γ-Fagarine (''gamma''-Fagarine) is a

furoquinoline alkaloid Furoquinoline alkaloids are a group of alkaloids with simple structure. Distribution of this group of alkaloids is essentially limited to plant family Rutaceae. The simplest member of this group is dictamnine and most widespread member is skimmi ...

found in numerous plant species, including some used in herbal medicine such as Huáng bǎi (黃栢), one of the fifty fundamental herbs of

traditional Chinese medicine Traditional Chinese medicine (TCM) is an alternative medicine, alternative medical practice drawn from traditional medicine in China. A large share of its claims are pseudoscientific, with the majority of treatments having no robust evidence ...

. Studies ''in vitro'' have shown it to exhibit

mutagen In genetics, a mutagen is a physical or chemical agent that permanently changes genetic material, usually DNA, in an organism and thus increases the frequency of mutations above the natural background level. As many mutations can cause cancer in ...

ic, anti-

malaria Malaria is a Mosquito-borne disease, mosquito-borne infectious disease that affects vertebrates and ''Anopheles'' mosquitoes. Human malaria causes Signs and symptoms, symptoms that typically include fever, Fatigue (medical), fatigue, vomitin ...

, anti-cancer and

antiviral Antiviral drugs are a class of medication used for treating viral infections. Most antivirals target specific viruses, while a broad-spectrum antiviral is effective against a wide range of viruses. Antiviral drugs are a class of antimicrobials ...

properties, but it is unclear what role it plays in the medicinal uses of these plants due to the complex mixture of phytochemicals found alongside it.Li J, Zhao Y, Dai Y, Zhao J. Identification of γ-Fagarine as a novel antiviral agent against respiratory virus (hMPV) infection. ''Virus Res''. 2023 Oct 15;336:199223.

References

{{DEFAULTSORT:Fagarine, γ- Quinoline alkaloids Furoquinolines Methoxy compounds

See also

References