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Tris(2,3-dibromopropyl)phosphate
Tris(2,3-dibromopropyl) phosphate ("tris") is a chemical once widely used as a flame retardant in plastics and textiles. Safety and regulation Tris is mutagenic and listed as an IARC Group 2A carcinogen. It is one of the chemicals covered by the Rotterdam Convention. In the United States, the Consumer Product Safety Commission banned the sale of children's garments containing tris in 1977. This regulatory change came about as a result of the research of Bruce Ames and Arlene Blum Arlene Blum (born March 1, 1945Breaking Trail: A Climbing Life, page 34Chapter 24 /ref>) is an American mountaineer, writer, and environmental health scientist. She is best known for leading the first successful American ascent of Annapurna (I .... See also * Tris(1,3-dichloro-2-propyl)phosphate * Tris(2-chloroethyl) phosphate References {{organic-compound-stub Organophosphates Organobromides Flame retardants IARC Group 2A carcinogens ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Flame Retardant
Flame retardants are a diverse group of chemicals that are added to manufactured materials, such as plastics and textiles, and surface finishes and coatings. Flame retardants are activated by the presence of an combustion, ignition source and prevent or slow the further development of flames by a variety of different physical and chemical mechanisms. They may be added as a copolymer during the polymerisation process, or later added to the polymer at a moulding or extrusion process or (particularly for textiles) applied as a topical finish. Mineral flame retardants are typically additive, while organohalogen and organophosphorus compounds can be either reactive or additive. Classes Both reactive and additive flame retardants types can be further separated into four distinct classes: * Minerals such as aluminium hydroxide (ATH), magnesium hydroxide (MDH), huntite and hydromagnesite, various hydrates, red phosphorus, and boron compounds, mostly borates. * Organohalogen compounds. Th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of IARC Group 2A Carcinogens
IARC group 2A agents are substances and exposure circumstances that have been classified as probable carcinogens by the International Agency for Research on Cancer (IARC). This designation is applied when there is limited evidence of carcinogenicity in humans, as well as ''sufficient evidence'' of carcinogenicity in experimental animals. In some cases, an agent may be classified in this group when there is ''inadequate evidence'' of carcinogenicity in humans along with ''sufficient evidence'' of carcinogenicity in experimental animals and ''strong evidence'' that the carcinogenesis is mediated by a mechanism that also operates in humans. Exceptionally, an agent may be classified in this group solely on the basis of ''limited evidence'' of carcinogenicity in humans. This list is focusing on the hazard linked to the agents. This means that the carcinogenic agents are capable of causing cancer, but this does not take their risk into account, which is the probability of causing a can ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rotterdam Convention
The Rotterdam Convention (formally, the Rotterdam Convention on the Prior Informed Consent Procedure for Certain Hazardous Chemicals and Pesticides in International Trade) is a multilateral treaty to promote shared responsibilities in relation to importation of hazardous chemicals. The convention promotes open exchange of information and calls on exporters of hazardous chemicals to use proper labeling, include directions on safe handling, and inform purchasers of any known restrictions or bans. Signatory nations can decide whether to allow or ban the importation of chemicals listed in the treaty, and exporting countries are obliged to make sure that producers within their jurisdiction comply. In 2012, the Secretariats of the Basel Convention, Basel and Stockholm Convention on Persistent Organic Pollutants, Stockholm conventions, as well as the United Nations Environment Programme, UNEP-part of the Rotterdam Convention Secretariat, merged to a single Secretariat with a matrix s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Consumer Product Safety Commission
The United States Consumer Product Safety Commission (USCPSC, CPSC, or commission) is an independent agency of the United States government. The CPSC seeks to promote the safety of consumer products by addressing "unreasonable risks" of injury (through coordinating recalls, evaluating products that are the subject of consumer complaints or industry reports, etc.); developing uniform safety standards (some mandatory, some through a voluntary standards process); and conducting research into product-related illness and injury. The agency was created by section 4 of the Consumer Product Safety Act in 1972. The agency reports to Congress and the President; it is not part of any other department or agency in the federal government. The CPSC has five commissioners, who are nominated by the president and confirmed by the Senate for staggered seven-year terms. Historically, the commission was often run by three commissioners or fewer. Since 2009, however, the agency has generally been ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bruce Ames
Bruce Nathan Ames (December 16, 1928 – October 5, 2024) was an American biochemist who was a professor of biochemistry and Molecular Biology Emeritus at the University of California, Berkeley, and was a senior scientist at Children's Hospital Oakland Research Institute (CHORI). Ames made contributions to understanding the mechanisms of mutagenesis and DNA repair. He invented the Ames test, a widely used assay for easily and cheaply evaluating the mutagenicity of compounds. The test revolutionized the field of toxicology and has played a crucial role in identifying numerous environmental and industrial carcinogens. Biography Ames, raised in New York City, was a graduate of the Bronx High School of Science. His undergraduate studies were at Cornell University in Ithaca, New York, and his graduate studies were completed at the California Institute of Technology. Ames was elected a Fellow of the American Academy of Arts and Sciences in 1970. He is a recipient of the Bolton S. Co ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Arlene Blum
Arlene Blum (born March 1, 1945Breaking Trail: A Climbing Life, page 34Chapter 24 /ref>) is an American mountaineer, writer, and environmental health scientist. She is best known for leading the first successful American ascent of Annapurna (I), a climb that was also an all-woman ascent. She led the first all-woman ascent of Denali ("Denali Damsels" expedition), and was the first American woman to attempt Mount Everest.Blum, Arlene. Personal Interview. December 5, 2009. She is executive director of the Green Science Policy Institute, an organization of scientists who develop and communicate peer-reviewed research to develop innovative solutions to reduce the use of toxic chemicals. Early life Blum was born in Davenport, Iowa, and raised from the age of five on in Chicago by her Orthodox Jewish grandparents and mother. In the early 1960s, she attended Reed College in Portland, Oregon. Her first climb was in Washington, where she failed to reach the summit of Mount Adams. Howe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tris(1,3-dichloro-2-propyl)phosphate
Tris(1,3-dichloroisopropyl)phosphate (TDCPP) is a chlorinated organophosphate. Organophosphate chemicals have a wide variety of applications and are used as flame retardants, pesticides, plasticizers, and nerve gases. TDCPP is structurally similar to several other organophosphate flame retardants, such as tris(2-chloroethyl) phosphate (TCEP) and tris(chloropropyl)phosphate (TCPP). TDCPP and these other chlorinated organophosphate flame retardants are all sometimes referred to as "chlorinated tris". Manufacture TDCPP is produced by the reaction of epichlorohydrin with phosphorus oxychloride. Uses Flame retardant Until the late 1970s, TDCPP was used as a flame retardant in children’s pajamas in compliance with the U.S. Flammable Fabrics Act of 1953. This use was discontinued after children wearing fabrics treated with a very similar compound, tris(2,3-dibromopropyl) phosphate, were found to have mutagenic byproducts in their urine. Following the 2005 phase-out of PentaB ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tris(2-chloroethyl) Phosphate
Tris(2-chloroethyl) phosphate (TCEP) is a chemical compound used as a flame retardant, plasticizer, and viscosity regulator in various types of polymers including polyurethanes, polyester resins, and polyacrylates. Safety Because of its suspected reproductive toxicity, it is listed as a substance of very high concern under the European Union The European Union (EU) is a supranational union, supranational political union, political and economic union of Member state of the European Union, member states that are Geography of the European Union, located primarily in Europe. The u ...'s REACH regulations. Its use has been largely replaced by tris(chloropropyl) phosphate, which is safer. See also * Tris(2,3-dibromopropyl) phosphate References {{Reflist Organophosphates Flame retardants Chloroethyl compounds ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Organophosphates
In organic chemistry, organophosphates (also known as phosphate esters, or OPEs) are a class of organophosphorus compounds with the general structure , a central phosphate molecule with alkyl or aromatic substituents. They can be considered as esters of phosphoric acid. Organophosphates are best known for their use as pesticides. Like most functional groups, organophosphates occur in a diverse range of forms, with important examples including key biomolecules such as DNA, RNA and ATP, as well as many insecticides, herbicides, nerve agents and flame retardants. OPEs have been widely used in various products as flame retardants, plasticizers, and performance additives to engine oil. The low cost of production and compatibility to diverse polymers made OPEs to be widely used in industry including textile, furniture, electronics as plasticizers and flame retardants. These compounds are added to the final product physically rather than by chemical bond. Due to this, OPEs leak int ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Organobromides
Organobromine chemistry is the study of the synthesis and properties of organobromine compounds, also called organobromides, which are organic compounds that contain carbon Chemical bond, bonded to bromine. The most pervasive is the naturally produced bromomethane. One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. General properties Most organobromine compounds, like most organohalogens, organohalide compounds, are relatively nonpolar. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon–bromine bond is electrophilic, i.e. alkyl bromides are alkylating ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Flame Retardants
Flame retardants are a diverse group of chemicals that are added to manufactured materials, such as plastics and textiles, and surface finishes and coatings. Flame retardants are activated by the presence of an combustion, ignition source and prevent or slow the further development of flames by a variety of different physical and chemical mechanisms. They may be added as a copolymer during the polymerisation process, or later added to the polymer at a moulding or extrusion process or (particularly for textiles) applied as a topical finish. Mineral flame retardants are typically additive, while organohalogen and organophosphorus compounds can be either reactive or additive. Classes Both reactive and additive flame retardants types can be further separated into four distinct classes: * Minerals such as aluminium hydroxide (ATH), magnesium hydroxide (MDH), huntite and hydromagnesite, various hydrates, red phosphorus, and boron compounds, mostly borates. * Organohalogen compounds. Th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
