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Voacristine
Voacristine is a indole alkaloid occurring in '' Voacanga'' and '' Tabernaemontana'' genus. It is also an iboga type alkaloid. Chemistry Its structure is almost similar to voacangine, an alkaloid used in semi-synthesis of ibogaine. Compared to voacangine, it has an extra O-atom. When it is degraded, iboxygaine and ibogaine are formed. Sources Voacristine is found in multiple species of '' Tabernaemontana'' including '' Tabernaemontana divaricata'', '' Tabernaemontana heyneana'', '' Tabernaemontana ventricosa'', and '' Voacanga africana''. See also * Heyneanine * Voacamine * Vobasine References Tryptamine alkaloids {{Alkaloid-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vobasine
Vobasine is a naturally occurring monoterpene indole alkaloid found in several species in the genus ''Tabernaemontana'' including ''Tabernaemontana divaricata''. History Vobasine was first reported by Renner in 1959 after its isolation from ''Voacanga africana''. The two structurally related compounds, dregamine and tabernaemontanine, where its alkene (=CHCH3) sidechain was redox, reduced to ethyl groups in two molecular_configuration, configurations, had their relationship confirmed in the 1970s. Vobasine has been found in many plants of the dogbane (Apocynaceae) family including ''Tabernaemontana dichotoma''. Synthesis Biosynthesis As with other Indole alkaloids, the biosynthesis of vobasine starts from the amino acid tryptophan. This is converted into strictosidine before further elaboration. Chemical synthesis The synthesis of alkaloids with the same carbon skeleton as vobasine began in the 1960s and has continued, with some work providing enantioselective synthesis, enantio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tabernaemontana Heyneana
''Tabernaemontana alternifolia'' is a species of plant in the family Apocynaceae. It is endemic to India. Taxonomy The name ''Tabernaemontana heyneana'' Wall. has often been used for this species, and a proposal was made to conserve that name so that it would be used instead of ''T. alternifolia''. Arguments made for conservation were that the type of the species was not a specimen but an illustration, and that the plant has opposite leaves In botany, phyllotaxis () or phyllotaxy is the arrangement of leaf, leaves on a plant stem. Phyllotactic spirals form a distinctive class of patterns in nature. Leaf arrangement The basic leaf#Arrangement on the stem, arrangements of leaves ..., not alternate leaves as ''alternifolia'' implies. However, the proposal was rejected, and the correct name of this species is the original name, ''T. alternifolia''. Image:Tabernaemontana alternifolia 26.JPG, Unripe fruit Image:Tabernaemontana alternifolia 21.JPG, Ripe fruit References * ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Voacamine
Voacamine, also known under the older names voacanginine and vocamine, is a naturally occurring dimeric indole alkaloid of the secologanin type, found in a number of plants, including ''Voacanga africana'' and ''Tabernaemontana divaricata''. It is approved for use as an antimalarial drug in several African countries. Voacamine exhibits cannabinoid CB1 receptor antagonistic activity. Chemistry Structure There is considerable confusion about the absolute stereochemical configuration of voacamine and the originally published absolute structure had to be later revised. It has an ibogaine unit joined with vobasine unit. Adverse Effect Voacamine can cause hypertension in high dose. See also * Vincamine * Voacangine Voacangine (12-methoxyibogamine-18-carboxylic acid methyl ester) is an alkaloid found predominantly in the root bark of the ''Voacanga africana'' tree, as well as in other plants such as '' Tabernanthe iboga'', ''Tabernaemontana africana'', '' Tra ... * Vobtusine R ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heyneanine
Heyneanine is a ''Tabernaemontana'' alkaloid with ''in vitro'' antitumor activity. It also inhibits butrylcholinesterase. See also * Coronaridine * Voacangine Voacangine (12-methoxyibogamine-18-carboxylic acid methyl ester) is an alkaloid found predominantly in the root bark of the ''Voacanga africana'' tree, as well as in other plants such as '' Tabernanthe iboga'', ''Tabernaemontana africana'', '' Tra ... References Indole alkaloids Heterocyclic compounds with 5 rings Methyl esters {{alkaloid-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Voacanga Africana
''Voacanga'' is a genus of plants in the family Apocynaceae found in Africa, Southeast Asia, New Guinea, and Australia. the World Checklist of Selected Plant Families recognises 13 species:Search for "Voacanga", ;Species # ''Voacanga africana'' Otto Stapf (botanist), Stapf ex George Francis Scott-Elliot, Scott-Elliot - tropical W + C + E + S Africa # ''Voacanga bracteata'' Stapf - tropical W + C Africa # ''Voacanga caudiflora'' Stapf - tropical W Africa # ''Voacanga chalotiana'' Jean Baptiste Louis Pierre, Pierre ex Stapf - tropical C Africa # ''Voacanga foetida'' (Carl Ludwig Blume, Blume) Robert Allen Rolfe, Rolfe -Java, Borneo, Sumatra, Philippines # ''Voacanga globosa'' (Francisco Manuel Blanco, Blanco) Elmer Drew Merrill, Merr. - Philippines # ''Voacanga gracilipes'' (Friedrich Anton Wilhelm Miquel, Miq.) Friedrich Markgraf, Markgr. - Maluku # ''Voacanga grandifolia'' (Miq.) Rolfe - Indonesia, Philippines, New Guinea, Queensland # ''Voacanga havilandii'' Henry Nicholas Rid ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Natural Product Research
''Natural Product Research'' is a peer-reviewed scientific journal covering research on natural products chemistry. It was established in 1992 by Atta-ur-Rahman. Abstracting and indexing The journal is abstracted and indexed in *CAB Abstracts *Cambridge Crystallographic Data Centre *Chemical Abstracts Service *National Library of Medicine *PubMed *Science Citation Index Expanded *Scopus Scopus is a scientific abstract and citation database, launched by the academic publisher Elsevier as a competitor to older Web of Science in 2004. The ensuing competition between the two databases has been characterized as "intense" and is c .... Taylor & Francis academic journals English-language journals Chemistry journals {{chemistry-journal-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tabernaemontana Ventricosa
''Tabernaemontana'' is a genus of flowering plants in the family Apocynaceae. It has a pan-tropical distribution, found in Asia, Africa, Australia, North America, South America, and islands of the Indian and Pacific Oceans. These plants are evergreen shrubs and small trees growing to 1–15 m tall. The leaves are arranged in opposite pairs, 3–25 cm long, with milky sap; hence it is one of the diverse plant genera commonly called "milkwood". The flowers are fragrant, white, 1–5 cm in diameter. The cultivar '' T. divaricata'' cv. 'Plena', with doubled-petaled flowers, is a popular houseplant. Some members of the genus ''Tabernaemontana'' are used as additives to some versions of the psychedelic drink ayahuasca; the genus is known to contain ibogaine (e.g. in bëcchëte, ''T. undulata''), conolidine (present in minor concentration in ''T. divaricata'') and voacangine ('' T. alba'', '' T. arborea'', '' T. africana''). Because of presence of coronaridine and voacangine ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Planta Medica
''Planta Medica'' is a peer-reviewed journal published by Thieme Medical Publishers and covers medicinal plants and bioactive natural products of natural origin. ''Planta Medica'' is the official journal of the Society for Medicinal Plant and Natural Product Research (GA). According to the ''Journal Citation Reports'', the journal's 2016 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a type of journal ranking. Journals with higher impact factor values are considered more prestigious or important within their field. The Impact Factor of a journa ... is 2.342. Planta Medica is a Q1 journal in integrative and complementary medicine, and a Q2 journal in plant sciences. Oliver Kayser, from the TU Dortmund University, and Robert Fuerst, Wolfgang-von-Goethe University Frankfurt are the editors-in-chief. In the 18 issues published per year, Planta Medica covers the following areas of medicinal plants and natural product research: * ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Voacanga
''Voacanga'' is a genus of plants in the family Apocynaceae found in Africa, Southeast Asia, New Guinea, and Australia. the World Checklist of Selected Plant Families recognises 13 species:Search for "Voacanga", ;Species # ''Voacanga africana'' Stapf ex Scott-Elliot - tropical W + C + E + S Africa # '' Voacanga bracteata'' Stapf - tropical W + C Africa # '' Voacanga caudiflora'' Stapf - tropical W Africa # '' Voacanga chalotiana'' Pierre ex Stapf - tropical C Africa # '' Voacanga foetida'' ( Blume) Rolfe -Java, Borneo, Sumatra, Philippines # '' Voacanga globosa'' (Blanco Blanco (''white'' or ''blank'' in Spanish) or Los Blancos may refer to: People *Blanco (surname) Fictional characters *Blanco, a hobbit in J. R. R. Tolkien's Middle-earth *Blanco Webb, character in the BBC sitcom ''Porridge'' *Graboid#El Blanco, ...) Merr. - Philippines # '' Voacanga gracilipes'' ( Miq.) Markgr. - Maluku # '' Voacanga grandifolia'' (Miq.) Rolfe - Indonesia, Philippines, New Guinea, Que ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tabernaemontana
''Tabernaemontana'' is a genus of flowering plants in the family Apocynaceae. It has a pan-tropical distribution, found in Asia, Africa, Australia, North America, South America, and islands of the Indian and Pacific Oceans. These plants are evergreen shrubs and small trees growing to 1–15 m tall. The leaves are arranged in opposite pairs, 3–25 cm long, with milky sap; hence it is one of the diverse plant genera commonly called "milkwood". The flowers are fragrant, white, 1–5 cm in diameter. The cultivar ''Tabernaemontana divaricata, T. divaricata'' cv. 'Plena', with doubled-petaled flowers, is a popular houseplant. Some members of the genus ''Tabernaemontana'' are used as additives to some versions of the psychedelic drink ayahuasca; the genus is known to contain ibogaine (e.g. in bëcchëte, ''T. undulata''), conolidine (present in minor concentration in ''T. divaricata'') and voacangine (''Tabernaemontana alba, T. alba'', ''Tabernaemontana arborea, T. arborea'' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tabernaemontana Divaricata
''Tabernaemontana divaricata'', commonly called pinwheel flower, crape jasmine, East India rosebay, and Nero's crown, is an evergreen shrub or small tree native to South Asia, Southeast Asia and China. In zones where it is not hardy it is grown as a house/glasshouse plant for its attractive flowers and foliage. The stem exudes a milky latex when broken, whence comes the name milk flower Description The plant generally grows to a height of and is dichotomously branched. The large shiny leaves are deep green and about in length and in width. The waxy blossoms are found in small clusters on the stem tips. The (single) flowers have the characteristic 'pinwheel' shape also seen in other genera in the family Apocynaceae such as '' Vinca'' and '' Nerium''. Both single and double-flowered forms are cultivated, the flowers of both forms being white. The plant blooms in spring but flowers appear sporadically all year. The flowers have a pleasing fragrance. More than 66 alkaloids are ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ibogaine
Ibogaine is a psychoactive indole alkaloid derived from plants such as '' Tabernanthe iboga'', characterized by hallucinogenic and oneirogenic effects. Traditionally used by Central African foragers, it has undergone controversial research for the treatment of substance use disorders. Ibogaine exhibits complex pharmacology by interacting with multiple neurotransmitter systems, notably affecting opioid, serotonin, sigma, and NMDA receptors, while its metabolite noribogaine primarily acts as a serotonin reuptake inhibitor and κ-opioid receptor agonist. The psychoactivity of the root bark of the iboga tree, ''T. iboga'', one of the plants from which ibogaine is extracted, was first discovered by forager tribes in Central Africa, who passed the knowledge to the Bwiti tribe of Gabon. It was first documented in the 19th century for its spiritual use, later isolated and synthesized for its psychoactive properties, briefly marketed in Europe as a stimulant, and ultimately rese ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
