled

controlled substance A controlled substance is generally a drug or chemical whose manufacture, possession and use is regulated by a government, such as illicitly used drugs or prescription medications that are designated by law. Some treaties, notably the Sing ...

, sale or possession of 2-FMA could be potentially be prosecuted under the

Federal Analogue Act The Federal Analogue Act, , is a section of the United States Controlled Substances Act passed in 1986 which allows any chemical "substantially similar" to a controlled substance listed in Schedule I or II to be treated as if it were listed ...

References

{{DEFAULTSORT:Fluoromethamphetamine, 2- Designer drugs Methamphetamines 2-Fluorophenyl compounds Norepinephrine-dopamine releasing agents Organofluorides