Etienne de Harven (1928-2019) was a Belgian-born

pathologist Pathology is the study of disease. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in the context of modern medical treatme ...

and electron microscopist. Born in

Brussels Brussels, officially the Brussels-Capital Region, (All text and all but one graphic show the English name as Brussels-Capital Region.) is a Communities, regions and language areas of Belgium#Regions, region of Belgium comprising #Municipalit ...

, he did most of his work in

New York City New York, often called New York City (NYC), is the most populous city in the United States, located at the southern tip of New York State on one of the world's largest natural harbors. The city comprises five boroughs, each coextensive w ...

Paris Paris () is the Capital city, capital and List of communes in France with over 20,000 inhabitants, largest city of France. With an estimated population of 2,048,472 residents in January 2025 in an area of more than , Paris is the List of ci ...

and

Toronto Toronto ( , locally pronounced or ) is the List of the largest municipalities in Canada by population, most populous city in Canada. It is the capital city of the Provinces and territories of Canada, Canadian province of Ontario. With a p ...

. He did pioneering research on viruses, mostly related to

murine The Old World rats and mice, part of the subfamily Murinae in the family Muridae, comprise at least 519 species. Members of this subfamily are called murines. In terms of species richness, this subfamily is larger than all mammal families excep ...

leukemia Leukemia ( also spelled leukaemia; pronounced ) is a group of blood cancers that usually begin in the bone marrow and produce high numbers of abnormal blood cells. These blood cells are not fully developed and are called ''blasts'' or '' ...

. He is the former President of the Electron Microscopy Society of America (now

Microscopy Society of America The Microscopy Society of America (MSA), founded in 1942 as The Electron Microscope Society of America, is a non-profit organization that provides microanalytical facilities for studies within the sciences. Currently, there are approximately 3000 me ...

Biography and Work

De Harven obtained his medical degree from the University of Brussels. He later worked at the Institute of Cancer of Villejuif under Charles Oberling and Wilhelm Bernhard, where he made pioneering observations of the structure of

centriole In cell biology a centriole is a cylindrical organelle composed mainly of a protein called tubulin. Centrioles are found in most eukaryotic cells, but are not present in conifers ( Pinophyta), flowering plants ( angiosperms) and most fungi, an ...

s. He was subsequently hired by

Memorial Sloan-Kettering Cancer Center Memorial Sloan Kettering Cancer Center (MSK or MSKCC) is a oncology, cancer treatment and research institution in Manhattan in New York City. MSKCC is one of 72 National Cancer Institute–NCI-designated Cancer Center, designated Comprehen ...

, where he worked alongside Charlotte Friend and studied viruses, mostly in

mice A mouse (: mice) is a small rodent. Characteristically, mice are known to have a pointed snout, small rounded ears, a body-length scaly tail, and a high breeding rate. The best known mouse species is the common house mouse (''Mus musculus' ...

systems and the causation and incidence of leukemia and other malignant

diseases A disease is a particular abnormal condition that adversely affects the structure or function of all or part of an organism and is not immediately due to any external injury. Diseases are often known to be medical conditions that are asso ...

related to those viruses. Later, he provided the first description of viral

budding Budding or blastogenesis is a type of asexual reproduction in which a new organism develops from an outgrowth or bud due to cell division at one particular site. For example, the small bulb-like projection coming out from the yeast cell is kno ...

. While at Sloan-Kettering, de Harven was part of a team which discovered "virus-like particles" in cells taken from patients with

Hodgkin's disease Hodgkin lymphoma (HL) is a type of lymphoma in which cancer originates from a specific type of white blood cell called lymphocytes, where multinucleated Reed–Sternberg cells (RS cells) are present in the lymph nodes. The condition was named a ...

. He became professor of

cell biology Cell biology (also cellular biology or cytology) is a branch of biology that studies the structure, function, and behavior of cells. All living organisms are made of cells. A cell is the basic unit of life that is responsible for the living an ...

at the University of Cornell and later of

pathology Pathology is the study of disease. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in the context of modern medical treatme ...

at the

University of Toronto The University of Toronto (UToronto or U of T) is a public university, public research university whose main campus is located on the grounds that surround Queen's Park (Toronto), Queen's Park in Toronto, Ontario, Canada. It was founded by ...

, where he researched the marking of antigens on the surface of lymphocytes. As former President of the Microscopy Society of America, he published several papers, mostly related to Cancer Pathologies and

electron microscopy An electron microscope is a microscope that uses a beam of electrons as a source of illumination. It uses electron optics that are analogous to the glass lenses of an optical light microscope to control the electron beam, for instance focusing i ...

procedures for viral explorations. De Harven was a prominent skeptic of the scientific validity of the link between HIV and AIDS, one of a group invited in 2000 to

South Africa South Africa, officially the Republic of South Africa (RSA), is the Southern Africa, southernmost country in Africa. Its Provinces of South Africa, nine provinces are bounded to the south by of coastline that stretches along the Atlantic O ...

by president

Thabo Mbeki Thabo Mvuyelwa Mbeki (; born 18 June 1942) is a South African politician who served as the 2nd democratic president of South Africa from 14 June 1999 to 24 September 2008, when he resigned at the request of his party, the African National Cong ...

to serve on a presidential panel on AIDS. He published a book in 2005 entitled ''Les Dix Plus Gros Mensonges sur le SIDA'' (''Ten Lies About AIDS''), in which he denies a connection between the

HIV virus The human immunodeficiency viruses (HIV) are two species of ''Lentivirus'' (a subgroup of retrovirus) that infect humans. Over time, they cause acquired immunodeficiency syndrome (AIDS), a condition in which progressive failure of the imm ...

and

AIDS The HIV, human immunodeficiency virus (HIV) is a retrovirus that attacks the immune system. Without treatment, it can lead to a spectrum of conditions including acquired immunodeficiency syndrome (AIDS). It is a Preventive healthcare, pr ...

, instead attributing the disease to lifestyle and environmental factors. De Harven died in 2019.Rethinking AIDS, the most important HIV/AIDS denialist group, announces Professor De Harven's passing away: http://rethinkingaids.com/index.php/etienne-de-harven-1928-2019

References

{{DEFAULTSORT:Harven, Etienne De Belgian virologists Belgian pathologists 1928 births 2019 deaths Scientists from Brussels Free University of Brussels (1834–1969) alumni Cornell University faculty Academic staff of the University of Toronto HIV/AIDS denialists