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Virus Core
A capsid is the protein shell of a virus, enclosing its genetic material. It consists of several oligomeric (repeating) structural subunits made of protein called protomers. The observable 3-dimensional morphological subunits, which may or may not correspond to individual proteins, are called capsomeres. The proteins making up the capsid are called capsid proteins or viral coat proteins (VCP). The virus genomic component inside the capsid, along with occasionally present virus core protein, is called the virus core. The capsid and core together are referred to as a nucleocapsid (cf. also virion). Capsids are broadly classified according to their structure. The majority of the viruses have capsids with either helical or icosahedral structure. Some viruses, such as bacteriophages, have developed more complicated structures due to constraints of elasticity and electrostatics. The icosahedral shape, which has 20 equilateral triangular faces, approximates a sphere, while the h ...
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Golgi Apparatus
The Golgi apparatus (), also known as the Golgi complex, Golgi body, or simply the Golgi, is an organelle found in most eukaryotic Cell (biology), cells. Part of the endomembrane system in the cytoplasm, it protein targeting, packages proteins into membrane-bound Vesicle (biology and chemistry), vesicles inside the cell before the vesicles are sent to their destination. It resides at the intersection of the secretory, lysosomal, and Endocytosis, endocytic pathways. It is of particular importance in processing proteins for secretion, containing a set of glycosylation enzymes that attach various sugar monomers to proteins as the proteins move through the apparatus. The Golgi apparatus was identified in 1898 by the Italian biologist and pathologist Camillo Golgi. The organelle was later named after him in the 1910s. Discovery Because of its large size and distinctive structure, the Golgi apparatus was one of the first organelles to be discovered and observed in detail. It was d ...
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List Of Geodesic Polyhedra And Goldberg Polyhedra
A list is a set of discrete items of information collected and set forth in some format for utility, entertainment, or other purposes. A list may be memorialized in any number of ways, including existing only in the mind of the list-maker, but lists are frequently written down on paper, or maintained electronically. Lists are "most frequently a tool", and "one does not ''read'' but only ''uses'' a list: one looks up the relevant information in it, but usually does not need to deal with it as a whole".Lucie Doležalová,The Potential and Limitations of Studying Lists, in Lucie Doležalová, ed., ''The Charm of a List: From the Sumerians to Computerised Data Processing'' (2009). Purpose It has been observed that, with a few exceptions, "the scholarship on lists remains fragmented". David Wallechinsky, a co-author of '' The Book of Lists'', described the attraction of lists as being "because we live in an era of overstimulation, especially in terms of information, and lists help us ...
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Goldberg Polyhedra
In mathematics, and more specifically in polyhedral combinatorics, a Goldberg polyhedron is a convex polyhedron made from hexagons and pentagons. They were first described in 1937 by Michael Goldberg (1902–1990). They are defined by three properties: each face is either a pentagon or hexagon, exactly three faces meet at each vertex, and they have rotational icosahedral symmetry. They are not necessarily mirror-symmetric; e.g. and are enantiomorphs of each other. A Goldberg polyhedron is a dual polyhedron of a geodesic polyhedron. A consequence of Euler's polyhedron formula is that a Goldberg polyhedron always has exactly 12 pentagonal faces. Icosahedral symmetry ensures that the pentagons are always regular and that there are always 12 of them. If the vertices are not constrained to a sphere, the polyhedron can be constructed with planar equilateral (but not in general equiangular) faces. Simple examples of Goldberg polyhedra include the dodecahedron and truncated icos ...
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Aaron Klug
Sir Aaron Klug (11 August 1926 – 20 November 2018) was a British biophysicist and chemist. He was a winner of the 1982 Nobel Prize in Chemistry for his development of crystallographic electron microscopy and his structural elucidation of biologically important nucleic acid-protein complexes. Early life and education Klug was born in Želva, in Lithuania, to Jewish parents Lazar, a cattleman, and Bella (née Silin) Klug, with whom he emigrated to South Africa at the age of two. He was educated at Durban High School. Paul de Kruif's 1926 book, '' Microbe Hunters'', aroused his interest in microbiology. Klug was part of the Hashomer Hatzair Jewish Zionist youth movement in South Africa. He started to study microbiology, but then moved into physics and maths, graduating with a Bachelor of Science degree at the University of the Witwatersrand, in Johannesburg. He studied physics under Reginald W. James and obtained his Master of Science degree at the University of Cape Town. ...
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Donald Caspar
Donald L. D. Caspar (January 8, 1927 – November 27, 2021) was an American structural biologist (the very term he coined) known for his works on the structures of biological molecules, particularly of the tobacco mosaic virus. He was an emeritus professor of biological science at the Institute of Molecular Biophysics, Florida State University, and an emeritus professor of biology at the Rosenstiel Basic Medical Sciences Research Center, Brandeis University. He has made significant scientific contributions in virus biology, X-ray, neutron and electron diffraction, and protein plasticity. Caspar completed his BA in physics from Cornell University in 1950. He joined Yale University from where he earned his PhD in biophysics in 1955. He was supervised by Ernest C. Pollard. His thesis was on the structure of tobacco mosaic virus (TMV) titled ''The Radial Structure of Tobacco Mosaic Virus''. While waiting for his degree he worked under Max Delbrück at the California Institute of Tec ...
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Icosahedron
In geometry, an icosahedron ( or ) is a polyhedron with 20 faces. The name comes . The plural can be either "icosahedra" () or "icosahedrons". There are infinitely many non- similar shapes of icosahedra, some of them being more symmetrical than others. The best known is the ( convex, non- stellated) regular icosahedron—one of the Platonic solids—whose faces are 20 equilateral triangles. Regular icosahedra There are two objects, one convex and one nonconvex, that can both be called regular icosahedra. Each has 30 edges and 20 equilateral triangle faces with five meeting at each of its twelve vertices. Both have icosahedral symmetry. The term "regular icosahedron" generally refers to the convex variety, while the nonconvex form is called a ''great icosahedron''. Convex regular icosahedron The convex regular icosahedron is usually referred to simply as the ''regular icosahedron'', one of the five regular Platonic solids, and is represented by its Schläfli symbol , contai ...
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Virus Capsid T Number
A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Viruses are found in almost every ecosystem on Earth and are the most numerous type of biological entity. Since Dmitri Ivanovsky's 1892 article describing a non-bacterial pathogen infecting tobacco plants and the discovery of the tobacco mosaic virus by Martinus Beijerinck in 1898, more than 16,000 of the millions of virus species have been described in detail. The study of viruses is known as virology, a subspeciality of microbiology. When infected, a host cell is often forced to rapidly produce thousands of copies of the original virus. When not inside an infected cell or in the process of infecting a cell, viruses exist in the form of independent viral particles, or ''virions'', consisting of (i) genetic material, i.e., long molecules of DNA or RNA that encode ...
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