Tetramethoxyphenethylamine
Tetramethoxyphenethylamines (TeMPEA) are a group of positional isomers of the psychedelic cactus alkaloid mescaline. Some of them are described in the book PiHKAL by Alexander Shulgin and Ann Shulgin. * 2,3,4,5-Tetramethoxyphenethylamine (TeMPEA-1) * TeMPEA-2 (2,3,4,6-tetramethoxyphenethylamine) * TeMPEA-3 (2,3,5,6-tetramethoxyphenethylamine) * BOM (drug) (3,4,5,β-tetramethoxyphenethylamine) See also * Substituted methoxyphenethylamine * Methoxyphenethylamine * Dimethoxyphenethylamine * Methoxyamphetamine * Dimethoxyamphetamine * Trimethoxyphenethylamine Trimethoxyphenethylamines (TMPEA) are a group of positional isomers of the psychedelic cactus alkaloid mescaline. Some of them are described in the book PiHKAL by Alexander Shulgin and Ann Shulgin. * 2,3,4-trimethoxyphenethylamine ( Isomescaline) * ... {{Phenethylamines Methoxyphenethylamines ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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TeMPEA-2
2,3,4,6-Tetramethoxyphenethylamine (2,3,4,6-TeMPEA), also known as TeMPEA-2, is a drug of the phenethylamine family related to the psychedelic drug mescaline (3,4,5-trimethoxyphenethylamine). It is one of the possible positional isomers of tetramethoxyphenethylamine (TeMPEA). The ''in-vitro'' metabolism and effects of TeMPEA-2 on behavior in animals have been studied. The drug showed little or no activity as a norepinephrine releasing agent ''in vitro''. It does not seem to have been tested in humans. TeMPEA-2 was first described in the scientific literature by 1955. See also * Substituted methoxyphenethylamine * Tetramethoxyphenethylamine (TeMPEA) * 2,3,4,5-Tetramethoxyphenethylamine (TeMPEA, TeMPEA-1) * 2,3,5,6-Tetramethoxyphenethylamine (TeMPEA-3) * 2,3,4,5-Tetramethoxyamphetamine (TeMA) * Pentamethoxyphenethylamine (PeMPEA) * Trimethoxyphenethylamine Trimethoxyphenethylamines (TMPEA) are a group of positional isomers of the psychedelic cactus alkaloid mescaline. Some of t ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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TeMPEA-3
2,3,5,6-Tetramethoxyphenethylamine (2,3,5,6-TeMPEA), also known as TeMPEA-3, is a drug of the phenethylamine family related to the psychedelic drug mescaline (3,4,5-trimethoxyphenethylamine). It is one of the possible positional isomers of tetramethoxyphenethylamine (TeMPEA). The ''in-vitro'' metabolism and effects of TeMPEA-3 on behavior in animals have been studied. Unlike mescaline, TeMPEA-3 was inactive in the conditioned avoidance response test in rats. The effects of TeMPEA-3 in humans have not been reported and are unknown. The drug was first described in the scientific literature by 1955. TeMPEA-3 was included as an entry in Alexander Shulgin's 2011 book '' The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds''. See also * Substituted methoxyphenethylamine * Tetramethoxyphenethylamine (TeMPEA) * 2,3,4,5-Tetramethoxyphenethylamine (TeMPEA, TeMPEA-1) * 2,3,4,6-Tetramethoxyphenethylamine (TeMPEA-2) * 2,3,4,5-Tetramethoxyamphetamine (TeMA) * Pent ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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2,3,4,5-Tetramethoxyphenethylamine
2,3,4,5-Tetramethoxyphenethylamine (TeMPEA) is a drug of the phenethylamine family related to mescaline (3,4,5-trimethoxyphenethylamine) and the 2C drugs (4-substituted 2,5-dimethoxyphenethylamines). It was reported to be twice as potent as mescaline in producing behavioral changes in animals. However, it does not seem to have been tested in humans. The drug was not described in Alexander Shulgin's PiHKAL, though it was included in '' The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds''. A derivative is 2,3,4,5-tetramethoxyamphetamine (TeMA), which ''was'' included in PiHKAL, and was reported to be inactive in humans at the tested doses. See also * Substituted methoxyphenethylamine Methoxyphenethylamines (MPEAs), as well as methoxyamphetamines (MAs) in the case of the amphetamine (α-methylphenethylamine) homologues, are substituted phenethylamines with one or more methoxy groups. In some cases, one or more of the methoxy ... References Ext ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Substituted Methoxyphenethylamine
Methoxyphenethylamines (MPEAs), as well as methoxyamphetamines (MAs) in the case of the amphetamine (α-methylphenethylamine) homologues, are substituted phenethylamines with one or more methoxy groups. In some cases, one or more of the methoxy groups may also be extended to form other alkoxy and related groups such as ethoxy or propoxy. Methoxyphenethylamines may have additional substitutions as well. Many methoxyphenethylamines that have multiple methoxy groups in the 2- through 5-positions of the phenyl ring, for instance mescaline, 2C-B, TMA, DOM, and 25I-NBOMe, are serotonin 5-HT2A receptor agonists and serotonergic psychedelics. Other methoxyphenethylamines, particularly monomethoxyamphetamines like ''para''-methoxyamphetamine (PMA), are monoamine releasing agents of serotonin, norepinephrine, and/or dopamine, with stimulant and/or entactogen-related effects. Compounds closely related to methoxyphenethylamines include methylenedioxyphenethylamines (MDxx) like M ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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BOM (drug)
BOM (3,4,5,beta-tetramethoxyphenethylamine) is a lesser-known drug of the BOx group. It is the β-methoxy derivative of mescaline. BOM was first synthesized by Alexander Shulgin. In his book ''PiHKAL'', the minimum dosage is listed as 200 mg, and the duration unknown. BOM produces few to no effects. Very little data exists about its pharmacological properties, metabolism, and toxicity. Legality United Kingdom This substance is a Class A drug in the Drugs controlled by the UK Misuse of Drugs Act The Misuse of Drugs Act 1971 (c. 38) is an act of the Parliament of the United Kingdom. It represents action in line with treaty commitments under the Single Convention on Narcotic Drugs, the Convention on Psychotropic Substances, and the Un .... References BOx (psychedelics) Phenylethanolamine ethers Scalines {{Psychoactive-stub ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Dimethoxyamphetamine
Dimethoxyamphetamine (DMA) is a series of six lesser-known psychedelic drugs similar in structure to the three isomers of methoxyamphetamine and six isomers of trimethoxyamphetamine. The isomers are 2,3-DMA, 2,4-DMA, 2,5-DMA, 2,6-DMA, 3,4-DMA, and 3,5-DMA. Three of the isomers were characterized by Alexander Shulgin in his book ''PiHKAL''. Little is known about their dangers or toxicity. Pharmacology 3,4-DMA, 2,4-DMA, 2,5-DMA, and their ''N''-methyl analogues all fail to produce stimulus generalization to dextroamphetamine in rodent drug discrimination tests, suggesting that they lack psychostimulant- or amphetamine-like effects, at least in rodents. This is in contrast to 2-methoxyamphetamine (OMA), 3-methoxyamphetamine (MMA), and 4-methoxyamphetamine (PMA), which all produce substitution for dextroampehtamine, albeit with far lower potency than amphetamine, methamphetamine, and other stimulants. Positional isomers 2,4-DMA * ''Dosage'': 60 mg or greater * ''Du ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Methoxyamphetamine
Methoxyamphetamine may refer to: * 2-Methoxyamphetamine (2-MA) or ''ortho''-methoxyamphetamine (OMA) * 3-Methoxyamphetamine (3-MA) or ''meta''-methoxyamphetamine (MMA) * 4-Methoxyamphetamine (4-MA) or ''para''-methoxyamphetamine (PMA) See also * Substituted methoxyphenethylamine * Dimethoxyamphetamine * Trimethoxyamphetamine * Methoxyphenethylamine * Dimethoxyphenethylamine * Trimethoxyphenethylamine Trimethoxyphenethylamines (TMPEA) are a group of positional isomers of the psychedelic cactus alkaloid mescaline. Some of them are described in the book PiHKAL by Alexander Shulgin and Ann Shulgin. * 2,3,4-trimethoxyphenethylamine ( Isomescaline) * ... {{Chemistry index Methoxyphenethylamines Substituted amphetamines ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Dimethoxyphenethylamine
Dimethoxyphenethylamine may refer to: * 2,3-Dimethoxyphenethylamine (2,3-DMPEA; DMPEA-2) * 2,4-Dimethoxyphenethylamine (2,4-DMPEA; DMPEA-3) * 2,5-Dimethoxyphenethylamine (2C-H; 2,5-DMPEA; DMPEA-4) * 2,6-Dimethoxyphenethylamine (2,6-DMPEA; DMPEA-5) * 3,4-Dimethoxyphenethylamine (3,4-DMPEA; DMPEA; DMPEA-1) * 3,5-Dimethoxyphenethylamine (3,5-DMPEA; DMPEA-6) See also * Substituted methoxyphenethylamine * Methoxyphenethylamine * Trimethoxyphenethylamine * Methoxyamphetamine * Dimethoxyamphetamine * Trimethoxyamphetamine 3,4,5-Trimethoxyamphetamine (TMA, TMA-1, or 3,4,5-TMA), also known as α-methylmescaline or mescalamphetamine, is a psychedelic drug of the phenethylamine and amphetamine families. It is one of the trimethoxyamphetamine (TMA) series of positiona ... {{Phenethylamines Methoxyphenethylamines ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Methoxyphenethylamine
Methoxyphenethylamine, or monomethoxyphenethylamine, may refer to: * 2-Methoxyphenethylamine (2-MPEA) * 3-Methoxyphenethylamine (3-MPEA) * 4-Methoxyphenethylamine (4-MPEA) See also * Substituted methoxyphenethylamine * Dimethoxyphenethylamine * Trimethoxyphenethylamine * Methoxyamphetamine * Dimethoxyamphetamine * Trimethoxyamphetamine 3,4,5-Trimethoxyamphetamine (TMA, TMA-1, or 3,4,5-TMA), also known as α-methylmescaline or mescalamphetamine, is a psychedelic drug of the phenethylamine and amphetamine families. It is one of the trimethoxyamphetamine (TMA) series of positiona ... {{Chemistry index Methoxyphenethylamines ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Positional Isomer
In chemistry, a structural isomer (or constitutional isomer in the IUPAC nomenclature) of a compound is a compound that contains the same number and type of atoms, but with a different connectivity (i.e. arrangement of bonds) between them. The term metamer was formerly used for the same concept. For example, butanol , methyl propyl ether , and diethyl ether have the same molecular formula but are three distinct structural isomers. The concept applies also to polyatomic ions with the same total charge. A classical example is the cyanate ion and the fulminate ion . It is also extended to ionic compounds, so that (for example) ammonium cyanate and urea are considered structural isomers,William F. Bynum, E. Janet Browne, Roy Porter (2014)''Dictionary of the History of Science'' page 218. and so are methylammonium formate and ammonium acetate . Structural isomerism is the most radical type of isomerism. It is opposed to stereoisomerism, in which the atoms and bonding s ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Psychedelic Drug
Psychedelics are a subclass of hallucinogenic drugs whose primary effect is to trigger non-ordinary mental states (known as psychedelic experiences or "trips") and a perceived "expansion of consciousness". Also referred to as classic hallucinogens or serotonergic hallucinogens, the term ''psychedelic'' is sometimes used more broadly to include various other types of hallucinogens as well, such as those which are atypical or adjacent to psychedelia like salvia and MDMA, respectively. Classic psychedelics generally cause specific psychological, visual, and auditory changes, and oftentimes a substantially altered state of consciousness. They have had the largest influence on science and culture, and include mescaline, LSD, psilocybin, and DMT. There are a large number of both naturally occurring and synthetic serotonergic psychedelics. Most psychedelic drugs fall into one of the three families of chemical compounds: tryptamines, phenethylamines, or lysergamides. T ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Ann Shulgin
Laura Ann Shulgin ( Gotlieb; March 22, 1931 – July 9, 2022) was an American author and the wife of chemist Alexander Shulgin, with whom she wrote ''PiHKAL'' and '' TiHKAL''. Life and career Laura Ann Gotlieb Detailed biography of Ann Shulgin was born in Wellington, New Zealand, to parents Bernard Gotlieb and Gwen Ormiston, but grew up in the village Opicina outside the Italian city Trieste. Her father was U.S. Consul in Trieste for six years before World War II. Later in her childhood she lived in the U.S., Cuba, and Canada. She studied art and became an artist, married an artist and had a child, and they later divorced. She had two more marriages ending in divorce and had three more children. Ann went back to work as a medical transcriber, and met Alexander ("Sasha") Shulgin in 1978; they were married on 4 July 1981 in their back yard. She worked as a lay therapist with psychedelic substances such as MDMA and 2C-B in therapeutic settings while these drugs were still legal ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |