''-ine'' is a
suffix
In linguistics, a suffix is an affix which is placed after the stem of a word. Common examples are case endings, which indicate the grammatical case of nouns and adjectives, and verb endings, which form the conjugation of verbs. Suffixes can ca ...
used in
chemistry
Chemistry is the scientific study of the properties and behavior of matter. It is a physical science within the natural sciences that studies the chemical elements that make up matter and chemical compound, compounds made of atoms, molecules a ...
to denote two kinds of
substance. The first is a
chemically basic and
alkaloid
Alkaloids are a broad class of natural product, naturally occurring organic compounds that contain at least one nitrogen atom. Some synthetic compounds of similar structure may also be termed alkaloids.
Alkaloids are produced by a large varie ...
al substance. It was proposed by
Joseph Louis Gay-Lussac in an editorial accompanying a paper by
Friedrich Sertürner describing the isolation of the alkaloid "morphium", which was subsequently renamed to "morphine".
[Sneader W. (2005). ''Drug Discovery: A History'', pp. 90-91. Wiley.] Examples include
quinine
Quinine is a medication used to treat malaria and babesiosis. This includes the treatment of malaria due to ''Plasmodium falciparum'' that is resistant to chloroquine when artesunate is not available. While sometimes used for nocturnal leg ...
,
morphine
Morphine, formerly also called morphia, is an opiate that is found naturally in opium, a dark brown resin produced by drying the latex of opium poppies (''Papaver somniferum''). It is mainly used as an analgesic (pain medication). There are ...
and
guanidine.
The second usage is to denote a
hydrocarbon
In organic chemistry, a hydrocarbon is an organic compound consisting entirely of hydrogen and carbon. Hydrocarbons are examples of group 14 hydrides. Hydrocarbons are generally colourless and Hydrophobe, hydrophobic; their odor is usually fain ...
of the
second degree of unsaturation. Examples include
hexine and
heptine.
With simple hydrocarbons, this usage is identical to the
IUPAC
The International Union of Pure and Applied Chemistry (IUPAC ) is an international federation of National Adhering Organizations working for the advancement of the chemical sciences, especially by developing nomenclature and terminology. It is ...
suffix
-yne.
In common and literary adjectives (e.g. ''asinine, canine, feline, ursine''), the suffix is usually pronounced or in some words alternatively . For demonyms (e.g. ''Levantine, Byzantine, Argentine'') it is usually or . But in chemistry, it is usually pronounced or depending on the word it appears in and the
accent of the speaker. In a few words (for example, ''
quinine
Quinine is a medication used to treat malaria and babesiosis. This includes the treatment of malaria due to ''Plasmodium falciparum'' that is resistant to chloroquine when artesunate is not available. While sometimes used for nocturnal leg ...
'', ''
iodine'' and ''
strychnine''), the sound is normal in some accents. ''
Gasoline
Gasoline ( North American English) or petrol ( Commonwealth English) is a petrochemical product characterized as a transparent, yellowish, and flammable liquid normally used as a fuel for spark-ignited internal combustion engines. When for ...
'' ends with ; ''
glycerine'' more often with than with . In ''
caffeine
Caffeine is a central nervous system (CNS) stimulant of the methylxanthine chemical classification, class and is the most commonly consumed Psychoactive drug, psychoactive substance globally. It is mainly used for its eugeroic (wakefulness pr ...
'', the suffix has merged with the ''e'' in the root, for stressed ; in ''gasoline'' and ''margarine'' as well the suffix is stressed by some people.
Some
elements of the
periodic table
The periodic table, also known as the periodic table of the elements, is an ordered arrangement of the chemical elements into rows (" periods") and columns (" groups"). It is an icon of chemistry and is widely used in physics and other s ...
(namely the
halogens, in the Group 17) have this suffix:
fluorine
Fluorine is a chemical element; it has Chemical symbol, symbol F and atomic number 9. It is the lightest halogen and exists at Standard temperature and pressure, standard conditions as pale yellow Diatomic molecule, diatomic gas. Fluorine is extre ...
(F),
chlorine
Chlorine is a chemical element; it has Symbol (chemistry), symbol Cl and atomic number 17. The second-lightest of the halogens, it appears between fluorine and bromine in the periodic table and its properties are mostly intermediate between ...
(Cl),
bromine
Bromine is a chemical element; it has chemical symbol, symbol Br and atomic number 35. It is a volatile red-brown liquid at room temperature that evaporates readily to form a similarly coloured vapour. Its properties are intermediate between th ...
(Br),
iodine (I) and
astatine
Astatine is a chemical element; it has Symbol (chemistry), symbol At and atomic number 85. It is the abundance of elements in Earth's crust, rarest naturally occurring element in the Earth's crust, occurring only as the Decay chain, decay product ...
(At), ending which was continued in the artificially created
tennessine (Ts).
The suffix ''
-in'' () is
etymologically related and
overlaps in usage with ''-ine''. Many
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metab ...
s and
lipid
Lipids are a broad group of organic compounds which include fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E and K), monoglycerides, diglycerides, phospholipids, and others. The functions of lipids include storing ...
s have names ending with ''-in'': for example, the enzymes
pepsin and
trypsin, the hormones
insulin
Insulin (, from Latin ''insula'', 'island') is a peptide hormone produced by beta cells of the pancreatic islets encoded in humans by the insulin (''INS)'' gene. It is the main Anabolism, anabolic hormone of the body. It regulates the metabol ...
and
gastrin
Gastrin is a peptide hormone that stimulates secretion of gastric acid (HCl) by the parietal cells of the stomach and aids in gastric motility. It is released by G cells in the pyloric antrum of the stomach, duodenum, and the pancreas.
...
, and the lipids
stearin
Stearin , or tristearin, or glyceryl tristearate is an odourless, white powder. It is a triglyceride derived from three units of stearic acid. Most triglycerides are derived from at least two and more commonly three different fatty acids. Like ...
(stearine) and
olein.
References
{{Orgchemsuffixes
ine
English suffixes